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ROCK inhibitor-2
ROCK inhibitor-2 from MedChemExpress
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Citations:
(3)
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ROCK inhibitor-2
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Description
ROCK inhibitor-2 (compound 6) is a selective dual inhibitor of ROCK1 and ROCK2, with
IC
50
values of 160 nM and 21 nM, respectively. ROCK inhibitor-2 inhibits pMYPT1 with
IC
50
of 75 nM. ROCK inhibitor-2 exhibits antitumor activity
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
ROCK inhibitor-2
Company
MedChemExpress
Price
$132.00
Supplier Page
View Company Product Page
Catalog Number
HY-119937
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.92%
Formula
C21H20N2O2
Research Area
Inflammation/Immunology; Cardiovascular Disease; Cancer
Type
Chemical
Molecular Weight
332.40
Quantity
10 mM * 1 mL
Molecule Name
ROCK inhibitor-2
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (3)
(1)
FOXO-regulated DEAF1 controls muscle regeneration through autophagy
Autophagy
December 1, 2024
Kah Yong Goh, Wen Xing Lee, Sze Mun Choy, Gopal Krishnan Priyadarshini, Kenon Chua, Qian Hui Tan, Shin Yi Low, Hui San Chin, Chee Seng Wong, Shu-Yi Huang,
et al.
Production, MD004A-UK], FGF2/
bFGF
(5 ng/ml;
Gibco
,
PHG0021
), 10 µM ROCK inhibitor (
MedChemExpress
,
HY119937
), 1% sodium pyruvate (
Lonza
,
BE13-115E
) and 1% penicillin-streptomycin). The cells were pre-plated overnight.
(2)
3D-printing magnesium-polycaprolactone loaded with melatonin inhibits the development of osteosarcoma by regulating cell-in-cell structures
Journal of nanobiotechnology
September 4, 2021
Zhang W, Zhao W, Li Q, Zhao D, Qu J, Yuan Z, Cheng Z, Zhu X, Zhuang X, Zhang Z.
University Ethics Committee (No. EC-2018-KS-058). Reagents Pentanoic acid (HY-N6056),
ROCK inhibitor-2
(
HY-119937
),
S26131
(
HY-122136
) and
7-Desmethyl-agomelatine
(
HY-133113
) were obtained from Med Chem Express (
MCE
,
(3)
Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based Drug Design
Journal of medicinal chemistry
December 27, 2018
Hobson AD, Judge RA, Aguirre AL, Brown BS, Cui Y, Ding P, Dominguez E, DiGiammarino E, Egan DA, Freiberg GM,
et al
.
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ROCK inhibitor-2 from MedChemExpress
Supplier Page
View Company Product Page
$132.00
Product Specs
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