Parthenolide from MedChemExpress

Product Specs
ItemParthenolide
CompanyMedChemExpress
Price $66.00Supplier Page View Company Product Page
Catalog NumberHY-N0141
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.91%
TypeChemical
Molecular Weight248.32
FormulaC₁₅H₂₀O₃
Research AreaCancer

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(1) Parthenolide Attenuates Skeletal Muscle Atrophy Through Regulation of Protein Homeostasis and Inhibition of InflammationFASEB JMarch 31, 2026Yu Bai, Weiqing Li, Yahong Lu, Hehuan Lai, Lin Ye, Kechi Li, Chendi Wang, Yi Ding, Wenhao Li, Yitao Chen, et al.evaluate the protective effects of parthenolide. 2 Experimental Methods 2.1 Reagents Parthenolide (HY‐N0141) was obtained from MedChemExpress (MedChemExpress, USA). TNF‐α (CF09) was purchased from Novoprotein

(2) Parthenolide attenuated the endometriosis-like lesions by activating autophagy and suppressing NLRP3 inflammasome activityIran J Basic Med SciJanuary 1, 2026Luhongyuan Jin, Tingting Fu, Chi Chi, Jiayi Zhou, Jun Lin, Wenjie Houinflammasome assembly and activation. To investigate the regulatory effects of PTL (MedChemExpress, Cat. No.: HY-N0141, Purity 99.91%) on NLRP3 inflammasome activation and autophagy, cells primed with LPS (1 μg/ml) and

(3) Parthenolide Restores Testosterone Biosynthesis After Nanoplastic Exposure by Blocking ROS-Driven NF-κB Nuclear TranslocationAntioxidants (Basel)October 31, 2025Peng Zhao, Hao Yan, Runchang Wang, Jie Zhao, Xiangqin Zheng, Dinggang Li, Xitong Guo, Fengming Ji, Chunlan Long, Lianju Shen, et al.0.1% (v/v) in any treatment, and an equivalent vehicle control was included. PTL (Parthenolide; MCE, HY-N0141, USA) was dissolved in DMSO to prepare a stock solution at a concentration of 10 μM [29]. The stock

(4) Identification of Phialomustin-B (PHL-B) as a Novel Natural TRPA1 Channel InhibitorACS OmegaSeptember 2, 2025Priyanka Yadav, Ashutosh Sharma, Aditya Singh, Mansi Sharma, Appu Kumar Singh, Asif Ali, Aravind Singh KshatriNo. HY-N6018; Compound 25, Cat. No. HY-N6607; Compound 26, Cat. No. HY-113303; Compound 27, Cat. No. HY-N0141). The activators and inhibitors were also purchased from MedChemExpress (HC-067047, Cat. No. HY-100208;

(5) Signal-induced NLRP3 phase separation initiates inflammasome activationCell researchJune 1, 2025Zou G, Tang Y, Yang J, Fu S, Li Y, Ren X, Zhou N, Zhao W, Gao J, Ruan Z, et al.(HY-A0210), Z-VAD-FMK (HY-16658B), CL097 (HY-128799), MNS (HY-78263), Bay11-7082 (HY-13453), Parthenolide (HY-N0141), CY-09 (HY-103666) and Imiquimod (HY-B0180A) were obtained from MCE. 2-Bromohexadecanoic acid (21604-1

(6) Parthenolide improves sepsis-induced coagulopathy by inhibiting mitochondrial-mediated apoptosis in vascular endothelial cells through BRD4/BCL-xL pathwayJ Transl MedJanuary 17, 2025Jun Zhang, Xing Zhu, Yong Li, Yinyu Wu, Yunxia Du, Hai Yang, Zhengchao Liu, Haoyu Pei, Rui Li, Huan Luo, et al.and Ethics Committee of the Army Medical University (Approval No. AMUWEC20237118). Reagents PTL (HY-N0141) and B-cell lymphoma-extra large (BCL-xL) inhibitor A-1331852 (HY-19741) were purchased from MedChemExpress

(7) Gut microbiota dysbiosis promotes the development of epithelial ovarian cancer via regulating Hedgehog signaling pathwayGut microbesJanuary 1, 2023Hu X, Xu X, Zeng X, Jin R, Wang S, Jiang H, Tang Y, Chen G, Wei J, Chen T, et al.modeling and were treated as follows: (1) M group: EOC model; (2) P group: parthenolide (PTL; Cat# HY-N0141, MedChemExpress (MCE), USA) (10 mg/kg) were intraperitoneally injected (i.p.) three times a week, n

(8) A positive feedback loop between LINC01605 and NF-κB pathway promotes tumor growth in nasopharyngeal carcinomaRNA BiologyDecember 31, 2022Weiguo Zhao, Ling Xin, Lei Tang, Yunjing Li, Xueqin Li, Ruifeng LiuSigma-Aldrich), actinomycin D (4 μg/Ml; SBR00013, Sigma-Aldrich) and p65 inhibitor (parthenolide; PT; 5 μmol/L; HY-N0141, MedChemExpress, New Jersey, USA), were purchased. Quantitative real-time polymerase chain reaction

(9) Drug Repurposing to Identify a Synergistic High-Order Drug Combination to Treat Sunitinib-Resistant Renal Cell CarcinomaCancersAugust 6, 2021Rausch M, Rutz A, Allard PM, Delucinge-Vivier C, Docquier M, Dormond O, Dyson PJ, Wolfender JL, Nowak-Sliwinska P.disulfiram (HY-B0240), famotidine (HY-B0377), ivermectin (HY-15310), metformin (HY-17471A), parthenolide (HY-N0141) and verapamil (HY-A0064) were purchased through MedChemExpress (Monmouth Junction, NJ, USA). Erlotinib-HCl

(10) Parthenolide inhibits the growth of non-small cell lung cancer by targeting epidermal growth factor receptorCancer Cell InternationalDecember 1, 2020Xiaoling Li, Riming Huang, Mingyue Li, Zheng Zhu, Zhiyan Chen, Liao Cui, Hui Luo, Lianxiang LuoNSCLC. Materials and methods Reagents and antibodies Parthenolide was purchased from MedChemExpress (cat# HY-N0141) and dissolved in DMSO. The Annexin V-FITC/PI staining kit was was purchased from Thermofisher (cat#88-8005-72).

(11) Histone deacetylase 4 promotes cholestatic liver injury in the absence of prohibitin-1Hepatology (Baltimore, Md.)October 1, 2015Barbier-Torres L, Beraza N, Fernández-Tussy P, Lopitz-Otsoa F, Fernández-Ramos D, Zubiete-Franco I, Varela-Rey M, Delgado TC, Gutiérrez V, Anguita J, et al.

(12) NF-κB-dependent and -independent epigenetic modulation using the novel anti-cancer agent DMAPTCell death & diseaseJanuary 22, 2015Nakshatri H, Appaiah HN, Anjanappa M, Gilley D, Tanaka H, Badve S, Crooks PA, Mathews W, Sweeney C, Bhat-Nakshatri P.

(13) Parthenolide induces apoptosis via TNFRSF10B and PMAIP1 pathways in human lung cancer cellsJournal of experimental & clinical cancer research : CRJanuary 6, 2014Zhao X, Liu X, Su L.

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Parthenolide from MedChemExpress

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Parthenolide from MedChemExpress

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