DMAPT from MedChemExpress

Product Specs
ItemDMAPT
CompanyMedChemExpress
Price $66.00Supplier Page View Company Product Page
Catalog NumberHY-16172
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity98.0%
TypeChemical
Molecular Weight293.4
FormulaC₁₇H₂₇NO₃
Research AreaCancer

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(1) NF-κB inhibition attenuates sympathetic hyperreflexia and concomitant development of autonomic dysreflexia and immune dysfunction after spinal cord injuryCommun BiolMay 22, 2025Micaela L. O'Reilly, Mariah J. Wulf, Theresa M. Connors, Ying Jin, Frank Bearoff, Nan Hai, Julien Bouyer, Sandhya Kortagere, Yinghui Zhong, John R. Bethea, et al.simultaneously treated with DMAPT (1 μM, 10 μM, 100 μM, or 1000 μM in sterile DMSO; MedChemExpress, Cat. #HY-16172); Sigma, P0667) and lipopolysaccharide (LPS; 200 pg/mL; Sigma, #L4391). Control groups included untreated

(2) Chronic low dose ethanol induces an aggressive metastatic phenotype in TRAMP mice, which is counteracted by parthenolideClinical & experimental metastasisOctober 1, 2018Morel KL, Ormsby RJ, Solly EL, Tran LNK, Sweeney CJ, Klebe S, Cordes N, Sykes PJ.

(3) DMAPT inhibits NF-κB activity and increases sensitivity of prostate cancer cells to X-rays in vitro and in tumor xenografts in vivoFree radical biology & medicineNovember 1, 2017Mendonca MS, Turchan WT, Alpuche ME, Watson CN, Estabrook NC, Chin-Sinex H, Shapiro JB, Imasuen-Williams IE, Rangel G, Gilley DP, et al.

(4) Aminoparthenolides as novel anti-leukemic agents: Discovery of the NF-kappaB inhibitor, DMAPT (LC-1)Bioorganic & medicinal chemistry lettersAugust 1, 2009Neelakantan S, Nasim S, Guzman ML, Jordan CT, Crooks PA.

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