PFE-360 from MedChemExpress

Product Specs
ItemPFE-360
CompanyMedChemExpress
Price $231.00Supplier Page View Company Product Page
Catalog NumberHY-120085
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.48%
TypeChemical
Molecular Weight308.34
FormulaC₁₆H₁₆N₆O
Research AreaNeurological Disease

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(1) Targeting leucine-rich repeat kinase 2 overcomes resistance to oncolytic herpes simplex virus-based therapies in glioblastomaNature CommunicationsFebruary 28, 2026Yaning Qin, Zhiqi Liang, Mengqin Yu, Nanqian Lin, Naizhen Wang, Xuanke Huang, Shi Chen, Qun Peng, Yanhua Lin, Heqin Wang, et al.MLi-2 (MedChemExpress, HY-100411), Fludarabine (MedChemExpress, HY-B0069), PFE-360 (MedChemExpress, HY-120085), BX795 (TopScience, T1830), Phosphatase inhibitor cocktail III (TopScience, C0004), Protease inhibitor cocktail

(2) A potential patient stratification biomarker for Parkinson´s disease based on LRRK2 kinase-mediated centrosomal alterations in peripheral blood-derived cellsnpj Parkinson's DiseaseJanuary 8, 2024Yahaira Naaldijk, Belén Fernández, Rachel Fasiczka, Elena Fdez, Coline Leghay, Ioana Croitoru, John B. Kwok, Yanisse Boulesnane, Amelie Vizeneux, Eugenie Mutez, et al.GNE-7915 (MedChemExpress, HY-18163), PF-06447475 (MedChemExpress, HY-12477) and PF-360 (MedChemExpress, HY-120085) were added at the indicated concentrations for 2 h before processing for immunocytochemistry where

(3) High-content phenotyping of Parkinson's disease patient stem cell-derived midbrain dopaminergic neurons using machine learning classificationStem cell reportsOctober 11, 2022Vuidel A, Cousin L, Weykopf B, Haupt S, Hanifehlou Z, Wiest-Daesslé N, Segschneider M, Lee J, Kwon YJ, Peitz M, et al.(MedChemExpress, #HY-18163), 0.1 μM MLi-2 (MedChemExpress, #HY-100411), 0.1 μM PFE-360 (MedChemExpress, #HY-120085), and 0.1 μM rotenone (Sigma, #R8875) was performed at 36 DIV for 24 h until 37 DIV. Treatment with

(4) Parkinson's disease-like burst firing activity in subthalamic nucleus induced by AAV-α-synuclein is normalized by LRRK2 modulationNeurobiology of diseaseAugust 1, 2018Andersen MA, Christensen KV, Badolo L, Smith GP, Jeggo R, Jensen PH, Andersen KJ, Sotty F.

(5) PFE-360-induced LRRK2 inhibition induces reversible, non-adverse renal changes in ratsToxicologyFebruary 15, 2018Andersen MA, Wegener KM, Larsen S, Badolo L, Smith GP, Jeggo R, Jensen PH, Sotty F, Christensen KV, Thougaard A.

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PFE-360 from MedChemExpress

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PFE-360 from MedChemExpress

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