BGP-15 from MedChemExpress

Product Specs
ItemBGP-15
CompanyMedChemExpress
Price $66.00Supplier Page View Company Product Page
Catalog NumberHY-100828
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity98.0%
TypeChemical
Molecular Weight351.27
FormulaC₁₄H₂₄Cl₂N₄O₂
Research AreaCardiovascular Disease; Cancer

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(1) Biochemical Insights into the Effects of a Small Molecule Drug Candidate on Imatinib-Induced Cardiac InflammationInt J Mol SciJuly 11, 2025Renáta Szabó, Denise Börzsei, András Nagy, Viktória Kiss, Zoltán Virág, Gyöngyi Kis, Nikoletta Almási, Szilvia Török, Médea Veszelka, Mária Bagyánszki, et al.9/group), imatinib (60 mg/kg daily once per os for 14 consecutive days) was co-administered with BGP-15 (HY-100828, MedChemExpress, Monmouth Junction, NJ, USA) at the dose of 10 mg/kg once daily per os. For this group,

(2) BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal MuscleThe American journal of pathologyDecember 1, 2016Kennedy TL, Swiderski K, Murphy KT, Gehrig SM, Curl CL, Chandramouli C, Febbraio MA, Delbridge LM, Koopman R, Lynch GS.

(3) The chaperone co-inducer BGP-15 alleviates ventilation-induced diaphragm dysfunctionScience translational medicineAugust 3, 2016Salah H, Li M, Cacciani N, Gastaldello S, Ogilvie H, Akkad H, Namuduri AV, Morbidoni V, Artemenko KA, Balogh G, et al.

(4) The small-molecule BGP-15 protects against heart failure and atrial fibrillation in miceNature communicationsDecember 9, 2014Sapra G, Tham YK, Cemerlang N, Matsumoto A, Kiriazis H, Bernardo BC, Henstridge DC, Ooi JY, Pretorius L, Boey EJ, et al.

(5) Improvement of insulin sensitivity by a novel drug candidate, BGP-15, in different animal studiesMetabolic syndrome and related disordersMarch 1, 2014Literáti-Nagy B, Tory K, Peitl B, Bajza Á, Korányi L, Literáti-Nagy Z, Hooper PL, Vígh L, Szilvássy Z.

(6) BGP-15, a PARP-inhibitor, prevents imatinib-induced cardiotoxicity by activating Akt and suppressing JNK and p38 MAP kinasesMolecular and cellular biochemistryJune 1, 2012Sarszegi Z, Bognar E, Gaszner B, Kónyi A, Gallyas F Jr, Sumegi B, Berente Z.

(7) BGP-15, a nicotinic amidoxime derivate protecting heart from ischemia reperfusion injury through modulation of poly(ADP-ribose) polymeraseBiochemical pharmacologyApril 15, 2000Szabados E, Literati-Nagy P, Farkas B, Sumegi B.

(8) A new short practical quality of life questionnaire for use in head and neck oncology outpatient clinicsClinical otolaryngology and allied sciencesDecember 1, 1998Young PE, Beasley NJ, Houghton DJ, Husband DJ, Currie M, Chislett B, Jones AS.

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BGP-15 from MedChemExpress

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BGP-15 from MedChemExpress

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