AM095 from MedChemExpress

Product Specs
ItemAM095
CompanyMedChemExpress
Price $80.00Supplier Page View Company Product Page
Catalog NumberHY-16039
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.72%
TypeChemical
Molecular Weight478.47
FormulaC₂₇H₂₃N₂NaO₅
Research AreaInflammation/Immunology

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(1) The LPA-CDK5-tau pathway mediates neuronal injury in an in vitro model of ischemia-reperfusion insultBMC neurologyMay 2, 2022Wang Y, Zhang J, Huang L, Mo Y, Wang C, Li Y, Zhang Y, Zhang Z.were purchased from Beyotime. Cell count kit 8 (CCK-8, HY-K0301), LPA1 receptor antagonist (AM095, HY-16039) and LPA2 receptor antagonist (HY-18075) were purchased from MedChemExpress. Autotaxin inhibitor (PF8380)

(2) A SNP of bacterial blc disturbs gut lysophospholipid homeostasis and induces inflammation through epithelial barrier disruptionEBioMedicineFebruary 1, 2020Zou D, Pei J, Lan J, Sang H, Chen H, Yuan H, Wu D, Zhang Y, Wang Y, Wang D, et al.LPE (20 μM) was incubated in the presence or absence of protein inhibitors, including AM095 (MCE Cat# HY-16039), Ki16425 (MCE Cat# HY-13285), HA130 (MCE Cat# HY-19329), GLPG1690 (MCE Cat# HY-101772) and GF-109203X

(3) Lysophosphatidic Acid Induces Apoptosis of PC12 Cells Through LPA1 Receptor/LPA2 Receptor/MAPK Signaling PathwayFrontiers in molecular neuroscienceJanuary 1, 2020Zhang J, Li Y, Wang C, Wang Y, Zhang Y, Huang L, Zhang Z.purchased from Proteintech. Cell Counting Kit-8 (CCK-8, HY-K0301), LPA1 receptor antagonist (AM095, HY-16039; BMS986020, HY-100619), LPA2 receptor antagonist (HY-18075), ERK1/2 inhibitor (U0126, HY-12031), p38

(4) Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of sclerodermaArthritis and rheumatismMay 1, 2011Castelino FV, Seiders J, Bain G, Brooks SF, King CD, Swaney JS, Lorrain DS, Chun J, Luster AD, Tager AM.

(5) Pharmacokinetic and pharmacodynamic characterization of an oral lysophosphatidic acid type 1 receptor-selective antagonistThe Journal of pharmacology and experimental therapeuticsMarch 1, 2011Swaney JS, Chapman C, Correa LD, Stebbins KJ, Broadhead AR, Bain G, Santini AM, Darlington J, King CD, Baccei CS, et al.

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AM095 from MedChemExpress

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