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Ravoxertinib hydrochloride
Ravoxertinib hydrochloride from MedChemExpress
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Citations:
(2)
Supplier Page
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Ravoxertinib hydrochloride
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Description
Ravoxertinib hydrochloride (GDC-0994 hydrochloride) is an orally bioavailable inhibitor selective for
ERK
kinase activity with
IC
50
of 6.1 nM and 3.1 nM for
ERK1
and
ERK2
, respectively
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Ravoxertinib hydrochloride
Company
MedChemExpress
Price
$106.00
Supplier Page
View Company Product Page
Catalog Number
HY-15947A
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.44%
Type
Chemical
Molecular Weight
477.32
Formula
C₂₁H₁₉Cl₂FN₆O₂
Research Area
Cancer
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (2)
(1)
Ravoxertinib Improves Long-Term Neurologic Deficits after Experimental Subarachnoid Hemorrhage through Early Inhibition of Erk1/2
ACS Omega
June 6, 2023
Ming-feng Yang, Sheng-yao Sun, Hai-guang Lv, Wei-qi Wang, Han-xia Li, Jing-yi Sun, Zong-yong Zhang
a single i.c.v.
injection
(0.8 mm posterior, 1.2 mm lateral, and 3.8 mm depth) of RAH (5 μL, 50 μM;
HY-15947A
,
MedChemExpress
) or vehicle (5 μL, saline) with a 10 μL Hamilton syringe on a stereotaxic apparatus. 4.4
(2)
Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development
Journal of medicinal chemistry
June 23, 2016
Blake JF, Burkard M, Chan J, Chen H, Chou KJ, Diaz D, Dudley DA, Gaudino JJ, Gould SE, Grina J,
et al
.
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Ravoxertinib hydrochloride from MedChemExpress
Supplier Page
View Company Product Page
$106.00
Product Specs
Company Info
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Reviews
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