MSAB from MedChemExpress

Product Specs
ItemMSAB
CompanyMedChemExpress
Price $94.00Supplier Page View Company Product Page
Catalog NumberHY-120697
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.77%
TypeChemical
Molecular Weight305.35
Molecule NameMSAB
FormulaC15H15NO4S
Research AreaCancer

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(1) STRAP promotes hepatocellular carcinoma progression through activation of an STRAP/Wnt-β-catenin/STRAP positive feedback loopiScienceJuly 17, 2026Chunxun Liu, Qiyue Xuan, Zuoming Guo, Xiaoxuan Zhang, Yubao ZhangBS084 Triton X-100,Biosharp,Cat# 10508-1-AP CHX,Sigma Aldrich,Cat# C7698 MSAB,MedChemExpress,Cat# HY-120697 iCRT3,MedChemExpress,Cat# HY-103705 Matrigel,ABW,Cat# BS084 Triton X-100,Biosharp,Cat# 10508-1-AP CHX,Sigma

(2) Stage-specific biomimetic nanoparticles reprogram osteoblast-adipocyte equilibrium for targeted osteoporosis therapyBioact MaterMay 13, 2026Kehan Cai, Zhe Fan, Jun Tan, Wei Cai, Minghang Zhang, Haojie Tang, Jianzhong Xu, Han Lu, Wei He, Qian Xu, et al.perform reverse validation of β-catenin signaling, BMSCs were treated with 5 μM MSAB (MedChemExpress, HY-120697). For Western blot and ALP staining experiments, cells were co-cultured with Ctrl, MSN, SC-MSN, EO-MSN,

(3) Skeletal Stem Cells Rescue Radiation-Induced Osteogenic Precursor Cell Dysfunction via the Wnt/β-Catenin Signaling PathwayDose ResponseApril 7, 2026Huahui Bian, Dongyang Zhao, Haoyu Wang, Hao Huang, Youyou Wang, Weibo Chen, Chang Liu, Yinyin Yang, Anqing Wu, Yulong Liumedium. For pathway inhibition, 10 μmol/L MSAB (MedChemExpress, Monmouth Junction, NJ, USA, Cat. No. HY-120697), a Wnt/β-catenin signaling pathway inhibitor, was added to the co-culture medium. Clonogenic Assay To

(4) Meis1 Negatively Regulates Epithelial-Mesenchymal Transition via Wnt/β-catenin Pathway in Oral Submucous FibrosisInternational Dental JournalApril 1, 2026Jingwen Cai, Jun Chen, Yifan Jiang, Binjie Liua cell model of OSF. MSAB was used to treat HaCaT cells by blocking the Wnt/β-catenin pathway (MCE, HY-120697). Immunohistochemistry The paraffin samples were cut into 4 μm sections. The sections were first dewaxed

(5) Inflamed vessel–anchored release of H 2 across the blood-brain barrier for ischemic stroke neuroprotectionScience AdvancesFebruary 27, 2026Yuanman Yu, Mingjian Fan, Gaoyi Wu, Yongcheng Li, Chao Xia, Wenjiang Ding, Guanglin Li, Qianjun He, Wei Tang, Changsheng LiuSigma-Aldrich, L2630) alone, LPS combined with 5 μM MSAB (a Wnt/β-catenin inhibitor, MedChemExpress, HY-120697), or LPS combined with 20 μM KN-93 (a CaMKII inhibitor, MedChemExpress, HY-15465). Following stimulation,

(6) Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recoveryMolecular Medicine ReportsJanuary 13, 2026Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhaogroup. For the high-dose collagenase + MSAB group (Coln0.2 + MSAB group), 5 mg/kg/day MSAB (cat. no. HY-120697; MedChemExpress) was dissolved in an ultrasonic ice bath and administered intraperitoneally 2 h prior

(7) SPP1 Drives Colorectal Cancer Liver Metastasis and Immunotherapy Resistance by Stimulating CXCL12 Production in Cancer-Associated FibroblastsCancer ResearchOctober 6, 2025Shengde Liu, Zizhen Zhang, Zhenghang Wang, Cheng Liu, Guanghao Liang, Ting Xu, Zhiwei Li, Xiaorui Duan, Gehan Xu, Xujiao Feng, et al.(HY-P70469) proteins were obtained from MedChemExpress. Additionally, the β-catenin inhibitor MSAB (cat. #HY-120697) and the CAF inhibitor talabostat (cat. #HY-13233) were sourced from MedChemExpress. Matrigel was purchased

