RO5166017 from MedChemExpress | Biocompare.com

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RO5166017

Description

RO5166017 is an orally active and species-crosses TAAR1 agonist, with K_i values of 1.9 nM, 2.7 nM, 31 nM and 24 nM for mouse, rat, human and cynomolgus monkey, respectively

Product Specs
ItemRO5166017
CompanyMedChemExpress
Price $80.00Supplier Page View Company Product Page
Catalog NumberHY-12699
Quantity5 mg
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.37%
TypeChemical
Molecular Weight219.28
FormulaC₁₂H₁₇N₃O
Research AreaMetabolic Disease

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(1) Trace amine-associated receptor 1 agonists RO5263397 and RO5166017 attenuate quinpirole-induced yawning but not hypothermia in ratsBehavioural pharmacologyOctober 1, 2017Siemian JN, Zhang Y, Li JX.

(2) Necrophilous Staphylininae (Coleoptera: Staphylinidae) as indicators of season of death and corpse relocationForensic Sci IntSeptember 1, 2014Mądra A, Konwerski S, Matuszewski S.

(3) TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activityProceedings of the National Academy of Sciences of the United States of AmericaMay 17, 2011Revel FG, Moreau JL, Gainetdinov RR, Bradaia A, Sotnikova TD, Mory R, Durkin S, Zbinden KG, Norcross R, Meyer CA, et al.

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