RK-24466 from MedChemExpress | Biocompare.com

Be the first to write a review!

Citations:

Supplier Page from
MedChemExpress for
RK-24466

Description

RK-24466 (KIN 001-51) is a potent and selective Lck inhibitor; inhibits Lck (64-509) and LckCD isoforms with IC₅₀s of less than 1 and 2 nM, respectively

Product Specs
ItemRK-24466
CompanyMedChemExpress
Price $198.00Supplier Page View Company Product Page
Catalog NumberHY-108318
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.91%
TypeChemical
Molecular Weight370.45
FormulaC₂₃H₂₂N₄O
Research AreaInflammation/Immunology; Cardiovascular Disease

Add to Compare List

MedChemExpress

MedChemExpress

1 Deer Park Drive, Suite F

MONMOUTH JUNCTION, NJ 08852

United States

Phone: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910

Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com

Company Profile

Website: medchemexpress.com

(1) 7-cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d] pyrimidin-4-ylamine inhibits the proliferation and migration of vascular smooth muscle cells by suppressing ERK and Akt pathwaysEuropean journal of pharmacologyMarch 5, 2017Seo HH, Kim SW, Lee CY, Lim KH, Lee J, Lim S, Lee S, Hwang KC.

(2) Pyrrolo[2,3-d]pyrimidines containing an extended 5-substituent as potent and selective inhibitors of lck IIBioorganic & medicinal chemistry lettersOctober 2, 2000Burchat AF, Calderwood DJ, Hirst GC, Holman NJ, Johnston DN, Munschauer R, Rafferty P, Tometzki GB.

(3) Pyrrolo[2,3-d]pyrimidines containing an extended 5-substituent as potent and selective inhibitors of lck IBioorganic & medicinal chemistry lettersOctober 2, 2000Arnold LD, Calderwood DJ, Dixon RW, Johnston DN, Kamens JS, Munschauer R, Rafferty P, Ratnofsky SE.

(4) Combined neutrophil and T-cell deficiencyThe American journal of medicineAugust 1, 1983Silverman E, Bargman J.

Be the First to Write a Review!