P7C3 from MedChemExpress

Product Specs
ItemP7C3
CompanyMedChemExpress
Price $61.00Supplier Page View Company Product Page
Catalog NumberHY-15976
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.66%
TypeChemical
Molecular Weight474.19
FormulaC₂₁H₁₈Br₂N₂O
Research AreaNeurological Disease

Add to Compare List

MedChemExpress

1 Deer Park Drive, Suite F

MONMOUTH JUNCTION, NJ 08852

United States

Phone: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910

Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com

Company Profile

Website: medchemexpress.com

(1) Topical NAMPT activation restores mitophagic flux to rescue diabetic keratopathy via the NAD⁺/PINK1 pathwayCell Communication and SignalingMarch 9, 2026Qian Guo, Guannan Huang, Wanting Li, Yunjing Ma, Haini Liu, Zihao Liu, Limin Zhu, Lechong Ma, Qingjun Zhou, Shaozhen ZhaoGenePha-rma), an FK866 inhibitor (10 nM, 48 h; HY-50876, MedChemExpress), and a P7C3 agonist (10 µM, 48 h; HY-15976, MedChemExpress); Modulation of PINK1 expression via siRNA (50 nM, 48 h; sense: 5′-GAAGCCAUCUUGAACACAA-3′/antisense:

(2) Oxidative stress induces cell death partially by decreasing both mRNA and protein levels of nicotinamide phosphoribosyltransferase in differentiated PC12 cellsPeerJMay 14, 2021Cuiyan Zhou, Weihai YingLouis, MO, USA) was the supplier of H2O2 (323,381) and Nicotinamide (72,340). FK866 (HY-50876) and P7C3 (HY-15976) were purchased from MedChemExpress (Monmouth Junction, NJ, USA). Nampt siRNAs and control siRNAs were

(3) The Neurogenic Compound P7C3 Regulates the Aerobic Glycolysis by Targeting Phosphoglycerate Kinase 1 in GliomaFrontiers in oncologyJanuary 1, 2021Chen W, Jia W, Wu C, Chen L, Sun K, Wang J, Ding B, Liu N, Xu R.Methods Chemicals, Reagents, and Antibodies P7C3 (C21H18Br2N2O) was purchased from MedChemExpress (HY-15976, Monmouth Junction, NJ, USA). For in vitro experiments, P7C3 was dissolved in dimethyl sulfoxide (DMSO)

(4) Neurotherapeutic capacity of P7C3 agents for the treatment of Traumatic Brain InjuryNeuropharmacologyFebruary 1, 2019Blaya MO, Wasserman JM, Pieper AA, Sick TJ, Bramlett HM, Dietrich WD.

(5) P7C3 Inhibits LPS-Induced Microglial Activation to Protect Dopaminergic Neurons Against Inflammatory Factor-Induced Cell Death in vitro and in vivoFrontiers in cellular neuroscienceJanuary 1, 2018Gu C, Hu Q, Wu J, Mu C, Ren H, Liu CF, Wang G.

(6) P7C3 and an unbiased approach to drug discovery for neurodegenerative diseasesChemical Society reviewsOctober 7, 2014Pieper AA, McKnight SL, Ready JM.

(7) Discovery of a proneurogenic, neuroprotective chemicalCellJuly 9, 2010Pieper AA, Xie S, Capota E, Estill SJ, Zhong J, Long JM, Becker GL, Huntington P, Goldman SE, Shen CH, et al.

(8) Regulation of proopiomelanocortin gene expression in pituitaryEndocrine reviewsFebruary 1, 1988Lundblad JR, Roberts JL.

(9) A sensory and motor neuropathy caused by a genetic variant of NAMPTScience advancesJanuary 1, 0001"Zhang Z, Pilch J, Lundt S, Zhang N, Chang Y, Singer T, Śladowski D, Hu XL, Zheng L, Ge WP, et al."Sigma-Aldrich). For studying the effect of P7C3 and FK866 on thermal stability, 20 μM P7C3 (catalog no. HY-15976, MedChemExpress, NJ, USA) or 1 μM FK866 (catalog no. NIMH F-901) were included in the mixture. Temperature

(10) A novel multifunctional radioprotective strategy using P7C3 as a countermeasure against ionizing radiation-induced bone lossBone researchJanuary 1, 0001"Wei F, Tuong ZK, Omer M, Ngo C, Asiatico J, Kinzel M, Pugazhendhi AS, Khaled AR, Ghosh R, Coathup M."1% (v/v) penicillin/streptomycin in a humidified incubator containing 5% CO2 at 37 °C. P7C3 (500 mg, HY-15976) was purchased from MCE (MedChemExpress, USA). For the in vitro analyses, P7C3 was dissolved in dimethyl

Be the First to Write a Review!

Description

MedChemExpress

Citations (10)

Reviews

P7C3 from MedChemExpress

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map