BPTES from MedChemExpress

Product Specs
ItemBPTES
CompanyMedChemExpress
Price $104.00Supplier Page View Company Product Page
Catalog NumberHY-12683
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity98.75%
TypeChemical
Molecular Weight524.68
FormulaC₂₄H₂₄N₆O₂S₃
Research AreaCancer

Add to Compare List

MedChemExpress

1 Deer Park Drive, Suite F

MONMOUTH JUNCTION, NJ 08852

United States

Phone: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910

Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com

Company Profile

Website: medchemexpress.com

(1) USP7 facilitates brain tumor survival upon glucose deprivation by regulating phosphofructokinase muscle-type nuclear translocation in micePLoS BiolMarch 12, 2026Siyang Wu, Ruixiu Cao, Xiaolan Huang, Qiongni Feng, Yajuan Zhang, Hong Gao, Bangbao Tao, Ji Liang, Weiwei YangChina). The PFK2 inhibitor-3PO (HY-19824), USP7 inhibitor-P22077 (HY-13865), glutaminase inhibitor BPTES (HY-12683) and FAO inhibitor Etomoxir (HY-50202) were purchased from MCE (MedChemExpress, China). The inhibitor

(2) Ageing promotes metastasis via activation of the integrated stress responseNatureMarch 11, 2026Angana A. H. Patel, Jozefina J. Dzanan, Kevin X. Ali, Ella A. Eklund, Samantha W. Alvarez, Dorota Raj, Martin Dankis, Ilayda Altinönder, Maria Schwarz, Kristell Le Gal, et al.ISRIB (HY-12495, MedChemExpress), bis-2-(5-phenylacetamido-1,3,4-thiadiazol-2-yl) ethyl sulfide (BPTES, HY-12683, MedChemExpress), V-9302 (HY-112683, MedChemExpress), ERG240 (HY-W193545A, MedChemExpress), branched-chain

(3) Single‐Mitochondrion ATP Profiling Directs Discovery of Targetable OXPHOS Dependency in CancersAdvanced ScienceFebruary 13, 2026Xu Xiao, Cheng Lu, Hao Chen, Jing Zhou, Yunyun Hu, Haonan Di, Guoqiang Su, Xiaomei YanHY‐16589), bedaquiline (BDQ, HY‐14881), rotenone (HY‐B1756), metformin (HY‐17471), VLX600 (HY‐12406), BPTES (HY‐12683), C‐968 (HY‐12682), CB‐839 (HY‐11248), and CPI‐613 (HY‐15453) were acquired from MedChemExpress. 5’‐Nucleotides

(4) Microbiota-induced EI24 improves homeostasis but impedes function of alveolar macrophages via metabolic regulationNature CommunicationsJanuary 31, 2026Yuanyuan Huang, Miya Su, Yuwei Zhang, Jun Pan, Yu Wang, Dongsheng Chen, Xuran Chen, Chenxi Tian, Huimin Zhang, Qiuying Sun, et al.HY-13966), Oligomycin (50 nM, MCE, HY-N6782), Mito-TEMPO (10 μM, MCE, HY-112879), and BPTES (10 μM, MCE, HY-12683) were added to sorted AMs. Antibodies and flow cytometry The fluorochrome-labeled or unlabeled antibodies

(5) Active LXR signaling, coupled with elevated mitochondrial and glycolytic metabolism contributes to GM-CSF–induced trained immunityFrontiers in ImmunologyJanuary 7, 2026Yuanyuan Liu, Arslan Hamid, Hannah Hardege, Qian Zhang, Helena Körner, Merle Leffers, Noelia A. Gonzalez, Gerhard Liebisch, Marcus Hoering, Hannes Findeisen, et al.(CPT-1a inhibitor, Medchemexpress, #HY-50202), 40 μM BPTES (Glutaminase inhibitor, Medchemexpress, HY-12683) or vehicle for 24 h in RPMI supplemented with 10% fetal bovine serum, 1 mM sodium pyruvate solution,

(6) Gut-to-brain signaling restricts dietary protein intake during recovery from catabolic statesCellDecember 24, 2025Nikolai P. Jaschke, Joseph R. Luchsinger, Zuojia Chen, Vera C. Wulfmeyer, Xavier de la Rosa, Oliver Hahn, Cuiling Zhang, Nathaniel D. Bachtel, Jaime L. Cullen, Tilman D. Rachner, et al.,Alomone Labs,Cat#R-400 fenclonine,Medchemexpress,Cat#HY-B1368 ally isothiocyanate (AITC),Sigma-aldrich,Cat# 377430 BPTES,Medchemexpress,Cat# HY-12683 Intesticult™ Organoid Growth Medium (Mouse),Stemcell Technologies,Cat# 06005 Corning™ Matrigel™ Gfr

