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R1487 Hydrochloride
R1487 Hydrochloride from MedChemExpress
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Citations:
(1)
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R1487 Hydrochloride
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Description
R1487 Hydrochloride is a highly potent and selective
p38α
inhibitor, with
K
d
values of 0.2 nM and 29 nM for p38α and p38β, respectively
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
R1487 Hydrochloride
Company
MedChemExpress
Price
$138.00
Supplier Page
View Company Product Page
Catalog Number
HY-14975
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
98.96%
Type
Chemical
Molecular Weight
424.83
Formula
C₁₉H₁₉ClF₂N₄O₃
Research Area
Cancer
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (1)
(1)
Discovery of 6-(2,4-difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (pamapimod) and 6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (R1487) as orally bioavailable and highly selective inhibitors of p38α mitogen-activated protein kinase
Journal of medicinal chemistry
April 14, 2011
Goldstein DM, Soth M, Gabriel T, Dewdney N, Kuglstatter A, Arzeno H, Chen J, Bingenheimer W, Dalrymple SA, Dunn J,
et al
.
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R1487 Hydrochloride from MedChemExpress
Supplier Page
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$138.00
Product Specs
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