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Protein Biochemistry
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Paprotrain
Paprotrain from MedChemExpress
Be the first to write a review!
Citations:
(6)
Supplier Page
Supplier Page from
MedChemExpress for
Paprotrain
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Description
Paprotrain is a cell-permeable inhibitor of the
kinesin MKLP-2
, inhibits the ATPase activity of MKLP-2 with an
IC
50
of 1.35 µM and a
K
i
of 3.36 µM and shows a moderate inhibition activity on
DYRK1A
with an
IC
50
of 5.5 µM
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Paprotrain
Company
MedChemExpress
Price
$55.00
Supplier Page
View Company Product Page
Catalog Number
HY-101298
Research Area
Neurological Disease
Formula
C₁₆H₁₁N₃
Molecular Weight
245.28
Type
Chemical
Purity
99.87%
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Quantity
10 mM * 1 mL
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (6)
(1)
The mechanoresponsive chromosomal passenger complex sustains furrow ingression under confinement
Journal of Molecular Cell Biology
November 11, 2025
Chenxin Wang, Jingjing Ding, Chao Wang, Maiyong Zhang, Junjie Wu, Bowen Chen, Hui Yang, Ting Gang Chew
Aurora B
inhibitor
: AZD1152-HQPA (
Selleckchem
,
S1147
); MKLP2
inhibitor
:
Paprotrain
(
MedChemExpress
,
HY-101298
); and MLCK
inhibitor
: ML-7 (MedChemExpress, 110448-33-4). These chemicals were dissolved in DMSO. Treatment
(2)
An acentrosomal aster with atypical microtubule polarity recruits cytokinesis signals to its center in Xenopus egg extracts
Journal of Cell Science
September 15, 2025
Ling Jin, Muchen Liu, Xianrui Cheng
S-trityl-L-cysteine (
L14384.03
,
Thermo Fisher
) was added to extracts to a final concentration of 100 µM.
Paprotrain
(
HY-101298
,
MedChemExpress
) was added to extracts at various concentrations as indicated, including 50 µM and 100
(3)
Further investigation of Paprotrain: Towards the conception of selective and multi-targeted CNS kinase inhibitors
European journal of medicinal chemistry
November 29, 2016
Labrière C, Lozach O, Blairvacq M, Meijer L, Guillou C.
(4)
KIF20A regulates porcine oocyte maturation and early embryo development
PloS one
January 1, 2014
Zhang Y, Liu J, Peng X, Zhu CC, Han J, Luo J, Rui R.
(5)
MKlp2 inhibitor paprotrain affects polar body extrusion during mouse oocyte maturation
Reproductive biology and endocrinology : RB&E
December 21, 2013
Liu J, Wang QC, Cui XS, Wang ZB, Kim NH, Sun SC.
(6)
Relocation of Aurora B and survivin from centromeres to the central spindle impaired by a kinesin-specific MKLP-2 inhibitor
Angewandte Chemie (International ed. in English)
October 25, 2010
Tcherniuk S, Skoufias DA, Labriere C, Rath O, Gueritte F, Guillou C, Kozielski F.
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Paprotrain from MedChemExpress
Supplier Page
View Company Product Page
$55.00
Product Specs
Company Info
Citations
Reviews
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