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Aticaprant
Aticaprant from MedChemExpress
Be the first to write a review!
Citations:
(5)
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Aticaprant
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Description
Aticaprant (CERC-501) is a potent and centrally-penetrant
kappa opioid
receptor antagonist with a
K
i
of 0.807 nM
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Aticaprant
Company
MedChemExpress
Price
$110.00
Supplier Page
View Company Product Page
Catalog Number
HY-101718
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.59%
Type
Chemical
Molecular Weight
418.5
Formula
C₂₆H₂₇FN₂O₂
Research Area
Neurological Disease
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (5)
(1)
Mapping Kappa Opioid Receptor Binding in Titi Monkeys with [ 11 C]GR103545 PET
Molecular Imaging
November 1, 2025
Alita Jesal D Almeida, Brad A. Hobson, Logan E. Savidge, Claudia Manca, John P. Paulus, Karen L. Bales, Abhijit J. Chaudhari
pre-treatment with KOR antagonist CERC-501 (Supplier:
MedChemExpress
, Monmouth Junction, NJ, Cat. No.:
HY-101718
), administered (0.3 mg/kg, i.v.) to the same n = 6
titi monkeys
, 10-min prior to radiotracer administration.
(2)
Kappa opioid receptors diminish spontaneous dopamine signals in awake mice through multiple mechanisms
Neuropharmacology
August 1, 2025
Conner W. Wallace, Katherine M. Holleran, Clare Y. Slinkard, Samuel W. Centanni, Christopher C. Lapish, Sara R. Jones
NIH and dissolved in saline at 1 mg/mL.
Aticaprant
(
MedChemExpress
, Monmouth Junction, NJ; Product:
HY-101718
, CAS: 1174130-61-0) was dissolved in 5% DMSO / 5% Cremophor / 90% saline at 2 mg/mL. 2.6. Theory and
(3)
Kappa Opioid Receptors Negatively Regulate Real Time Spontaneous Dopamine Signals by Reducing Release and Increasing Uptake
bioRxiv
February 11, 2024
Conner W Wallace, Katherine M Holleran, Clare Y Slinkard, Samuel W Centanni, Sara R Jones
between several days of washout. 2.5. Drugs
Aticaprant
(
MedChemExpress
, Monmouth Junction, NJ; Product:
HY-101718
, CAS: 1174130-61-0) was dissolved in 5% DMSO / 5% Cremophor / 90% saline at 2 mg/mL. U50,488H (RTI Log
(4)
Effects of orally-bioavailable short-acting kappa opioid receptor-selective antagonist LY2456302 on nicotine withdrawal in mice
Neuropharmacology
October 1, 2015
Jackson KJ, Jackson A, Carroll FI, Damaj MI.
(5)
LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders
Neuropharmacology
February 1, 2014
Rorick-Kehn LM, Witkin JM, Statnick MA, Eberle EL, McKinzie JH, Kahl SD, Forster BM, Wong CJ, Li X, Crile RS,
et al
.
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Aticaprant from MedChemExpress
Supplier Page
View Company Product Page
$110.00
Product Specs
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