SL327 from MedChemExpress

Product Specs
ItemSL327
CompanyMedChemExpress
Price $44.00Supplier Page View Company Product Page
Catalog NumberHY-15437
Quantity10 mM * 1 mL
Research AreaCancer
FormulaC₁₆H₁₂F₃N₃S
Molecular Weight335.35
TypeChemical
Purity99.57%
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting

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(1) Mesenchymal stem cell-derived extracellular vesicles alleviate autism by regulating microglial glucose metabolism reprogramming and neuroinflammation through PD-1/PD-L1 interactionJ NanobiotechnologyMarch 11, 2025Qian Qin, Linlin Fan, Xin Zeng, Danyang Zheng, Han Wang, Mengyue Li, Yutong Jiang, Hui Wang, Hao Liu, Shengjun Liang, et al.HY-N0003, MedChemExpress) to the treatment with MSC-EVs. We also applied the ERK inhibitor SL327 (10 µM, HY-15437, MedChemExpress) to treat with MSC-EVs and PD-1 Ab. To explore the effect of PD-L1 of MSC-EVs on microglia

(2) Epileptic seizures induced by pentylenetetrazole kindling accelerate Alzheimer-like neuropathology in 5×FAD miceFrontiers in pharmacologyJanuary 1, 2024Zou Y, Wang C, Li H, Zhong M, Lin J, Hu Y, Chen Z, Gan CL.methods Materials PTZ was purchased from MilliporeSigma (St. Louis, MO, United States), and the ERK inhibitor SL327 (HY-15437) and CBZ (HY-B0246) were obtained from MedChemExpress (NJ, United States). Animals Male wild-type

(3) Activation of MEK1/2/Nrf-2 Signaling Pathway by Epstein-Barr Virus-Latent Membrane Protein 1 Enhances Autophagy and Cisplatin Resistance in T-Cell LymphomaAnalytical Cellular PathologyJune 18, 2021Xintao Jia, Qiuyu He, Mei Zeng, Yuhua Chen, Yan LiuJunction, NJ, USA), Mitogen-activated protein kinase 1/2- (MEK1/2-) specific inhibitor SL327 (20 ng/mL, #HY-15437, MedChemExpress), or the control DMSO for 24 h. The cells were collected for subsequent experiments. 2.2.

(4) M-Calpain Activation Facilitates Seizure Induced KCC2 Down RegulationFrontiers in molecular neuroscienceJanuary 1, 2018Wan L, Ren L, Chen L, Wang G, Liu X, Wang BH, Wang Y.min, before intraperitoneal injection with either MDL-28170 (#ab145601, abcam, 50 mg/kg) or SL-327 (#HY-15437, MCE, 50 mg/kg) or equal volume vehicle (DMSO) in different groups as pre-treatment. Thirty minutes

(5) Current Development Status of MEK InhibitorsMolecules (Basel, Switzerland)September 26, 2017Cheng Y, Tian H.

(6) A necessity for MAP kinase activation in mammalian spatial learningLearning & memory (Cold Spring Harbor, N.Y.)September 1, 1999Selcher JC, Atkins CM, Trzaskos JM, Paylor R, Sweatt JD.

(7) "[So-called ""spontaneous"" lesions of the popliteal artery]"Minerva cardioangiologicaNovember 1, 1997Miani S, De Monti M, Boneschi M, Giordanengo F.

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SL327 from MedChemExpress

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