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Protein Biochemistry
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Splitomicin
Splitomicin from MedChemExpress
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Citations:
(4)
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Splitomicin
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Description
Splitomicin (Splitomycin) is a selective
Sir2p
inhibitor. Splitomicin inhibits NAD
+
-dependent HDAC activity of Sir2 protein. Splitomicin induces dose-dependent inhibition of HDAC in the yeast extract with an
IC
50
of 60 µM
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Splitomicin
Company
MedChemExpress
Price
$55.00
Supplier Page
View Company Product Page
Catalog Number
HY-100585
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
98.42%
Type
Chemical
Molecular Weight
198.22
Formula
C₁₃H₁₀O₂
Research Area
Cancer
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (4)
(1)
Sirt1 inhibition promotes in vivo arterial thrombosis and tissue factor expression in stimulated cells
Cardiovascular research
February 1, 2011
Breitenstein A, Stein S, Holy EW, Camici GG, Lohmann C, Akhmedov A, Spescha R, Elliott PJ, Westphal CH, Matter CM,
et al
.
(2)
Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells
Oncogene
January 12, 2006
Ota H, Tokunaga E, Chang K, Hikasa M, Iijima K, Eto M, Kozaki K, Akishita M, Ouchi Y, Kaneki M.
(3)
Identification of a small molecule inhibitor of Sir2p
Proceedings of the National Academy of Sciences of the United States of America
December 18, 2001
Bedalov A, Gatbonton T, Irvine WP, Gottschling DE, Simon JA.
(4)
Soil environment factors affecting organo-chlorinated pesticide persistence
Environmental quality and safety. Supplement
January 1, 1975
Guenzi WD, Beard WE.
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Splitomicin from MedChemExpress
Supplier Page
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$55.00
Product Specs
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