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Protein Biochemistry
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KC7F2
KC7F2 from MedChemExpress
Be the first to write a review!
Citations:
(6)
Supplier Page
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MedChemExpress for
KC7F2
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Description
KC7F2 is a potent
hypoxia inducible factor-1 (HIF-1)
pathway inhibitor with an
IC
50
of 20 µM in LN229-HRE-AP cells, and with potential as a cancer therapy agent
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
KC7F2
Company
MedChemExpress
Price
$69.00
Supplier Page
View Company Product Page
Catalog Number
HY-18777
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.36%
Type
Chemical
Molecular Weight
570.38
Formula
C₁₆H₁₆Cl₄N₂O₄S₄
Research Area
Cancer
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (6)
(1)
Active LXR signaling, coupled with elevated mitochondrial and glycolytic metabolism contributes to GM-CSF–induced trained immunity
Frontiers in Immunology
January 7, 2026
Yuanyuan Liu, Arslan Hamid, Hannah Hardege, Qian Zhang, Helena Körner, Merle Leffers, Noelia A. Gonzalez, Gerhard Liebisch, Marcus Hoering, Hannes Findeisen,
et al.
2-DG (#
HY-13966
, CME), 10 μM (OSI-27) (
HY-10423
,
MCE
), 10 μM
KC7F2
(HIF1α
inhibitor
,
Medchemexpress
, #
HY-18777
), 50 μM UK5099 (mitochondrial pyruvate carrier (MPC)
inhibitor
,
Medchemexpress
, #
HY-15475
), 40 μM etomoxir
(2)
Berberine inhibits carcinogenesis through antagonizing the ATX-LPA-LPAR2-p38-leptin axis in a mouse hepatoma model
Molecular therapy oncolytics
September 15, 2022
Ren G, Guo JH, Feng CL, Ding YW, Dong B, Han YX, Li YH, Wang LL, Jiang JD.
HY-10295
), the HIF-1α
inhibitors
BAY 87-2243
(purity over 99%,
HY-15836
), and
KC7F2
(purity over 99%,
HY-18777
) were purchased from
MedChemExpress
(Shanghai, China). The antibody against autotaxin (
ATX
,
14243-1-AP
)
(3)
Hypoxia induces an endometrial cancer stem-like cell phenotype via HIF-dependent demethylation of SOX2 mRNA
Oncogenesis
September 11, 2020
Chen G, Liu B, Yin S, Li S, Guo Y, Wang M, Wang K, Wan X.
During culture, ECSCs were treated with CoCl2 (7646–79–9, Sigma-Aldrich, St. Louis, MO, USA) or
KC7F2
(
HY-18777
,
MedChemExpress
, Monmouth Junction, NJ, USA) as noted in the experiments. All siRNA products targeting
(4)
Monocarboxylate transporter 1 promotes classical microglial activation and pro-inflammatory effect via 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3
Journal of neuroinflammation
November 28, 2019
Kong L, Wang Z, Liang X, Wang Y, Gao L, Ma C.
37 °C under 5% CO2 atmosphere. Hif-1α
inhibitor
KC7F2
(40 μM, dissolved in dimethyl sulfoxide,
MCE
,
HY-18777
) and
MCT1
substrate L-lactate (5 mM, dissolved in PBS,
Sigma
, L7022) or pyruvate (5 mM, dissolved in
(5)
Identification of a novel small molecule HIF-1alpha translation inhibitor
Clinical cancer research : an official journal of the American Association for Cancer Research
October 1, 2009
Narita T, Yin S, Gelin CF, Moreno CS, Yepes M, Nicolaou KC, Van Meir EG.
(6)
"Donohue lecture series: ""Roe v. Wade: past and future"""
Suffolk University law review
September 1, 1990
Weddington S.
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KC7F2 from MedChemExpress
Supplier Page
View Company Product Page
$69.00
Product Specs
Company Info
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