(8) SPP1 Drives Colorectal Cancer Liver Metastasis and Immunotherapy Resistance by Stimulating CXCL12 Production in Cancer-Associated FibroblastsCancer ResOctober 6, 2025Shengde Liu, Zizhen Zhang, Zhenghang Wang, Cheng Liu, Guanghao Liang, Ting Xu, Zhiwei Li, Xiaorui Duan, Gehan Xu, Xujiao Feng, et al.(HY-P70469) proteins were obtained from MedChemExpress. Additionally, the β-catenin inhibitor MSAB (cat. #HY-120697) and the CAF inhibitor talabostat (cat. #HY-13233) were sourced from MedChemExpress. Matrigel was purchased

(9) Nitrate protects against methotrexate-induced liver injury by activating Wnt/β-catenin Signaling in miceToxicol Res (Camb)July 30, 2025Xin Wen, Ying Liu, Chunmei Zhang, Jinsong Wang, Guangyong Sun, Dong Zhang, Songlin Wang, Shaorong Li(HY-14519, MedChemExpress, NJ, United States), MSAB (methyl 3-{[(4-methylphenyl) sulfonyl] amino} benzoate; HY-120697, MedChemExpress, NJ, United States) and NIC (HY-B0341, MedChemExpress, NJ, United States) were purchased

(10) Isoleucyl-tRNA synthetase 2 promotes pancreatic ductal adenocarcinoma proliferation and metastasis by stabilizing β-cateninGenes & DiseasesMay 1, 2025Yixun Jin, Xinyang Huang, Zhuoxin Wang, Berik Kouken, Qi Wang, Lifu WangCycloheximide (CHX), MG-132, and MSAB were purchased from MedChemExpress (cat. no. HY-12320, HY-13259, and HY-120697, respectively; MCE). RNA isolation, cDNA synthesis, and protein extraction TRIzol® reagent (cat. no.

(11) OTUD1 delays wound healing by regulating endothelial function and angiogenesis in diabetic miceJournal of advanced researchApril 27, 2025Zhang J, Li W, Liu Y, Zheng J, Liu G, He M, Zheng Z, Zhu M, Cho N, Liang G, et al.containing shRNA sequences targeting the CDS of a random gene was used (AAV2/BI30-CMV-shNC). MSAB (HY-120697, MedChemExpress, California, USA), a β-catenin inhibitor, was also employed. Db/db and db/m mice were

(12) Suppression of NLRP3 inflammasome by a small molecule targeting CK1α–β-catenin–NF-κB and CK1α–NRF2–mitochondrial OXPHOS pathways during mycobacterial infectionFrontiers in ImmunologyFebruary 28, 2025Qing Guan, Huan Xiong, Xiangyu Song, Sheng Liu, Yuanjun Guang, Qi Nie, Yan Xie, Xiao-Lian ZhangUSA) and/or D4476 (CK1α inhibitor, MCE, HY-10324, MedChemExpress, USA)/MSAB (β-catenin inhibitor, MCE, HY-120697)/PDTC (NF-κB inhibitor, MCE, HY-18738)/NRF2-IN-1 (NRF2 inhibitor, MCE, HY-101025) was added and cultured

(13) Epigenetic modification regulates the ligamentum flavum hypertrophy through miR-335-3p/SERPINE2/β-catenin signaling pathwayCell Mol Biol LettJanuary 3, 2025Yongzhao Zhao, Shuai Jiang, Longting Chen, Qian Xiang, Jialiang Lin, Weishi Lithe LF cells. To inhibit the β-catenin signaling pathway, the LF cells were treated with 5 μM MSAB (#HY-120697, MedChemExpress, USA) to promote the degradation of β-catenin protein. CRISPR/Cas9 system and miR-335-3p

