ISA-2011B from MedChemExpress

Product Specs
ItemISA-2011B
CompanyMedChemExpress
Price $319.00Supplier Page View Company Product Page
Catalog NumberHY-16937
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.85%
TypeChemical
Molecular Weight423.85
FormulaC₂₂H₁₈ClN₃O₄
Research AreaCancer

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(1) Membrane composition-dependent patterning of Rho and F-actin in an artificial cell cortexMolecular Biology of the CellApril 1, 2026Gregory J. Schwarz, Joanna R. Suber, Devika Andhare, Michael J. Ragusa, Jennifer Landino4-kinase PI4KA inhibitor, MedChemExpress, HY-125118) and ISA-2011B (PIP5K1α inhibitor, MedChemExpress, HY-16937) were resuspended in DMSO and stored at −80°C. MDE was treated with 30 µM GSK-A1 and 20 µM ISA-2011B,

(2) Membrane composition-dependent patterning of Rho and F-actin in an artificial cell cortexMol Biol CellMarch 11, 2026Gregory J. Schwarz, Joanna R. Suber, Devika Andhare, Michael J. Ragusa, Jennifer Landino4-kinase PI4KA inhibitor, MedChemExpress, HY-125118) and ISA-2011B (PIP5K1α inhibitor, MedChemExpress, HY-16937) were resuspended in DMSO and stored at −80°C. MDE was treated with 30 µM GSK-A1 and 20 µM ISA-2011B,

(3) Carbon-based quantum dots enhance platelets aggregation through migrasomes biogenesisJournal of NanobiotechnologyJanuary 17, 2026Ang Li, Leiliang ZhangFuGENE HD (E2311, Promega, Madison, WI, USA) according to the manufacturer’s guidelines. ISA2011B (HY-16937), NSC23766 (HY-15723), carbonyl cyanide 3-chlorophenylhydrazone (CCCP) (HY-100941), and filipin complex

(4) PIP5K1A Suppresses Ferroptosis and Induces Sorafenib Resistance by Stabilizing NRF2 in Hepatocellular CarcinomaAdvanced ScienceMay 23, 2025Mengzhou Guo, Sinuo Chen, Jialei Sun, Ruchen Xu, Zhuoran Qi, Jie Li, Lianer Zhou, Yuan Fang, Tianshu Liu, Jinglin Xiaat 37 °C in a humidified incubator (Thermo Fisher Scientific, Waltham, MA) with 5% CO2. ISA‐2011B (HY‐16937), Z‐VAD(OMe)‐FMK (ZVAD; HY‐16658), Necrosulfonamide (Necro; HY‐100573), MG‐132 (HY‐13259), TBHQ (HY‐100489),

(5) Marcks and Marcks-like 1 proteins promote spinal cord development and regeneration in XenopuseLifeDecember 12, 2024Mohamed El Amri, Abhay Pandit, Gerhard SchlosserμM "Chemical compound, drug",m-3M3FBS,TOCRIS,1941,10 μM "Chemical compound, drug",ISA-2011B,MedChemExpress,HY-16937,10 μM "Chemical compound, drug",DMSO,Sigma-Aldrich,D2650,2% Commercial assay or kit,Q5 site-directed mutagenesis kit

(6) Marcks and Marcks-like 1 proteins promote spinal cord development and regeneration in XenopusElifeDecember 12, 2024Mohamed El Amri, Abhay Pandit, Gerhard SchlosserμM "Chemical compound, drug",m-3M3FBS,TOCRIS,1941,10 μM "Chemical compound, drug",ISA-2011B,MedChemExpress,HY-16937,10 μM "Chemical compound, drug",DMSO,Sigma-Aldrich,D2650,2% Commercial assay or kit,Q5 site-directed mutagenesis kit

(7) Bacterial toxins induce non-canonical migracytosis to aggravate acute inflammationCell discoveryNovember 5, 2024Li D, Yang Q, Luo J, Xu Y, Li J, Tao L.Nocodazole (HY-13520), Taxol (HY-N0227), Puromycin (HY-K1057), Doxycycline (HY-N0565B), ISA-2011B (HY-16937), Ly93 (HY-114307), and SMS-IN-1 (HY-102041) were from MedChemExpress. Latruculin A (10010630) and Blasticidin S

(8) Signal Transduction of Transient Receptor Potential TRPM8 Channels: Role of PIP5K, Gq-Proteins, and c-JunMoleculesJune 1, 2024Gerald Thiel, Oliver G. Rösslersubstituted tetrahydroisoquinoline (PubChem CID: 49853637; MedChemExpress, Monmouth, NJ, USA, Cat. No. HY-16937, dissolved in DMSO) at a concentration of 10 μM, or gallein (PubChem CID: 73685, Santa Cruz Biotechnology, Inc

(9) The solute carrier SPNS2 recruits PI(4,5)P2 to synergistically regulate transport of sphingosine-1-phosphateMolecular CellAugust 3, 2023Haiping Tang, Huanyu Li, Dheeraj Prakaash, Conrado Pedebos, Xingyu Qiu, David B. Sauer, Syma Khalid, Katharina Duerr, Carol V. Robinson151882-100G Lipofectamine 2000,Thermo Fisher Scientific,Cat# 11668019 ISA-2011B,MedChemExpress,Cat# HY-16937-5mg UNC3230,Cayman Chemical,Cat# 16401-5 mg-CAY ,, Critical commercial assays,Critical commercial

(10) Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cellsOncotargetSeptember 27, 2016Sarwar M, Semenas J, Miftakhova R, Simoulis A, Robinson B, Gjörloff Wingren A, Mongan NP, Heery DM, Johnsson H, Abrahamsson PA, et al.

(11) The role of PI3K/AKT-related PIP5K1α and the discovery of its selective inhibitor for treatment of advanced prostate cancerProceedings of the National Academy of Sciences of the United States of AmericaSeptember 2, 2014Semenas J, Hedblom A, Miftakhova RR, Sarwar M, Larsson R, Shcherbina L, Johansson ME, Härkönen P, Sterner O, Persson JL.

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ISA-2011B from MedChemExpress

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ISA-2011B from MedChemExpress

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