FITM from MedChemExpress | Biocompare.com

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FITM

Description

FITM is a negative allosteric modulator of mGlu1 receptor with a K_i of 2.5 nM

Product Specs
ItemFITM
CompanyMedChemExpress
Price $88.00Supplier Page View Company Product Page
Catalog NumberHY-101845
Research AreaCancer
FormulaC₁₈H₁₈FN₅OS
Molecular Weight371.43
TypeChemical
Purity99.85%
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Quantity10 mM * 1 mL

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(1) Investigation of allosteric modulation mechanism of metabotropic glutamate receptor 1 by molecular dynamics simulations, free energy and weak interaction analysisScientific reportsFebruary 18, 2016Bai Q, Yao X.

(2) Molecular imaging of ectopic metabotropic glutamate 1 receptor in melanoma with a positron emission tomography radioprobe (18) F-FITMInternational journal of cancerOctober 15, 2014Xie L, Yui J, Fujinaga M, Hatori A, Yamasaki T, Kumata K, Wakizaka H, Furutsuka K, Takei M, Jin ZH, et al.

(3) Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulatorScience (New York, N.Y.)April 4, 2014Wu H, Wang C, Gregory KJ, Han GW, Cho HP, Xia Y, Niswender CM, Katritch V, Meiler J, Cherezov V, et al.

(4) In vivo measurement of the affinity and density of metabotropic glutamate receptor subtype 1 in rat brain using 18F-FITM in small-animal PETJournal of nuclear medicine : official publication, Society of Nuclear MedicineOctober 1, 2012Yamasaki T, Fujinaga M, Kawamura K, Yui J, Hatori A, Ohya T, Xie L, Wakizaka H, Yoshida Y, Fukumura T, et al.

(5) Occurrence and properties of polygalacturonase in Avena and other plantsPlant physiologyOctober 1, 1977Pressey R, Avants JK.

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