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CASIN
CASIN from MedChemExpress
Be the first to write a review!
Citations:
(8)
Supplier Page
Supplier Page from
MedChemExpress for
CASIN
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Description
CASIN is a selective
GTPase Cdc42
inhibitor with an
IC
50
of 2 uM. CASIN can be used for the research of cancer
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
CASIN
Company
MedChemExpress
Price
$101.00
Supplier Page
View Company Product Page
Catalog Number
HY-12874
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.89%
Formula
C20H22N2O
Research Area
Cancer
Type
Chemical
Molecular Weight
306.40
Quantity
10 mM * 1 mL
Molecule Name
CASIN
Add to Compare List
MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (8)
(1)
Scalable quantification of dynamic subcellular spatial organization in single cells across tissues
ResearchSquare
July 2, 2026
Soumen Loeffler, Shalmali Pendse, Shalmali Harrell, Jessica Harrell, Jessica Loeffler
MemGlow590 at 0.04 μM (
1:500
dilution) (#MG03, Cytoskeleton Inc). Cells were incubated with 2.5μM
CASIN
(
HY-12874
,
MedChemExpress
) to perturb polarity and actin dynamics without fully abolishing F-actin activity, then
(2)
CDC42-effector interaction inhibitors alter patterns of vessel arborization in skin and tumors in vivo
iScience
July 18, 2025
Linh M. Vuong, Stephanie Hachey, Jessica Shiu, Danny F. Xie, Noel Salvador, Nicoletta Brindani, Sine Mandrup Bertozzi, Maria Summa, Rosalia Bertorelli, Andrea Armirotti,
et al.
(ABT869),
MedChemExpress
,Cat#
HY-50751
Vemurafenib (PLX4032),SellekChem,Cat# S1267
CASIN
,
MedChemExpress
,Cat#
HY-12874
,, Deposited data,Deposited data,Deposited data ,, RNA sequence data,This paper,GEO: GSE298488 ,,
Experimental models
(3)
TRPM2 channels mediate ROS-induced actin remodeling and cell migration of prostate cancer cells
BMC Cancer
May 28, 2025
Pengwei Qi, Jingting Zhao, Hongtian Zhang, Xingyu Liu, Qing You, Jianguo Niu, Xiangming Ye, Fangfang Li
(
HY-100545
),
TPEN
(
HY-100202
),
Econazole
(
HY-B0885
),
Zinc Pyrithione
(
HY-B0572
), A23187 (
HY-N6687
),
CASIN
(
HY-12874
),
NSC 23766
(
HY-15723
) were from
MedChemExpress
. As palmitic acid is insoluble in water, it is commonly
(4)
pTINCR microprotein promotes epithelial differentiation and suppresses tumor growth through CDC42 SUMOylation and activation
Nat Commun
November 11, 2022
Olga Boix, Marion Martinez, Santiago Vidal, Marta Giménez-Alejandre, LluÃs Palenzuela, Laura Lorenzo-Sanz, Laura Quevedo, Olivier Moscoso, Jorge Ruiz-Orera, Pilar Ximénez-Embún,
et al.
MedChemExpress
) was added at 10 µM for a minimum of 16 h. For CDC42-GTP inhibition,
CASIN
and
ML141
(#
HY-12874
and #
HY-12755
respectively,
MedChemExpress
) were added at 5 µM for 2 h minimum prior to additional treatments.
RNA-Seq
(5)
Uterus globulin associated protein 1 (UGRP1) binds podoplanin (PDPN) to promote a novel inflammation pathway during Streptococcus pneumoniae infection
Clinical and translational medicine
June 1, 2022
Han L, Zhang F, Liu Y, Yu J, Zhang Q, Ye X, Song H, Zheng C, Han B.
and recombinant proteins"
Narciclasine
,
MCE
,Cat#
HY‐16563
CCG‐1423
,
MCE
,Cat#
HY‐13991
CASIN
,
MCE
,Cat#
HY‐12874
1A‐116
,
MCE
,Cat#
HY‐104064
MBQ‐167
,
MCE
,Cat#
HY‐112842
IRAK‐1‐4 Inhibitor I
,
MCE
,Cat#
HY‐13329
Takinib
,
MCE
,Cat#
(6)
Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation
Cell stem cell
May 4, 2012
Florian MC, Dörr K, Niebel A, Daria D, Schrezenmeier H, Rojewski M, Filippi MD, Hasenberg A, Gunzer M, Scharffetter-Kochanek K,
et al
.
(7)
Donor-specific transfusion and antibody response
Lancet (London, England)
March 28, 1987
McMillan MA, Briggs JD, Junor BJ, MacSween RN, Sandilands GP.
(8)
Rational Targeting of Cdc42 Overcomes Drug Resistance of Multiple Myeloma
Frontiers in oncology
January 1, 0001
"Nguyen P, Chakrabarti J, Li Y, Kalim KW, Zhang M, Zhang L, Zheng Y, Guo F."
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CASIN from MedChemExpress
Supplier Page
View Company Product Page
$101.00
Product Specs
Company Info
Citations
Reviews
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