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Protein Biochemistry
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CVT-313
CVT-313 from MedChemExpress
Be the first to write a review!
Citations:
(6)
Supplier Page
Supplier Page from
MedChemExpress for
CVT-313
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Description
CVT-313 (Cdk2 Inhibitor III) is a potent, selective, reversible, and ATP-competitive inhibitor of
CDK2
with
IC
50
of 0.5 µM. CVT-313 inhibits CDC5L phosphorylation
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
CVT-313
Company
MedChemExpress
Price
$103.00
Supplier Page
View Company Product Page
Catalog Number
HY-15339
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.90%
Type
Chemical
Molecular Weight
400.47
Formula
C₂₀H₂₈N₆O₃
Research Area
Cancer
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (6)
(1)
CDC5L binds to ELAVL1 to inhibit pyroptosis in hepatocellular carcinoma through the Caspase 3/GSDME signaling pathway
International Journal of Molecular Medicine
September 12, 2025
Shuai Liang, Zhongcheng Zhu, Yangshuo Tang, Shuhua Zhou, Moyan Xiao, Xuejun Gong, Ke Ye
(
GSDME
-specific siRNA#2) groups. SK-HEP-1 and MHCC-97H cells were treated with 1 μM
CDC5L
inhibitor
CVT-313
(
HY-15339
;
MedChemExpress
) for 48 h (27) and divided into the following groups: Control,
CVT-313
,
CVT-313
+ si-NC
(2)
CDK9 Inhibition by Dinaciclib Is a Therapeutic Vulnerability in Epithelioid Hemangioendothelioma
Clinical Cancer Research
September 13, 2024
Ajaybabu V. Pobbati, Ashley Burtscher, Nandini Rajaram Rajaram Siva, Andrea Hallett, Todd Romigh, Kepeng Che, Bin Zhao, Jesse A. Coker, Nancy Wang, Shaun R. Stauffer,
et al.
triptonide (Cat #
HY-32736
), palbociclib (Cat #
HY-50767
),
RO-3306
(Cat #
HY-12529
),
CVT-313
(Cat #
HY-15339
), roscovitine (Cat #
HY-30237
),
AZD4573
(Cat #
HY-112088
) used in this study were purchased from
MedChemExpress
.
(3)
CDK9 inhibition by dinaciclib is a therapeutic vulnerability in epithelioid hemangioendothelioma
Clin Cancer Res
September 13, 2024
Ajaybabu V. Pobbati, Ashley Burtscher, Nandini Rajaram Siva, Andrea Hallett, Todd Romigh, Kepeng Che, Bin Zhao, Jesse A. Coker, Nancy Wang, Shaun R. Stauffer,
et al.
triptonide (Cat #
HY-32736
), palbociclib (Cat #
HY-50767
),
RO-3306
(Cat #
HY-12529
),
CVT-313
(Cat #
HY-15339
), roscovitine (Cat #
HY-30237
),
AZD4573
(Cat #
HY-112088
) used in this study were purchased from
MedChemExpress
.
(4)
Cell cycle-dependent phosphorylation of human CDC5 regulates RNA processing
Cell cycle (Georgetown, Tex.)
June 15, 2008
Gräub R, Lancero H, Pedersen A, Chu M, Padmanabhan K, Xu XQ, Spitz P, Chalkley R, Burlingame AL, Stokoe D,
et al
.
(5)
CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation
The Journal of biological chemistry
November 14, 1997
Brooks EE, Gray NS, Joly A, Kerwar SS, Lum R, Mackman RL, Norman TC, Rosete J, Rowe M, Schow SR,
et al
.
(6)
Radiation exposure to nursing personnel from patients receiving diagnostic radionuclides
Heart & lung : the journal of critical care
May 1, 1982
Burks J, Griffith P, McCormick K, Miller R.
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CVT-313 from MedChemExpress
Supplier Page
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$103.00
Product Specs
Company Info
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