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Protein Biochemistry
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GSK 3 Inhibitor IX
GSK 3 Inhibitor IX from MedChemExpress
Be the first to write a review!
Citations:
(7)
Supplier Page
Supplier Page from
MedChemExpress for
GSK 3 Inhibitor IX
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Description
GSK 3 Inhibitor IX (6-Bromoindirubin-3'-oxime; BIO) is a potent, selective, reversible and ATP-competitive inhibitor of
GSK-3α/β
and
CDK1-cyclinB
complex with
IC
50
s of 5 nM/320 nM/80 nM for (GSK-3α/β)/CDK1/CDK5, respectively
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
GSK 3 Inhibitor IX
Company
MedChemExpress
Price
$116.00
Supplier Page
View Company Product Page
Catalog Number
HY-10580
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.73%
Formula
C16H10BrN3O2
Research Area
Cancer
Type
Chemical
Molecular Weight
356.17
Quantity
10 mM * 1 mL
Molecule Name
GSK 3 Inhibitor IX
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (7)
(1)
The FBXW7‐RPAP2 Axis Controls the Growth of Hepatocellular Carcinoma Cells and Determines the Fate of Liver Cell Differentiation
Advanced Science
February 11, 2025
Danrui Cui, Shengpeng Shao, Ruirui Qu, Xiaoyu Chen, Shanghong Jiang, Linchen Wang, Longyuan Gong, Tianqi Li, Danyi Zhai, Wenfeng Song,
et al.
MG132
(10 012 628,
Cayman
), PS‐341 (
HY‐10227
,
MCE
), CQ (
C6628
,
Sigma
), CHX (
C7698
,
Sigma
), GSK3i‐IX (
HY‐10580
,
MCE
), SB203580 (
HY‐10256
,
MCE
),
U0126
(
9903
,
Cell Signaling Technology
),
SP600125
(
HY‐12041
,
MCE
),
(2)
The cross talk of two family members of β-TrCP in the regulation of cell autophagy and growth
Cell death and differentiation
March 1, 2020
Cui D, Dai X, Shu J, Ma Y, Wei D, Xiong X, Zhao Y.
(P5499; Sigma),
AICAR
(
A9978
;
Sigma
),
LY294002
(
S1105
;
Selleck
),
BI-D1870
(
S2843
;
Selleck
), GSK3i-IX (
HY-10580
;
MCE
),
D4476
(
S7642
;
Selleck
), and
CX-4945
(
S2248
;
Selleck
). IB
and immunoprecipitation
(IP) For direct
(3)
6-Bromoindirubin-3'-oxime inhibits JAK/STAT3 signaling and induces apoptosis of human melanoma cells
Cancer research
June 1, 2011
Liu L, Nam S, Tian Y, Yang F, Wu J, Wang Y, Scuto A, Polychronopoulos P, Magiatis P, Skaltsounis L,
et al
.
(4)
The GSK-3 inhibitor BIO promotes proliferation in mammalian cardiomyocytes
Chemistry & biology
September 1, 2006
Tseng AS, Engel FB, Keating MT.
(5)
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
Nature medicine
January 1, 2004
Sato N, Meijer L, Skaltsounis L, Greengard P, Brivanlou AH.
(6)
GSK-3-selective inhibitors derived from Tyrian purple indirubins
Chemistry & biology
December 1, 2003
Meijer L, Skaltsounis AL, Magiatis P, Polychronopoulos P, Knockaert M, Leost M, Ryan XP, Vonica CA, Brivanlou A, Dajani R,
et al
.
(7)
Inhibiting prolactin: first they had to find it
JAMA
August 3, 1979
González ER.
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GSK 3 Inhibitor IX from MedChemExpress
Supplier Page
View Company Product Page
$116.00
Product Specs
Company Info
Citations
Reviews
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