Paclitaxel from MedChemExpress

Product Specs
ItemPaclitaxel
CompanyMedChemExpress
Price $66.00Supplier Page View Company Product Page
Catalog NumberHY-B0015
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.97%
TypeChemical
Molecular Weight853.91
FormulaC₄₇H₅₁NO₁₄
Research AreaCardiovascular Disease; Cancer

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(1) Anti-SIA-cIgG enhances chemotherapy effectiveness through PTPN13-regulated tumor stemness in head and neck squamous cell carcinomaJournal of Translational Internal MedicineApril 28, 2026Luming Wang, Yangyang Xia, Chenshu Liu, Xiaofeng Shan, Yi Sui, Shang Xie, Zhigang CaiMedChemExpress) dissolved in DMSO, docetaxel (#HY-B0011, MedChemExpress) dissolved in DMSO, paclitaxel (#HY-B0015, MedChemExpress) dissolved in DMSO, cetuximab (#HY-P9905, MedChemExpress), and RP215 (#sc-69849, Santa Cruz

(2) HE4 drives PD-L1 expression in myeloid cells via IFN-γR-JAK-STAT3 signaling to promote tumor immune evasionCell Reports MedicineApril 21, 2026Bo Zeng, Yingying Zhou, Heping Wang, Panyin Shu, Ting Pan, Fangfang Liu, Yangyang Li, Ming Yi, Ruirui He, Lingyun Feng, et al.HY-0172 JNK-IN-8,MedChemExpress,Cat# HY-13319 PD169316,MedChemExpress,Cat# HY-10578 paclitaxel,MedChemExpress,Cat# HY-B0015 ruxolitinib,MedChemExpress,Cat# HY-50856 erlotinib,MedChemExpress,Cat# HY-50896 HIF-1α-IN,MedChemExpress,Cat#

(3) DHX9 inhibition enhances paclitaxel sensitivity by inducing mitotic failure in ovarian and endometrial cancersMolecular Cancer TherapeuticsMarch 24, 2026Tzu-Ting Huang, Jayakumar R. Nair, Courtney Bowen, Jennifer Castro, Darryl Nousome, Sunaina Nayak, Serena J. Silver, Jung-Min Leeagreement (CRADA C-002-2024) and its chemical structure was previously reported (17). Paclitaxel (Cat# HY-B0015) was purchased from MedChemExpress. Z-VAD-FMK (Cat# S7023) were purchased from Selleck Chemicals. For

(4) Matrix structure and microenvironment dynamics correlate with chemotherapy response in ovarian canceriScienceMarch 20, 2026Florian Laforêts, Panoraia Kotantaki, Samar Elorbany, Joseph Hartlebury, Joash D. Joy, Beatrice Malacrida, Rachel C. Bryan-Ravenscroft, Chiara Berlato, Erica Di Federico, John F. Marshall, et al.Hospira), both from the pharmacy at St. Bartholomew’s Hospital, London or from Medchemexpress (HY-17393 and HY-B0015, respectively). Carboplatin and paclitaxel were administered to mice via i.p. in 200 μL volume starting

(5) A Comprehensive Adenoid Cystic Carcinoma-Derived Organoid Platform for Disease Modeling and Drug Screening Captures Interpatient HeterogeneityCellsFebruary 23, 2026Yingyue Chai, Yi Sui, Xinyuan Zhang, Shang Xie, Yifan Kang, Yanrui Feng, Xiaofeng Shan, Zhigang Cai(HY-90006, MedChemExpress, NJ, USA), Vincristine (HY-N0488A, MedChemExpress, NJ, USA), Paclitaxel (HY-B0015, MedChemExpress, NJ, USA), Docetaxel (S1148, Selleckchem, Houston, TX, USA), Regorafenib (HY-10331,

(6) Paclitaxel drives TREM2+ macrophage expansion underlying its inferior therapeutic efficacy compared to Nab-paclitaxelNature CommunicationsFebruary 3, 2026Yuqi Xing, Ruiqi Zhong, Qianchen Li, Xinwei Duan, Moyang Xu, Miao Yu, Chenying Liu, Junming He, Yi Sun, Yunling Wang, et al.showed paralysis, convulsions, or such phenomena, with the time of death recorded accordingly. The PTX (HY-B0015) was purchased from MedChemExpress and used at a concentration of 9 mg/kg. The Nab-PTX (HY-P99974) was

