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Protein Biochemistry
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Raltegravir
Raltegravir from MedChemExpress
Be the first to write a review!
Citations:
(12)
Supplier Page
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MedChemExpress for
Raltegravir
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Description
Raltegravir is a potent
integrase (IN)
inhibitor, used to treat HIV infection
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Raltegravir
Company
MedChemExpress
Price
$85.00
Supplier Page
View Company Product Page
Catalog Number
HY-10353
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.93%
Type
Chemical
Molecular Weight
444.42
Molecule Name
Raltegravir
Formula
C20H21FN6O5
Research Area
Infection; Cancer
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (12)
(1)
BACH2 promotes seeding and establishment of long-lived HIV-1 reservoir in memory CD4+ T cells
Cell Reports Medicine
September 16, 2025
Hongbo Gao, Yuhao Li, Ritudwhaj Tiwari, Marilia Pinzone, Xiwen Qin, Kolin M. Clark, Sara K. Nicholson, Tony Yao, Kelly Rome, Michael Scaglione,
et al.
(PHA-L),Sigma,11249738001 Enfuvirtide (T-20),
MedChemExpress
,
HY-P0052
Raltegravir
(RAL),
MedChemExpress
,
HY-10353
Recombinant Cas9 protein,IDT,1081059
Random Primers
,
Invitrogen
,48190–011
ProtoScript II Reverse Transcriptase
,
NEB
,
M0368
"
RNase Inhibitor, Murine
(2)
The nuclear localization signal of CPSF6 governs post-nuclear import steps of HIV-1 infection
PLOS Pathogens
January 17, 2025
Nicholas Rohlfes, Rajalingam Radhakrishnan, Parmit K. Singh, Gregory J. Bedwell, Alan N. Engelman, Adarsh Dharan, Edward M. Campbell
expression. CsA was purchased from Sigma-Aldrich. RAL was purchased from
MedChemExpress
(Catalogue no.
HY-10353
). Hoechst was purchased from
ImmunoChemistry Technologies
(Catalogue no. 639).
Western blot
Cell lysates
(3)
Serendipitous Identification of Azine Anticancer Agents Using a Privileged Scaffold Morphing Strategy
Molecules
March 24, 2024
Silvia Cesarini, Ilaria Vicenti, Federica Poggialini, Silvia Filippi, Eleonora Mancin, Lia Fiaschi, Elisa De Marchi, Federica Giammarino, Chiara Vagaggini, Bruno Mattia Bizzarri,
et al.
Euroclone S.p.A. (Milan, Italy). SOF (
MCE
® cat.
HY-15005
), REM (
MCE
® cat.
HY-104077
) and RAL (
MCE
® cat.
HY-10353
), used as reference compounds, were purchased from MedChem Express (https://www.medchemexpress.com,
(4)
Spastin is required for human immunodeficiency virus-1 efficient replication through cooperation with the endosomal sorting complex required for transport (ESCRT) protein
Virologica Sinica
June 1, 2023
Shen W, Liu C, Hu Y, Ding Q, Feng J, Liu Z, Kong X.
5′-TGCATGGGTAAAAGTAGTAGAAGAGA-3′; reverse, 5′-TGATAATGCTGAAA ACATGGGTA-3′).
HIV-1 integrase inhibitor
raltegravir (
HY-10353
,
MedChemExpress
, New Jersey, USA) was used as a positive control. 2.7 Release efficiency Cells were
(5)
Privileged Scaffold Decoration for the Identification of the First Trisubstituted Triazine with Anti-SARS-CoV-2 Activity
Molecules
December 12, 2022
Silvia Cesarini, Ilaria Vicenti, Federica Poggialini, Massimiliano Secchi, Federica Giammarino, Ilenia Varasi, Camilla Lodola, Maurizio Zazzi, Elena Dreassi, Giovanni Maga,
et al.
half-maximal cytotoxic concentration (CC50).
Remdesivir
(
MCE
® cat.
HY-104077
) and
Raltegravir
(
MCE
® cat.
HY-10353
), used as reference compounds for
SARS-CoV-2
and
HIV-1
antiviral tests, respectively, were purchased
(6)
Effective Drugs Against Severe Fever With Thrombocytopenia Syndrome Virus in an in vitro Model
Frontiers in Medicine
March 31, 2022
Mi-Seon Bang, Choon-Mee Kim, Dong-Min Kim, Na Ra Yun
(HY-13997), oseltamivir (HY-13318), penciclovir (HY-17424), perindopril salt (HY-B0130A), raltegravir (
HY-10353
), remdesivir (GS-5734,
HY-104077
), rilpivirine (
HY-10574
), ritonavir (
HY-90001
), simeprevir (
HY-10241
),
(7)
Combined Medication of Antiretroviral Drugs Tenofovir Disoproxil Fumarate, Emtricitabine, and Raltegravir Reduces Neural Progenitor Cell Proliferation In Vivo and In Vitro
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology
December 1, 2017
Xu P, Wang Y, Qin Z, Qiu L, Zhang M, Huang Y, Zheng JC.
(8)
Divalent metals and pH alter raltegravir disposition in vitro
Antimicrobial agents and chemotherapy
June 1, 2012
Moss DM, Siccardi M, Murphy M, Piperakis MM, Khoo SH, Back DJ, Owen A.
(9)
Structural and functional analyses of the second-generation integrase strand transfer inhibitor dolutegravir (S/GSK1349572)
Molecular pharmacology
October 1, 2011
Hare S, Smith SJ, Métifiot M, Jaxa-Chamiec A, Pommier Y, Hughes SH, Cherepanov P.
(10)
Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance
Proceedings of the National Academy of Sciences of the United States of America
November 16, 2010
Hare S, Vos AM, Clayton RF, Thuring JW, Cummings MD, Cherepanov P.
(11)
Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: a basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy
Retrovirology
March 16, 2010
Lewis MG, Norelli S, Collins M, Barreca ML, Iraci N, Chirullo B, Yalley-Ogunro J, Greenhouse J, Titti F, Garaci E,
et al
.
(12)
Raltegravir: the first HIV type 1 integrase inhibitor
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
April 1, 2009
Hicks C, Gulick RM.
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Raltegravir from MedChemExpress
Supplier Page
View Company Product Page
$85.00
Product Specs
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