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Protein Biochemistry
Chemicals and Reagents
DBeQ
DBeQ from MedChemExpress
Be the first to write a review!
Citations:
(6)
Supplier Page
Supplier Page from
MedChemExpress for
DBeQ
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Description
DBeQ is a selective, potent, reversible, and ATP-competitive
p97
inhibitor, with an
IC
50
value of 1.5 µM and 1.6 µM for p97(wt) and p97(C522A), respectively; DBeQ also inhibits
Vps4
with an
IC
50
of 11.5 µM
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
DBeQ
Company
MedChemExpress
Price
$87.00
Supplier Page
View Company Product Page
Catalog Number
HY-15945
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
98.79%
Type
Chemical
Molecular Weight
340.42
Formula
C₂₂H₂₀N₄
Research Area
Cancer
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (6)
(1)
Coronaviral nsp6 hijacks ERAD machinery to facilitate lipolysis and supply membrane components for DMV growth
Nature Communications
November 18, 2025
Shu-Rui Liu, Yuzheng Zhou, Jinwei Li, Zhaohuan Wang, Yu Ye, Jiafan Miao, Keda Shi, Birong Zheng, Binbin Ding, Jian Pan,
et al.
6-8-week-old C57/BL6 female
mice
were used for in vivo
viral infection
.
CB-5083
(
MCE
,
HY-12861
) and
DBeQ
(
MCE
,
HY-15945
) were prepared in 5% DMSO and then diluted in 0.5% methyl cellulose or 40%
PEG300
with 5%
Tween-80
,
(2)
DBeQ derivative targets vacuolar protein sorting 4 functions in cancer cells and suppresses tumor growth in mice
The Journal of Pharmacology and Experimental Therapeutics
April 1, 2025
Kevin A. Fundora, Yan Zhuang, Kouta Hamamoto, Guifang Wang, Longgui Chen, Tatsuya Hattori, Xinwen Liang, Lei Bao, Venugopal Vangala, Fang Tian,
et al.
(
MedChemExpress
;
HY-12861
), chloroquine diphosphate (CQ;
Sigma-Aldrich
;
C6628
),
DBeQ
(
MedChemExpress
;
HY-15945
), Dulbecco’s modified Eagle’s medium (high glucose) with sodium pyruvate, without amino acids (
starvation
(3)
The protein segregase VCP/p97 promotes host antifungal defense via regulation of SYK activation
PLOS Pathogens
October 29, 2024
Zhugui Shao, Li Wang, Limin Cao, Tian Chen, Xin-Ming Jia, Wanwei Sun, Chengjiang Gao, Hui Xiao
NMS-873
(
S7285
), PRT (
S7738
) were purchased from
Selleck
.
PP2
(
HY-13805
),
CB-5083
(
HY-12861
),
DBeQ
(
HY-15945
),
ML240
(
HY-19795
) and
TPI-1
(
HY-100463
) were purchased from
MCE
. Mouse anti-V5 (66007-I-lg) was from
(4)
CircHIPK3 negatively regulates autophagy by blocking VCP binding to the Beclin 1 complex in bladder cancer
Discov Oncol
June 3, 2023
Wang C, Liu T, Wang J, Cheng C, Zhang Z, Zhang J, Huang H, Li Y.
each. Acetone was applied twice, each time for 15 min, and then removed. Chemical reagents
DBeQ
(
HY-15945
) was purchased from
MCE
(China).
Chromatin
isolation by
RNA purification
(CHIRP) The specific biotin
(5)
The AAA ATPase Vps4 Plays Important Roles in Candida albicans Hyphal Formation and is Inhibited by DBeQ
Mycopathologia
June 1, 2016
Zhang Y, Li W, Chu M, Chen H, Yu H, Fang C, Sun N, Wang Q, Luo T, Luo K,
et al
.
(6)
Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways
Proceedings of the National Academy of Sciences of the United States of America
March 22, 2011
Chou TF, Brown SJ, Minond D, Nordin BE, Li K, Jones AC, Chase P, Porubsky PR, Stoltz BM, Schoenen FJ,
et al
.
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DBeQ from MedChemExpress
Supplier Page
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$87.00
Product Specs
Company Info
Citations
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