(7) Hyperinflammation by Human Macrophages Induced by SARS-CoV-2 Anti-Spike IgG Is Dependent on Glucose and Fatty Acid MetabolismEur J ImmunolDecember 19, 2025Chiara E. Geyer, Luís Almeida, Lynn Mes, Frank Otto, W. Ashwin Mak, Graham A. Heieis, Jennifer Veth, Steven W. de Taeye, Tom G. Caniels, Tom P. L. Bijl, et al.Zombie NIR Fixable Viability Kit,Biolegend,Cat# 423106 2‐DG,MedChemExpress.com,Cat# HY‐13966 BPTES,MedChemExpress.com,Cat# HY‐12683 C75,MedChemExpress.com,Cat# HY‐12364 Etomoxir,MedChemExpress.com,Cat# HY‐50202 6‐AN,MedChemExpress.com,Cat#

(8) Glutaminase‐1 Mediated Glutaminolysis to Glutathione Synthesis Maintains Redox Homeostasis and Modulates Ferroptosis Sensitivity in Cancer CellsCell ProliferationNovember 1, 2025Changsen Bai, Jialei Hua, Donghua Meng, Yue Xu, Benfu Zhong, Miao Liu, Zhaosong Wang, Wei Zhou, Liming Liu, Hailong Wang, et al.(PC),1957/11/4,Aladdin,L130331 Phosphatidylglycerol (PG),1957/10/3,Aladdin,L130372 BPTES,314045‐39‐1,MCE,HY‐12683 ML‐210,1360705‐96‐9,MCE,HY‐100003 ED‐71,104121‐92‐8,MCE,HY‐A0020 CCK‐8,N/A,TargetMol,C0005 Reagents

(9) Glutamine alleviates immunosuppression in polymicrobial sepsis by augmenting bacterial phagocytosis through sustaining the GFAT-DRP1 dependent mitochondrial calcium dynamicsClinical ScienceOctober 22, 2025Yuanfeng Zhu, Xiaoli Chen, Lin Xia, Shijun Fan, Qian Chen, Yan Wei, Yongling Lu, Xin Liu, Xi Peng5’-(thiobis(ethane-2, 1-diyl))bis(1, 3, 4-thiadiazole-5, 2-diyl))bis(2-phenylacetimidic acid) (BPTES, HY-12683), and CGP37157 (HY-15754) were purchased from MCE (Monmouth Junction, NJ, U.S.A.). L-Gln (49419), lipopolysaccharides

(10) Glutamine alleviates immunosuppression in polymicrobial sepsis by augmenting bacterial phagocytosis through sustaining the GFAT-DRP1 dependent mitochondrial calcium dynamicsClin Sci (Lond)October 22, 2025Yuanfeng Zhu, Xiaoli Chen, Lin Xia, Shijun Fan, Qian Chen, Yan Wei, Yongling Lu, Xin Liu, Xi Peng5’-(thiobis(ethane-2, 1-diyl))bis(1, 3, 4-thiadiazole-5, 2-diyl))bis(2-phenylacetimidic acid) (BPTES, HY-12683), and CGP37157 (HY-15754) were purchased from MCE (Monmouth Junction, NJ, U.S.A.). L-Gln (49419), lipopolysaccharides

(11) Hesperetin Protects from Palmitic-Acid-Induced Lipotoxicity through the Inhibition of Glutaminolysis, mTORC1 Signaling, and Limited ApoptosisJournal of Agricultural and Food ChemistrySeptember 3, 2025Wan Li, Zhengnan Cai, Florian Schindler, Martin Brenner, Christian Winter, Bianca Stiller, Petra Heffeter, Wolfram WeckwerthSanta Cruz Biotechnology (Heidelberg, Germany), and bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2yl)ethyl sulfide (BPTES) (HY-12683) and Rapamycin (RAP) (HY-10219) were purchased from MedChemExpress (Monmouth Junction, NJ, USA). All

(12) Chaperone-mediated autophagy directs a dual mechanism to balance premature senescence and senolysis to prevent intervertebral disc degenerationBone ResJune 12, 2025Zhangrong Cheng, Haiyang Gao, Pengzhi Shi, Anran Zhang, Xianglong Chen, Yuhang Chen, Weikang Gan, Kangcheng Zhao, Shuai Li, Cao Yang, et al.experiments. Drugs and cell processing AR7 (#HY-101106), Chloroquine/CQ (#HY-17589A), 3MA (#HY-19312), BPTES (#HY-12683), apoptosis inducer-10/AI-10 (#HY-146255), IL1B (#HY-P73149), All-trans Retinoic acid/ATRA (#HY-14649),

(13) TIGIT deficiency promotes autoreactive CD4(+) T-cell responses through a metabolic‒epigenetic mechanism in autoimmune myositisNature communicationsMay 15, 2025Lai Y, Wang S, Ren T, Shi J, Qian Y, Wang S, Zhou M, Watanabe R, Li M, Ruan X, et al.some experiments, UK5099 (Cat# HY-15475), MSDC-0206 (Cat# HY-108022), ETO (Cat# HY-50202), BPTES (Cat# HY-12683), PI-103 (Cat# HY-10115, all from MCE), C646 (Cat# S7152), or BEZ235 (Cat# S1009, both from Selleck)

