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Phosphoramide mustard cyclohexanamine
Phosphoramide mustard cyclohexanamine from MedChemExpress
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Citations:
(8)
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Phosphoramide mustard cyclohexanamine
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Description
Phosphoramide mustard cyclohexanamine is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA damage
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Phosphoramide mustard cyclohexanamine
Company
MedChemExpress
Price
$340.00
Supplier Page
View Company Product Page
Catalog Number
HY-137316A
Quantity
5 mg
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Type
Chemical
Molecular Weight
320.2
Formula
C₁₀H₂₄Cl₂N₃O₂P
Research Area
Cancer
Purity
98.0%
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (8)
(1)
Regulation of mitochondrial ROS by C15ORF48 in a basal cell subpopulation contributes to chemotherapy resistance in TNBC
Sci Adv
April 3, 2026
Yan Jiang, Noor M. Abdulkareem, Amanda L. Rinkenbaugh, Yuan Qi, Steven W. Wall, Xiaomei Zhang, Jiansu Shao, Sabrina Jeter-Jones, Shirong Cai, Faiza Baameur Hancock,
et al.
of A (doxorubicin hydrochloride; Sigma-Aldrich, D1515) or C (phosphoramide mustard;
MedChemExpress
,
HY-137316A
) alone, or with AC (200 nM doxorubicin plus 200 μM phosphoramide mustard). At 72 hours posttreatment,
(2)
Loss of FAT1 drives cyclophosphamide resistance in breast cancer via the Wnt/β-Catenin pathway
Int J Biol Sci
January 1, 2026
Lijing Zhong, Dongyan Cao, Chen Zheng, Liyi Zhang, Yuxuan Xu, Shasha Zhao, Xiao Liu, Guiying Wei, Gengming Niu, Heming Xu,
et al.
Palbociclib
(
MCE
,
HY-50767
) and
Phosphoramide mustard cyclohexanamine
(active metabolite of CTX;
MCE
,
HY-137316A
). For cell lines, 2×103 cells per well were seeded into a 96-well plate (Corning) and cultured for 24
(3)
Exosomes Derived From Human Mesenchymal Stem Cells Mitigate Follicular Interstitial Cell Ferroptosis via the miR-26a-5p/PTEN/GPX4 Axis in Rats with Chemotherapy-Induced Premature Ovarian Insufficiency
Int J Nanomedicine
August 22, 2025
Juntong Chen, Xingyu Huo, Maojiao Qian, Qian Xue, Yu He, Pengzhan Xu, Yueming Wang, Xiaoxuan Tang, Qianqian Luo, Hongchu Bao,
et al.
was purchased from Meilun Biotechnology (MB1315-1, Meilunbio, Dalian, China).
Phosphoramide mustard
(
HY-137316A
) was purchased from
MCE
Corporation. Antibodies against
PTEN
(#
10047-1-AP
),
Nrf2
(#
16396-1-AP
), GPX4
(4)
Exosomes Derived From Human Mesenchymal Stem Cells Mitigate Follicular Interstitial Cell Ferroptosis via the miR-26a-5p/PTEN/GPX4 Axis in Rats with Chemotherapy-Induced Premature Ovarian Insufficiency
Int J Nanomedicine
August 22, 2025
Juntong Chen, Xingyu Huo, Maojiao Qian, Qian Xue, Yu He, Pengzhan Xu, Yueming Wang, Xiaoxuan Tang, Qianqian Luo, Hongchu Bao,
et al.
was purchased from Meilun Biotechnology (MB1315-1, Meilunbio, Dalian, China).
Phosphoramide mustard
(
HY-137316A
) was purchased from
MCE
Corporation. Antibodies against
PTEN
(#
10047-1-AP
),
Nrf2
(#
16396-1-AP
), GPX4
(5)
hUMSCs restore ovarian function in POI mice by regulating GSK3β-mediated mitochondrial dynamic imbalances in theca cells
Scientific Reports
August 16, 2024
Yanlian Xiong, Yaru Si, Rengui Quan, Xingyu Huo, Juntong Chen, Jinyu Xu, Zhonglin Jiang, Feibo Xu, Ranran Liu, Qiang Fu
(MB1315-1, Meilunbio, Dalian, China). The GSK3β
inhibitor
SB26763 (
HY-12012
),
Phosphoramide mustard
(
HY-137316A
) was purchased from
MCE
corporation. The
DAPI
(C0065) and Dimethyl sulfoxide (DMSO) (D8371) were obtained
(6)
Phosphoramide mustard exposure induces DNA adduct formation and the DNA damage repair response in rat ovarian granulosa cells
Toxicology and applied pharmacology
February 1, 2015
Ganesan S, Keating AF.
(7)
Brain and plasma pharmacokinetics and anticancer activities of cyclophosphamide and phosphoramide mustard in the rat
Cancer chemotherapy and pharmacology
January 1, 1990
Genka S, Deutsch J, Stahle PL, Shetty UH, John V, Robinson C, Rapoport SI, Greig NH.
(8)
Stage-specific antigens on the surface membrane of sporozoites of malaria parasites
Nature
July 6, 1978
Nardin EH, Nussenzweig RS.
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Phosphoramide mustard cyclohexanamine from MedChemExpress
Supplier Page
View Company Product Page
$340.00
Product Specs
Company Info
Citations
Reviews
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