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Protein Biochemistry
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Verdiperstat
Verdiperstat from MedChemExpress
Be the first to write a review!
Citations:
(6)
Supplier Page
Supplier Page from
MedChemExpress for
Verdiperstat
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Description
Verdiperstat (AZD3241) is a selective, irreversible and orally active
myeloperoxidase (MPO)
inhibitor, with an
IC
50
of 630 nM, and can be used in the research of neurodegenerative brain disorders
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Verdiperstat
Company
MedChemExpress
Price
$117.00
Supplier Page
View Company Product Page
Catalog Number
HY-17646
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.85%
Formula
C11H15N3O2S
Research Area
Neurological Disease
Type
Chemical
Molecular Weight
253.32
Quantity
10 mM * 1 mL
Molecule Name
Verdiperstat
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (6)
(1)
Hydroxychloroquine reduces metastatic tumor burden in pancreatic adenocarcinoma through myeloperoxidase inhibition
J Inflamm (Lond)
August 12, 2025
Britney Niemann, Pavan Rao, Quinn Hopen, Kaitlyn Landreth, Angisha Basnet, Werner Geldenhuys, Tracy W. Liu, Brian A. Boone
replaced every three days. Regular drinking water was given to control
mice
.
Verdiperstat
(
MedChemExpress
#
HY-17646
), a known MPO inhibitor, was given via daily
intraperitoneal injection
at 1.37 mg in 300 µL.
Verdiperstat
(2)
Complex I inhibition combined with TLR activation in the breast tumor microenvironment educates cytotoxic neutrophils
Sci Adv
July 11, 2025
John Heath, Ryuhjin Ahn, Valerie Sabourin, Young Kyuen Im, Sabrina Rezzara Richard, Alva Annett, Caitlynn Mirabelli, Samantha Worme, Sarah M. Maritan, Caitlyn Mourcos,
et al.
in vivo use, 5 μg was administered every 2 days in 10% solution diluted with saline.
Verdiperstat
(
HY-17646
,
MedChemExpress
) was dissolved in DMSO at a concentration of 50 mg/ml and then diluted
1:10
with saline,
(3)
The PAD4 inhibitor GSK484 diminishes neutrophil extracellular trap in the colon mucosa but fails to improve inflammatory biomarkers in experimental colitis
Bioscience Reports
June 27, 2025
Kangzhe Xie, Jordan Hunter, Aaron Lee, Gulfam Ahmad, Paul K. Witting, Tamara Ortiz-Cerda
synthetic MPO inhibitor, AZD3241 (also known as
Verdiperstat
), was purchased from
MedChemExpress
(Cat#
HY-17646
), whilst PAD4
inhibitor
,
GSK484
, was acquired from a commercial source (
Abcam
, Sydney Australia, Cat#
(4)
Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease
Brain : a journal of neurology
September 1, 2015
Jucaite A, Svenningsson P, Rinne JO, Cselényi Z, Varnäs K, Johnström P, Amini N, Kirjavainen A, Helin S, Minkwitz M,
et al
.
(5)
Development of rapid multistep carbon-11 radiosynthesis of the myeloperoxidase inhibitor AZD3241 to assess brain exposure by PET microdosing
Nuclear medicine and biology
June 1, 2015
Johnström P, Bergman L, Varnäs K, Malmquist J, Halldin C, Farde L.
(6)
[Spinal muscular atrophy]
Ryoikibetsu shokogun shirizu
January 1, 2001
Saito K.
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Verdiperstat from MedChemExpress
Supplier Page
View Company Product Page
$117.00
Product Specs
Company Info
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