(7) Triptonide-mediated PTGS2 Inhibition Induces Autophagic Cell Death to Suppress the Progression of Triple-negative Breast Cancer and Epithelial Ovarian CancerInternational Journal of Biological SciencesJanuary 30, 2026Kunxiang Gong, Kai Song, Haotian Wang, Linye Li, Xiaomin Sun, Lingling Sun, Wenbo Hao, Zhe-Sheng Chen, Yinger HuangHY-111152), cisplatin (DDP, Cat# HY-17394), STAT3-IN-3 (Cat# HY-128588), and paclitaxel (PTX, Cat# HY-B0015) were purchased from MedChemExpress (Shanghai, China). Short hairpin RNA (shRNA) against PTGS2, small

(8) The prognostic significance of JAML and its role in remodeling the immune microenvironment via the cGAS-STING pathway in endometrial cancerFrontiers in ImmunologyJanuary 29, 2026Chenfan Tian, Yuanyang Yao, Yuan Tu, Jiaxin Yu, Chunxia Gong, Xiuling Shi, Hangkun Yu, Peng Jiangand untreated controls, were then exposed to specified concentrations of paclitaxel (MedChemExpress, HY-B0015) or cisplatin (MedChemExpress, HY-17394) for 14 days (38, 39). Colonies were fixed with 4% paraformaldehyde

(9) Utilization of a UPLC-MS/MS Approach to Elucidate the Role of ABCB1-Mediated Paclitaxel Resistance in Non-Small Cell Lung Cancer CellsOncology ResearchJanuary 19, 2026Sha Hu, Wenjing Wang, Qianfang Hu, Rujuan Zheng, Qinghe Huang, Hui Shi, Xinyuan Ding, Wenjuan Wang, Zengyan ZhuTechnologies, Waltham, MA, USA) and 200 ng/mL paclitaxel (MedChemExpress, Shanghai, China; Cat. No. HY-B0015). Both A549 and A549/TAX cells were incubated at 37°C with 5% CO2. All cell lines were authenticated

(10) High-content phenotyping reveals Golgi dynamics and their role in cell cycle regulationJournal of Cell BiologyJanuary 5, 2026Xun Cao, Yiming Peng, Mengyuan Yang, Mengling Gan, Di Zhang, Shiyue Zhou, Daisuke TakaoµM; 1362911; R&D Systems) for cell cycle synchronization; taxol (50 nM for mitosis or 1 µM for G2; HY-B0015; MedChemExpress), monastrol (100 nM; HY-101071A; MedChemExpress), SP600125 (50 µM; S5567; Sigma-Aldrich),

(11) The Crosstalk Between CRL5 and APC/C E3 Ligases Regulates Metastasis and Chemosensitivity of Cancer CellsAdvanced ScienceJanuary 1, 2026Danrui Cui, Ruirui Qu, Tianqi Li, Linchen Wang, Xiaoyu Chen, Shengpeng Shao, Xue Liang, Jun Xu, Yi Sun, Xiufang Xiong, et al.(MCE, HY‐10227), CQ (Sigma–Aldrich, C6628), Nocodazole (Sigma–Aldrich, M1404), and Paclitaxel (MCE, HY‐B0015). Tandem Affinity Purification and LC‐MS/MS Analysis MIA PaCa‐2 cells stably expressing SBP‐S‐CUL5

(12) Integrative analysis identifies PIGK as an oncogenic glycosylphosphatidylinositol transamidase subunit with prognostic, immunological, and therapeutic relevance in head and neck cancerInternational Journal of Medical SciencesJanuary 1, 2026Yi-Fang Yang, Jia-Bin Liao, Pei-Lun Yu, Chih-Yu Chou, Yu-Hsuan Linmeasured using an ELISA reader (Thermo Fisher Scientific; Multiskan FC). Cisplatin (HY-17394), paclitaxel (HY-B0015), and docetaxel (HY-B0011) were purchased from MCE. Lentivirus infection Lentiviral supernatants containing

(13) SNX1 inhibits human ovarian cancer progression via regulation of the cell cycle, apoptosis and migrationMol Cell OncolDecember 31, 2025Pin Li, Xiaoyan Yu, Kailing Wen, Lei Wang, Jingran Yu, Ping Chendrug treatment assays, cells were treated with either carboplatin (MCE, HY-17393) or paclitaxel (MCE, HY-B0015) for 24 hours. Each experimental condition included five technical replicates per group and was independently

