Dioscin from MedChemExpress

Product Specs
ItemDioscin
CompanyMedChemExpress
Price $84.00Supplier Page View Company Product Page
Catalog NumberHY-N0124
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.95%
TypeChemical
Molecular Weight869.04
FormulaC₄₅H₇₂O₁₆
Research AreaCardiovascular Disease; Cancer

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(1) Targeting the BMI1-Noxa axis by Dioscin induces apoptosis in oral squamous cell carcinoma cellsJournal of CancerJanuary 1, 2025Jinglin Fang, Ruirui Wang, Xiaoying Li, XiaoCong Wang, Lingling Gong, An Lou, Jie Lu, Xiaoyue Zhang, Qin Zhao, Xinfang Yu, et al.exert its anti-tumor activity. Materials and Methods Reagents and plasmid constructs Dioscin (#HY-N0124, purity>99%) and Z-VAD-FMK (#HY-16658) were purchased from MCE. Necrostatin-1 (#S8037) was purchased

(2) Dioscin inhibiting EGFR-mediated Survivin expression promotes apoptosis in oral squamous cell carcinoma cellsJournal of CancerJuly 9, 2023Ming Li, Qin Zhao, Jinzhuang Liao, Xiaocong Wang, Lulu Liu, Xiaoyue Zhang, Lijun Liu, Haidan Liu, Shusheng Zhangpreventing and treating OSCC. Materials and Methods Reagents and antibodies Dioscin (> 98% purity, #HY-N0124) was purchased from MedChemExpress (Monmouth Junction, NJ). Other chemical reagents, such as dimethylsulfoxide

(3) Dioscin Protects against Aβ1-42 Oligomers-Induced Neurotoxicity via the Function of SIRT3 and AutophagyChemical & pharmaceutical bulletinJanuary 1, 2020Zhang Z, Han K, Wang C, Sun C, Jia N.when they grew into the density of 80–90%. To optimize the concentration of dioscin (MedChemExpress, HY-N0124, China), cells were pretreated with 100, 200, 400, 800 or 1600 nmol/L dioscin for 1 h and then added

(4) Dioscin Promotes Prostate Cancer Cell Apoptosis and Inhibits Cell Invasion by Increasing SHP1 Phosphorylation and Suppressing the Subsequent MAPK Signaling PathwayFrontiers in pharmacologyJanuary 1, 2020He S, Yang J, Hong S, Huang H, Zhu Q, Ye L, Li T, Zhang X, Wei Y, Gao Y.special treatment (group A: L-C81); LNCaP-C81 cells treated with the optimal dioscin dose (Cat. No.: HY-N0124, Purity: 98.33%, MedChemExpress LLC, Monmouth Junction, NJ, USA) (group B: L-C81 + D); SHP1 knockdown

(5) Dioscin enhances osteoblastic cell differentiation and proliferation by inhibiting cell autophagy via the ASPP2/NF-κβ pathwayMolecular medicine reportsOctober 1, 2017Zhu C, Bao N, Chen S, Zhao J.humidified atmosphere of 5% CO2. Then, the cells (~2x105) were treated with dioscin (0.1, 0.5, 1, 5, 10 and 25 µg/ml; HY‑N0124; Medchemexpress, Monmouth Junction, NJ, USA) for 24, 48 and 72 h. CAPE (1 µM; S7414; Selleck Chemicals,

(6) Dioscin-induced apoptosis of human LNCaP prostate carcinoma cells through activation of caspase-3 and modulation of Bcl-2 protein familyJournal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen banFebruary 1, 2014Chen J, Li HM, Zhang XN, Xiong CM, Ruan JL.

(7) Dioscin inhibits osteoclast differentiation and bone resorption though down-regulating the Akt signaling cascadesBiochemical and biophysical research communicationsJanuary 10, 2014Qu X, Zhai Z, Liu X, Li H, Ouyang Z, Wu C, Liu G, Fan Q, Tang T, Qin A, et al.

(8) Dioscin prevents the mitochondrial apoptosis and attenuates oxidative stress in cardiac H9c2 cellsDrug researchJanuary 1, 2014Qin J, Kang Y, Xu Z, Zang C, Fang B, Liu X.

(9) [Clinical picture and type of myoclonus epilepsy with dominant heredity (author's transl)]Seishin shinkeigaku zasshi = Psychiatria et neurologia JaponicaJanuary 1, 1979Naito H, Kaji S.

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Dioscin from MedChemExpress

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Dioscin from MedChemExpress

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