(14) Dysregulation of muscle cholesterol transport in amyotrophic lateral sclerosisBrainMarch 6, 2025Delphine Sapaly, Flore Cheguillaume, Laure Weill, Zoé Clerc, Olivier Biondi, Sabrina Bendris, Céline Buon, Rasha Slika, Elsie Piller, Venkat Krishnan Sundaram, et al.inhibitor of carnitine palmitoyltransferase 1a (CPT1-A), and after injecting a mixture of 3 µM BPTES (HY-12683, MedChemExpress) a glutaminase inhibitor and 2 µM UK5099 (HY-15475, MedChemExpress), an inhibitor of

(15) Blimp-1 orchestrates macrophage polarization and metabolic homeostasis via purine biosynthesis in sepsisCell Death DisFebruary 6, 2025Wenjuan Peng, Qiushi Qin, Rui Li, Yujia Liu, Lan Li, Yue Zhang, Liuluan ZhuSigma-Aldrich, Germany) were used to induce 2-day polarization into M2 macrophages. A 10 mM GLS inhibitor BPTES (HY-12683, MCE, USA) was selected to inhibit the glutamine metabolic pathway, while 20 mM L-Glutamine (HY-N0390,

(16) MANF facilitates breast cancer cell survival under glucose-starvation conditions via PRKN-mediated mitophagy regulationAutophagyJanuary 2, 2025Zhenchong Xiong, Lin Yang, Chao Zhang, Weiling Huang, Wenjing Zhong, Jiarong Yi, Jikun Feng, Xiazi Zouxu, Libing Song, Xi Wangwere used at a concentration of 10 µM and 1 µM, respectively. Etomoxir (MCE, HY-50202) and BPTES (MCE, HY-12683) were used at concentrations of 40 and 10 µM. MG132 (Sigma, M7449) was used at 10 µM, whereas CHX (Sigma

(17) Formoterol Reduces the Pro‐Inflammatory Phenotype by Enhancing the Activity of Glutaminase in Monocyte‐Derived Macrophages in the CVB3‐Induced Viral MyocarditisImmunity, Inflammation and DiseaseNovember 27, 2024Quan‐liang Li, Hua‐bao Xie, Ying‐xin Guo, Juan‐fen Li, Jing Qian, Wei‐Feng Wustimulation, cells were pretreated with either 10− 6 M formoterol [31] or 10‐mM GLS inhibitor BPTES (HY‐12683, MCE, USA) [22] for in vitro intervention for 1 h, with 0.1% DMSO serving as the solvent control, as

(18) The critical role of glutamine and fatty acids in the metabolic reprogramming of anoikis-resistant melanoma cellsFrontiers in PharmacologyAugust 8, 2024S. Peppicelli, T. Kersikla, G. Menegazzi, E. Andreucci, J. Ruzzolini, C. Nediani, F. Bianchini, L. Calorinicomplex I inhibitor (557,368, Sigma-Aldrich, Milan, Italy); BPTES, a selective glutaminase inhibitor (HY-12683, MedchemExpress), Denifanstat, a Fatty Acid Synthase (FASN) inhibitor (HY-112829, MedchemExpress); Etomoxir,

(19) Elevated PINK1/Parkin-Dependent Mitophagy and Boosted Mitochondrial Function Mediate Protection of HepG2 Cells from Excess Palmitic Acid by HesperetinJournal of Agricultural and Food ChemistryJune 12, 2024Wan Li, Zhengnan Cai, Florian Schindler, Leila Afjehi-Sadat, Bianca Montsch, Petra Heffeter, Elke H. Heiss, Wolfram WeckwerthHY-B0579), JC-1 kits (HY-K0601), oligomycin (HY-N6782), rotenone (HY-B1756), FCCP (HY-50202), BPTES (HY-12683), etomoxir (HY-50202), UK5099 (HY-15475), and CCK-8 (HY-K0301) were obtained from MedChemExpress, New

(20) IGF2BP3 promotes glutamine metabolism of endometriosis by interacting with UCA1 to enhances the mRNA stability of GLS1Molecular MedicineMay 17, 2024Honglin Wang, Yingying Cao, Yanling Gou, Hao Wang, Zongwen Liang, Qiong Wu, Jiahuan Tan, Jinming Liu, Zhi Li, Jing Cui, et al.mouse models. In the experiment group, mice received intraperitoneal injections of 50 μg of BPTES (HY-12683, MCE, China) every 4 days starting from day 3, while the control group received PBS injections. The

Be the First to Write a Review!

Description

MedChemExpress

Citations (31)

Reviews

BPTES from MedChemExpress

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map