Norepinephrine from MedChemExpress

Product Specs
ItemNorepinephrine
CompanyMedChemExpress
Price $50.00Supplier Page View Company Product Page
Catalog NumberHY-13715
Quantity100 mg
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.61%
TypeChemical
Molecular Weight169.18
FormulaC₈H₁₁NO₃
Research AreaEndocrinology; Cardiovascular Disease; Cancer

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(1) Mas‐Related G Protein‐Coupled Receptor Member D Sustains HypertensionMedComm (2020)April 1, 2026Kun Zhao, Dongxu Hua, Yukang Mao, Xiaoguang Wu, Min Gao, Shidong Song, Lei Chen, Xiangxiang Zheng, Peng Livasoconstrictive responses were elicited by cumulative concentrations of PGF2α (Sigma, CAS 4510‐16‐1) or NE (MCE, HY‐13715) over a concentration range of 10−9 to 10−4 M. Endothelium‐dependent and ‐independent vasorelaxation

(2) Sympathetic nerve aggravates autoimmune skin disease via NE-adrenergic receptor axis: Neuroimmune cross-talk insights from vitiligoSci AdvMarch 6, 2026Luling Huang, Pan Kang, Jiaxi Chen, Weiwei Sun, Hang Yin, Yuqi Yang, Sen Guo, Xiuli Yi, Jianru Chen, Shuli Li, et al.(L3000015, Invitrogen, USA) following the manufacturer’s protocol. Treating HaCaT cells with 5 μM NE (HY-13715, MedChemExpress, Monmouth Junction, NJ, USA) alone or in combination with 1 μM ICI (HY-13951, MedChemExpress,

(3) CARD9 Conveys Pancreatic Islet Sympathetic Nervous β2 Signals to Reshape Macrophage Creatine Metabolism in Type 1 DiabetesAdvanced ScienceJanuary 1, 2026Huimin Yuan, Senlin Li, Shuai Liu, Hong Zhou, Yue Xu, Wenhui Li, Mengxuan Wang, Mengheng Wang, Mengzhu Zheng, Wenxi Shi, et al.studies, cells were pre‐treated with FMT (100 nm) or BTX (10 µm) for 2 h and then treated with NE (100 nm; HY‐13715, MedChemExpress, USA) for 12 h.[ 39 , 40 , 41 ] The mouse CARD9 expression plasmids and shCard9

(4) Augmentation of bone formation by sympathectomy in rats as evaluated by [99mTc]Tc-MDPFront Endocrinol (Lausanne)July 2, 2025Zili Cai, Xiuting Lin, Yuehong Zhuang, Weibing Miao, Yun Xiesympathetic neurons. The cells were incubated in medium with NE at a concentration of 100 μM (MCE, HY-13715) according to a previous report (18). The NE group was incubated in medium containing NE for 24 h, whereas

(5) Psychological stress-induced systemic corticosterone directly sabotages intestinal stem cells and exacerbates colitisCell DiscovMay 13, 2025Xiaole Sheng, Lanfei Jin, Zhengrong Yao, Jiaji Gu, Longtao Zhu, Andi Huang, Junxuan Peng, Xin Xu, Xiaolong Ge, Wei Zhou, et al.control mice received vehicle (20% sulfobutylether-β-cyclodextrin). For NE treatment, NE (MedChemExpress, HY-13715) was dissolved in 20% sulfobutylether-β-cyclodextrin and intraperitoneally injected daily for 3 weeks

(6) Benzyl alcohol improves Ang II-induced vascular and renal injuryTurkish Journal of Medical SciencesApril 17, 2025Zhenyu HUA, ZHENYU Huabuffer, and incubated in a 95% O2, 5% CO2 gas environment for over 30 min. Norepinephrine (NE, MCE, HY-13715, USA) was used to induce vasoconstriction, acetylcholine (Ach, MCE, HY-B0282, USA) for endothelium-dependent

(7) Localized propranolol delivery from a copper-loaded hydrogel for enhancing infected burn wound healing via adrenergic β-receptor blockadeMaterials Today BioFebruary 1, 2025Wenzhe Sun, Hongwei Lu, Pengqin Zhang, Lian Zeng, Bing Ye, Yi Xu, Jianan Chen, Peiran Xue, Jialin Yu, Kaifang Chen, et al.well, followed by a replacement of the hydrogel extracts with or without norepinephrine (1 μM) (MCE, HY-13715, NJ, USA). The cells were inspected and imaged at the start and after 24 h using an inverted microscope

(8) Carotid Baroreceptor Stimulation Ameliorates Pulmonary Arterial Remodeling in Rats With Hypoxia‐Induced Pulmonary HypertensionJournal of the American Heart AssociationOctober 1, 2024Xuesheng Fang, Jie Chen, Zhiling Hu, Ling Shu, Jing Wang, Mingyan Dai, Tuantuan Tan, Junxia Zhang, Mingwei Baoof adenovirus vector, and cell transfection, please see Data S1. Chemical Reagents Norepinephrine (HY‐13715), prazosin (HY‐B0193A), U0126 (HY‐12031), recombinant BDNF (brain‐derived neurotrophic factor) protein