(14) Epithelial differentiation of gingival mesenchymal stem cells enhances re-epithelialization for full-thickness cutaneous wound healingStem Cell Research & TherapyNovember 28, 2024Yongzheng Li, Lingling Dong, Yani Chen, Wenjin Cai, Guoli Yang, Ying Wanginsulin, hydrocortisone, epinephrine, thyroxine, transferrin, and selenium solution). MSAB (Cat. No. HY-120697, Wnt/β-catenin pathway inhibitor) was obtained from MedChemExpress (Monmouth Junction, NJ, USA). Human

(15) Concomitant targeting of FLT3 and SPHK1 exerts synergistic cytotoxicity in FLT3-ITD(+) acute myeloid leukemia by inhibiting β-catenin activity via the PP2A-GSK3β axisCell communication and signaling : CCSAugust 7, 2024Jiang L, Zhao Y, Liu F, Huang Y, Zhang Y, Yuan B, Cheng J, Yan P, Ni J, Jiang Y, et al.No. HY-13001), S1P (Cat. No. HY-108496), SKI-II (Cat. No. HY-13822, SPHK inhibitor), MSAB (Cat. No. HY-120697, β-catenin inhibitor), JTE-013 (Cat. No. HY-100675, S1P2 inhibitor), okadaic acid (Cat. No. HY-N6785,

(16) ISX-9 Promotes KGF Secretion From MSCs to Alleviate ALI Through NGFR-ERK-TAU-β-Catenin Signaling AxisStem Cells Translational MedicineMarch 15, 2024Yi Tian, Qinyi Deng, Xiaotong Yang, Chen Wang, Van Minh Le, Ri Ji, Xin Liang, Yun FengERK inhibitor: U0126-EtOH (IU0160, Solarbio). GSK-3β inhibitor: TWS 119 (Selleck, S1590). MSAB (MCE, HY-120697) is a β-catenin inhibitor. Animal Models Thirty-six male Sprague-Dawley (SD) rats that were 6-8 weeks

(17) Fbxw7 suppresses carcinogenesis and stemness in triple-negative breast cancer through CHD4 degradation and Wnt/β-catenin pathway inhibitionJournal of Translational MedicineJanuary 24, 2024Guodong Xiao, Weiping Lu, Jing Yuan, Zuyue Liu, Peili Wang, Huijie Fana humidified incubator with an atmosphere of 5% CO2 at 37 °C. Chemical reagents MSAB (10 μM, MCE, HY-120697) was used to inhibit Wnt/β-catenin signaling. LiCl (10 mM, MCE, HY-W094474) was used to activate Wnt/β-catenin

(18) A frog peptide provides new strategies for the intervention against skin wound healingCellular & Molecular Biology LettersJuly 28, 2023Chao Li, Zhe Fu, Tao Jin, Yixiang Liu, Naixin Liu, Saige Yin, Zhuo Wang, Yubing Huang, Yinglei Wang, Yingxuan Zhang, et al.MAPK signaling pathway inhibitor (1 μM, HY-N1966, MedChemExpress, USA), or β-catenin inhibitor (10 μM, HY-120697, MedChemExpress, USA). Cell proliferation The pro-proliferative effects of OA-RD17 (1 nM) on keratinocytes,

(19) Treatment of Radiation Bone Injury with Transplanted hUCB-MSCs via Wnt/Î²-CateninStem Cells InternationalNovember 28, 2021Yufeng Zhang, Huaxin Deng, Zhiqiang Yang, Zhe Chen, Sheng Zhang, Yufan Zhu, Min Yang, Houcheng Zhong, Fuling Zhou, Yuanlong Xie, et al.cocultivation for 48 h, it was used for subsequent experiments. For drug treatment, 10 μM MSAB (MCE, Cat# HY-120697) was used to inhibit Wnt/β-catenin signaling [18]. 2.3. RT-PCR Total RNA was extracted by using the

(20) Direct Targeting of β-Catenin by a Small Molecule Stimulates Proteasomal Degradation and Suppresses Oncogenic Wnt/β-Catenin SignalingCell reportsJune 28, 2016Hwang SY, Deng X, Byun S, Lee C, Lee SJ, Suh H, Zhang J, Kang Q, Zhang T, Westover KD, et al.

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MSAB from MedChemExpress

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