SLF TFA from MedChemExpress | Biocompare.com

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SLF TFA

Description

SLF TFA is a synthetic ligand for FK506-binding protein (FKBP) with an affinity of 3.1 µM for FKBP51 and an IC₅₀ of 2.6 µM for FKBP12. SLF TFA can be used in the synthesis of PROTAC

Product Specs
ItemSLF TFA
CompanyMedChemExpress
Price $105.00Supplier Page View Company Product Page
Catalog NumberHY-114872A
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
FormulaC32H41F3N2O8
Research AreaCancer
TypeChemical
Molecular Weight638.67
Quantity10 mM * 1 mL
Molecule NameSLF (TFA)
Purity99.58%

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(1) Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16Nature chemical biologyJuly 1, 2019Zhang X, Crowley VM, Wucherpfennig TG, Dix MM, Cravatt BF.

(2) FKBP Ligands-Where We Are and Where to Go?Frontiers in pharmacologyJanuary 1, 2018Kolos JM, Voll AM, Bauder M, Hausch F.

(3) Creating diverse target-binding surfaces on FKBP12: synthesis and evaluation of a rapamycin analogue libraryACS combinatorial scienceSeptember 12, 2011Wu X, Wang L, Han Y, Regan N, Li PK, Villalona MA, Hu X, Briesewitz R, Pei D.

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