Deferasirox from MedChemExpress

Product Specs
ItemDeferasirox
CompanyMedChemExpress
Price $61.00Supplier Page View Company Product Page
Catalog NumberHY-17359
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.86%
TypeChemical
Molecular Weight373.36
Molecule NameDeferasirox
FormulaC21H15N3O4
Research AreaCancer

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(1) Gestational Trichloroacetic Acid Exposure Induces Miscarriage by Disrupting Iron Homeostasis in Trophoblasts via the KEAP1-NRF2 PathwayEnviron Health (Wash)April 17, 2026Yijun Zhang, Hanyu Rao, Zhiyi Pan, Yan Zhao, Liping Jindissolved in sterilized ddH2O. Deferoxamine mesylate (DFO, Cat. #HY-B0988), Deferasirox (DFX, Cat. #HY-17359), and ML385 (Cat. #HY-100523) were obtained from MedChemExpress (MCE) and prepared following the manufacturer’s

(2) The Achilles’ heel of hepatocellular carcinoma: ginsenoside compound K as a novel GPX4 degrader promotes ferroptosis in hepatocellular carcinomaJournal of Translational MedicineJanuary 27, 2026Yulang Jiang, Peizhen Ma, Yipeng Yang, Xin Shi, Xuling Liu, Mingyu Sun(MedchemExpress, HY-12726), Desferrioxamine(MedchemExpress, HY-B0988), Deferasirox(MedchemExpress, HY-17359),Acetylcysteine(MedchemExpress, HY-B0215), Trolox(MedchemExpress, HY-101445), L-Cysteine(MedchemExpress,

(3) TCF25 serves as a nutrient sensor to orchestrate metabolic adaptation and cell death by enhancing lysosomal acidification under glucose starvationCell reportsSeptember 23, 2025Ren W, Jiang H, Song Q, Chen Y, Tang C, Wang F, Zhu J, Ren J, Zhao Y, He Y, et al.CA-074 methyl ester,MedChemExpress,Cat#HY-100350 BAY-876,MedChemExpress,Cat#HY-100017 Deferoxamine,MedChemExpress,Cat#HY-B1625 Deferasirox,MedChemExpress,Cat#HY-17359 Ouabain,MedChemExpress,Cat#HY-B0542 Concanamycin A,MedChemExpress,Cat#HY-N1724 Recombinant mouse

(4) Iron supplementation alleviates pathologies in a mouse model of facioscapulohumeral muscular dystrophyJournal of Clinical InvestigationSeptember 2, 2025Kodai Nakamura, Huascar Pedro Ortuste Quiroga, Naoki Horii, Shin Fujimaki, Toshiro Moroishi, Keiichi I. Nakayama, Shinjiro Hino, Yoshihiko Saito, Ichizo Nishino, Yusuke Ono(D9533, Sigma-Aldrich) dissolved in PBS was intraperitoneally injected (300 mg/kg body weight). DFX (HY-17359, MedChemExpress) dissolved in corn oil was administered via oral gavage at a dose of 20 mg/kg body weight.

(5) Potent antioxidant and mitochondrial-protective effects of ATH434, a moderate affinity iron chaperoneThe Journal of biological chemistrySeptember 1, 2025Bailey DK, Nihlawi R, Bradbury MJ, Bond S, Kosman DJ.ATH434-met were provided by Alterity Therapeutics (Melbourne, AUS). DFP (Cat. #HY-B0568), DFX (Cat. #HY-17359), 8-Quinolinol (Cat. #HY-B1005) were purchased from MedChemExpress. Trolox (Cat. #10011659) and a-tocopherol

(6) Iron supplementation alleviates pathologies in a mouse model of facioscapulohumeral muscular dystrophyJ Clin InvestJuly 1, 2025Kodai Nakamura, Huascar Pedro Ortuste Quiroga, Naoki Horii, Shin Fujimaki, Toshiro Moroishi, Keiichi I. Nakayama, Shinjiro Hino, Yoshihiko Saito, Ichizo Nishino, Yusuke Ono(D9533, Sigma-Aldrich) dissolved in PBS was intraperitoneally injected (300 mg/kg body weight). DFX (HY-17359, MedChemExpress) dissolved in corn oil was administered via oral gavage at a dose of 20 mg/kg body weight.

(7) Nanoparticle-Mediated Delivery of Deferasirox: A Promising Strategy Against Invasive AspergillosisBioengineering (Basel)November 5, 2024Sydney Peppe, Moloud Farrokhi, Evan A. Waite, Mustafa Muhi, Efthymia Iliana Matthaiouof PLGA NPs, we employed a single emulsion solvent evaporation technique. Briefly, DFX (10 mg/mL) (HY-17359 MedChemExpress, Monmouth Junction, NJ, USA) was dissolved in Dimethyl Sulfoxide (DMSO) (BP231100, Fisher Bioreagents

(8) Super-enhancer-driven MLX mediates redox balance maintenance via SLC7A11 in osteosarcomaCell death & diseaseJuly 17, 2023Guo W, Wang X, Lu B, Yu J, Xu M, Huang R, Cheng M, Yang M, Zhao W, Zou C.(HY-14655), Liproxstatin-1 (HY-12726), Ferrostatin-1 (HY-100579), Deferoxamine/DFO (HY-B0988), Deferasirox (HY-17359), and Dimethyl sulfoxide/DMSO (HY-Y0320), all purchased from MCE. Invasion assay 143B and SJSA1 cells

(9) Inconsistent hepatic antifibrotic effects with the iron chelator deferasiroxJournal of gastroenterology and hepatologyMarch 1, 2015Sobbe A, Bridle KR, Jaskowski L, de Guzman CE, Santrampurwala N, Clouston AD, Campbell CM, Subramaniam VN, Crawford DH.

(10) Deferasirox shows in vitro and in vivo antileukemic effects on murine leukemic cell lines regardless of iron statusExperimental hematologyJune 1, 2013Lee DH, Jang PS, Chung NG, Cho B, Jeong DC, Kim HK.

(11) The oral iron chelator deferasirox induces apoptosis in myeloid leukemia cells by targeting caspaseActa haematologicaJanuary 1, 2011Kim JL, Kang HN, Kang MH, Yoo YA, Kim JS, Choi CW.

(12) Two iron-sulfur centers in mitochondrial outer membranes from beef heart as prepared by free-flow electrophoresisFEBS lettersNovember 15, 1978Heidrich HG, Albracht SP, Bäckstrom D.

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Deferasirox from MedChemExpress

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Deferasirox from MedChemExpress

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