Pan-RAS-IN-1 from MedChemExpress

Product Specs
ItemPan-RAS-IN-1
CompanyMedChemExpress
Price $284.00Supplier Page View Company Product Page
Catalog NumberHY-101295
Molecule NamePan-RAS-IN-1
Quantity10 mM * 1 mL
Molecular Weight717.65
TypeChemical
Research AreaCancer
FormulaC36H41Cl2F3N6O2
Purity99.16%
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting

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(1) ZFYVE28 mediates insulin resistance by promoting phosphorylated insulin receptor degradation via increasing late endosomes productionNature CommunicationsOctober 26, 2023Liang Yu, Mengchen Xu, Yupeng Yan, Shuchen Huang, Mengmeng Yuan, Bing Cui, Cheng Lv, Yu Zhang, Hongrui Wang, Xiaolei Jin, et al.reached 70–80%. Alternatively, cells were treated with GSK690693 (MCE, HY-10249), Pan-RAS-IN-1 (MCE, HY-101295), KRA-533 (MCE, HY-138188) and PD98059 (MCE, HY-12028) for the appropriate time at concentrations referred

(2) Patient-derived iPSC-cerebral organoid modeling of the 17q11.2 microdeletion syndrome establishes CRLF3 as a critical regulator of neurogenesisCell reportsJuly 6, 2021Wegscheid ML, Anastasaki C, Hartigan KA, Cobb OM, Papke JB, Traber JN, Morris SM, Gutmann DH.activity assays For small molecule treatments, 14DIV hCOs were incubated with 10 μM Pan-RAS-IN-1 (HY-101295, MedChemExpress) for 48 hours, and RAS activity (STA-440, Cell Biolabs) was determined on liquid nitrogen

(3) Targeting USP47 overcomes tyrosine kinase inhibitor resistance and eradicates leukemia stem/progenitor cells in chronic myelogenous leukemiaNature communicationsJanuary 4, 2021Lei H, Xu HZ, Shan HZ, Liu M, Lu Y, Fang ZX, Jin J, Jing B, Xiao XH, Gao SM, et al.(Houston, TX, USA). AZD6738 (T3338) was purchased from Target Molecule Corp. (Shanghai, CHN). Pan-RAS-IN-1 (HY-101295) was purchased from MedChemExpress LLC. (Monmouth Junction, NJ, USA). The Cell Cycle Detection Kit (340242)

(4) Multivalent Small-Molecule Pan-RAS InhibitorsCellFebruary 23, 2017Welsch ME, Kaplan A, Chambers JM, Stokes ME, Bos PH, Zask A, Zhang Y, Sanchez-Martin M, Badgley MA, Huang CS, et al.

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Pan-RAS-IN-1 from MedChemExpress

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Pan-RAS-IN-1 from MedChemExpress

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