(9) Carotid Baroreceptor Stimulation Ameliorates Pulmonary Arterial Remodeling in Rats With Hypoxia‐Induced Pulmonary HypertensionJ Am Heart AssocSeptember 30, 2024Xuesheng Fang, Jie Chen, Zhiling Hu, Ling Shu, Jing Wang, Mingyan Dai, Tuantuan Tan, Junxia Zhang, Mingwei Baoof adenovirus vector, and cell transfection, please see Data S1. Chemical Reagents Norepinephrine (HY‐13715), prazosin (HY‐B0193A), U0126 (HY‐12031), recombinant BDNF (brain‐derived neurotrophic factor) protein

(10) Sleep fragmentation exacerbates myocardial ischemia‒reperfusion injury by promoting copper overload in cardiomyocytesNature CommunicationsMay 7, 2024Na Chen, Lizhe Guo, Lu Wang, Sisi Dai, Xiaocheng Zhu, E. WangCells were all grown at 37 °C in a humid atmosphere of 5%CO2 and 95% air. Norepinephrine (NE, MCE, HY-13715), Phenelzine (MCE, HY-B1018A) and Cucl2 (Sigma, C3279) for treatment of cells were dissolved in DMSO,

(11) Sympathetic innervation induces exosomal miR-125 transfer from osteoarthritic chondrocytes, disrupting subchondral bone homeostasis and aggravating cartilage damage in aging miceJournal of advanced researchMarch 28, 2024Guan Z, Liu Y, Luo L, Jin X, Guan Z, Yang J, Liu S, Tao K, Pan J.osteoblasts or in the bottom chamber of the Transwell system. The cells were cultured in the presence of NE (HY-13715, MCE, USA) for 7–10 days [41]. Molecular modeling and docking In this study, we conducted a docking

(12) Profiling the metabolome of uterine fluid for early detection of ovarian cancerCell Reports MedicineJune 20, 2023Pan Wang, Jihong Ma, Wenjing Li, Qilong Wang, Yinan Xiao, Yuening Jiang, Xiaoyang Gu, Yu Wu, Suwei Dong, Hongyan Guo, et al.,Santa Cruz Biotechnology,Cat#sc-218618 "4-hydroxy-17β-estradiol-1,2,16,16,17-d5",MCE,Cat#HY-146631S Theophylline,MCE,Cat#HY-B0809 Sodium fusidate,MCE,Cat#HY-B1350A Vanillylmandelic acid,MCE,Cat#HY-113121 Norepinephrine,MCE,Cat#HY-13715 Thyroxine,MCE,Cat#HY-18341 Fusidic acid,MCE,Cat#HY-B1350 12S-HHT,MCE,Cat#HY-113330 Arachidonic acid-d8,MCE,Cat#HY-109590S Tetrahydrodeoxycorticosterone-d3,MCE,Cat#HY-113346S "L-glutathione

(13) Glutamine and norepinephrine in follicular fluid synergistically enhance the antioxidant capacity of human granulosa cells and the outcome of IVF-ETScientific ReportsDecember 1, 2022Lulu Wang, Chengliang Zhou, Junyan Sun, Qiuwan Zhang, Dongmei Laicells. And then, glutamine and NE were added into the culture medium of KGN cells for another 48 h. NE (HY-13715, MCE, NJ, USA) was solved in dimethyl sulfoxide (DMSO, Yeasen, shanghai, China) at storage concentrations

(14) Binding pathway determines norepinephrine selectivity for the human β(1)AR over β(2)ARCell researchMay 1, 2021Xu X, Kaindl J, Clark MJ, Hübner H, Hirata K, Sunahara RK, Gmeiner P, Kobilka BK, Liu X.

(15) Melatonin suppresses chronic restraint stress-mediated metastasis of epithelial ovarian cancer via NE/AKT/β-catenin/SLUG axisCell death & diseaseAugust 18, 2020Bu S, Wang Q, Sun J, Li X, Gu T, Lai D.times. Cell Counting Kit-8 (CCK-8) assay The work concentration of SKL2001 (MCE, HY-101085), NE (MCE, HY-13715), KYA1797K (MCE, HY-101090), AKTi VIII (MCE, HY-10355), and MLT (MCE) was determined by CCK-8 assay.

(16) Suppression of Resting Metabolism by the Angiotensin AT2 ReceptorCell reportsAugust 9, 2016Littlejohn NK, Keen HL, Weidemann BJ, Claflin KE, Tobin KV, Markan KR, Park S, Naber MC, Gourronc FA, Pearson NA, et al.

(17) Inhibition of DNA methylation reverses norepinephrine-induced cardiac hypertrophy in ratsCardiovascular researchMarch 1, 2014Xiao D, Dasgupta C, Chen M, Zhang K, Buchholz J, Xu Z, Zhang L.

(18) Adrenergic pharmacology and cognition: focus on the prefrontal cortexPharmacology & therapeuticsMarch 1, 2007Ramos BP, Arnsten AF.

(19) Relative efficacy and potency of beta-adrenoceptor agonists for generating cAMP in human lymphocytesChestJanuary 1, 1996MacGregor DA, Prielipp RC, Butterworth JF 4th, James RL, Royster RL.

(20) Transcatheter arterial embolization in urological tumors: the use of isobutyl-2-cyanoacrylateThe Journal of urologyMay 1, 1979Giuliani L, Carmignani G, Belgrano E, Puppo P.

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Norepinephrine from MedChemExpress

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Norepinephrine from MedChemExpress

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