(14) MASTL Promotes Hepatocellular Carcinoma Progression and Paclitaxel Resistance Through Mitotic CatastropheCancer ScienceDecember 5, 2025Ke Wang, Ziwei Fu, Chuan Xiong, Jing Zhang, Qiang Luo104 cells/well) and permitted to adhere for 24 h. Subsequently, they were exposed to paclitaxel (Cat# HY‐B0015, MedChemExpress) at concentrations ranging from 0 to 40 nM for an additional 48 h. CCK8 was used to

(15) TRIM25 degrades BRD7 protein stability through the ubiquitin proteasome pathway to promote breast cancer progression and paclitaxel resistance by activating YB1/Bcl-2 transcription axisCell Death & DiseaseNovember 28, 2025Changning Xue, Qingqing Wei, Mengna Li, Jianxia Wei, Lemei Zheng, Zubing Wu, Huizhen Xin, Yumei Duan, Songqing Fan, Wei Xiong, et al.cells and PTX-resistant BC cells were planted into a 6-well plate, and treated with paclitaxel (PTX, HY-B0015, MCE, New Jersey, USA) for 48 h after transfection. Cell apoptosis rate was analyzed by flow cytometry

(16) Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effectsInternational Journal of OncologyNovember 26, 2025Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, et al.MedChemExpress) was dissolved in DMSO to prepare a 100 mM stock solution. Paclitaxel (PTX; cat. no. HY-B0015; MedChemExpress) was dissolved in DMSO to prepare a 100 mM stock solution. Cisplatin (DDP; cat. no.

(17) Quercetin inhibits gastric cancer cell proliferation and migration and is associated with the suppression of the IDO1-Kynurenine-AhR axisBMC CancerNovember 25, 2025Manqin Zhu, Qinghua Hu, Yanxiang Lu, Qingyi Xu, Hui Huang, Ka Chen, Xia Shuai, Yunjuan Wang, Jinshi Huang, Zhibin Guo02–024-1ACS, BI), DMSO(D2650,Sigma-Aldrich), cisplatin (HY-17394, MCE), quercetin (HY-18085, MCE), paclitaxel (HY-B0015, MCE), and CCK-8 cell proliferation assay kit (KGA317, KeyGEN BioTECH) were obtained commercially. Experimental

(18) Efferocytosis‐Driven Polyamine Metabolism in Macrophages Enhances Cancer Stem Cell Enrichment after Chemotherapy in Ovarian CancerAdvanced ScienceNovember 21, 2025Wenhan Li, Feiquan Ying, Xinkai Pang, Qiulei Wu, Guoqing Li, Lin Huang, Jiayu Xin, Xiaoli Liu, Pan Liu, Xiaohan Xu, et al.intraperitoneal injections of vehicle, cisplatin (3 mg kg−1, MCE, HY‐17394), paclitaxel (10 mg kg−1, MCE, HY‐B0015), or a combination of cisplatin (3 mg kg−1) and paclitaxel (10 mg kg−1) were administered every 3 days.

(19) Oligoclonal tumor-specific CD8 T-cell revival and IRE1α/XBP1-GDF15-mediated immunosuppressive niches determine neoadjuvant chemoimmunotherapy efficacy in cervical cancerJournal for ImmunoTherapy of CancerNovember 19, 2025Guangxu Cao, Yuhan Wang, Huimin Zeng, Yong Zhi, Yi Guo, Mengting Xu, Yetian Ruan, Ying Wang, Yuhang Xiao, Jianqiao Lu, et al.MCE, cat No. HY-19707) were formulated in sterile saline, while paclitaxel (15 mg/kg, MCE, cat No. HY-B0015) was prepared in a vehicle containing 1% DMSO, 4% PEG300, 0.5% Tween-80, and 94.5% saline. Chemotherapeutic

(20) NRG1/PDGFC loop between fibroblasts and cancer cells drives paclitaxel resistance via ferroptosis suppression in breast cancerCell Death DiscoveryNovember 10, 2025Wan-Li Duan, Xue-Jie Wang, Li-Hui Gu, Ai Guo, Yi-Yue Ding, Ping Lin, Bao-Gang Zhangprocedure described above. Drug treatment PDGFC recombinant protein (HY-P7279), Paclitaxel (PTX, HY-B0015), ARQ 751 trihydrochloride (HY-137458A), Erastin (HY-15763), Nigericin (HY-127019), Hydroxyurea (HY-B0313),

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Paclitaxel from MedChemExpress

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Paclitaxel from MedChemExpress

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