NK-252 from MedChemExpress

Product Specs
ItemNK-252
CompanyMedChemExpress
Price $73.00Supplier Page View Company Product Page
Catalog NumberHY-19734
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.60%
TypeChemical
Molecular Weight285.26
FormulaC₁₃H₁₁N₅O₃
Research AreaCancer

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(1) Plumbagin Induces Ferroptosis in Nonfunctioning Pituitary Adenomas via Nrf2/FTH1-Dependent FerritinophagyDrug Des Devel TherJune 26, 2026Dong Fan, Zongming Wang, Shixue Luo, Xuanhao Huang, Xingyi Yuan, Yanan Wang, Zhongyu Wang, Huitong Chen, Weiwen Wang, Yuxin Ma, et al.GLPBIO (2650557-72-3, USA), Temozolomide (TMZ) and NK-252 were purchased from MedChemExpress (HY-17364, HY-19734, New Jersey, USA). Primary Antibodies for Western Blot: anti-β-actin (1:8000, 66009-1, Proteintech,

(2) Dietary Polyunsaturated Fatty Acids Regulate Dendritic Cell Function via Nrf2-dependent Control of FerroptosisResearch SquareNovember 19, 2025Deepika Cubillos-Ruiz, Deepika Awasthi, Camilla Salvagno, Sung-Min Salvagno, Sung-Min Sandoval, Chang-Suk Sandoval, Wiam A. M. Madani, Jacqueline Madani, Jacqueline Crater, Kaushik Sen, et al.derivative that sequesters reactive lipid peroxidation byproducts; NK-252 (10 μM; MedChemExpress, Cat# HY-19734), a specific activator of the transcription factor Nrf2. CD8+ and CD4+ T cells were isolated from lymphoid tissues

(3) FBP1 controls liver cancer evolution from senescent MASH hepatocytesNatureJanuary 9, 2025Li Gu, Yahui Zhu, Shuvro P. Nandi, Maiya Lee, Kosuke Watari, Breanna Bareng, Masafumi Ohira, Yuxiao Liu, Sadatsugu Sakane, Rodrigo Carlessi, et al.chamber with 5% CO2. Etoposide (HY-13629), 5-azacytidine (HY-10586), BpV(HOpic) (HY-128693) and NK252 (HY-19734) were purchased from MCE. Human HCC specimens and scoring Human HCC specimens (n = 83) were acquired

(4) Downregulation of IL-8 and IL-10 by LRRC8A Inhibition through the NOX2–Nrf2–CEBPB Transcriptional Axis in THP-1-Derived M2 MacrophagesInternational Journal of Molecular SciencesSeptember 5, 2024Miki Matsui, Junko Kajikuri, Hiroaki Kito, Elghareeb E. Elboray, Takayoshi Suzuki, Susumu OhyaKit (02230-30) was from Nacalai Tesque (Kyoto, Japan). EDV (HY-105917), ANO1-IN-1 (HY-16320), NK252 (HY-19734), SU056 (HY-50231), and SKA121 (HY-107414) were from MedChemExpress (Monmouth Junction, NJ, USA). IL-10/IL-8

(5) ω-6 Polyunsaturated fatty acids (linoleic acid) activate both autophagy and antioxidation in a synergistic feedback loop via TOR-dependent and TOR-independent signaling pathwaysCell death & diseaseJuly 30, 2020Yang B, Zhou Y, Wu M, Li X, Mai K, Ai Q.3-MA (HY-19312; Monmouth Junction, NJ, MCE) or CQ (HY-17589; MCE), the Nrf2 pathway activator NK-252 (HY-19734; MCE), or the Nrf2 pathway inhibitor ML385 (HY-100523; MCE). Cell viability A CCK8 assay was performed

(6) Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat modelMolecular pharmacologyJuly 1, 2013Shimozono R, Asaoka Y, Yoshizawa Y, Aoki T, Noda H, Yamada M, Kaino M, Mochizuki H.

(7) Enhancement of antitumour activity of etoposide by dihydropyridines on drug-sensitive and drug-resistant leukaemia in miceBritish journal of cancerAugust 1, 1991Kiue A, Sano T, Naito A, Okumura M, Kohno K, Kuwano M.

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NK-252 from MedChemExpress

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NK-252 from MedChemExpress

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