ITX3 from MedChemExpress | Biocompare.com

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ITX3

Description

ITX3 is a specific and nontoxic inhibitor of TrioN (N-terminal GEF domain of the multidomain Trio protein) with an IC₅₀ value of 76 µM. ITX3 can be used for the research of agent

Product Specs
ItemITX3
CompanyMedChemExpress
Price $74.00Supplier Page View Company Product Page
Catalog NumberHY-16663
Quantity5 mg
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity98.60%
TypeChemical
Molecular Weight371.45
FormulaC₂₂H₁₇N₃OS
Research AreaOthers

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(1) Tara up-regulates E-cadherin transcription by binding to the Trio RhoGEF and inhibiting Rac signalingThe Journal of cell biologyApril 18, 2011Yano T, Yamazaki Y, Adachi M, Okawa K, Fort P, Uji M, Tsukita S, Tsukita S.

(2) A cell active chemical GEF inhibitor selectively targets the Trio/RhoG/Rac1 signaling pathwayChemistry & biologyJune 26, 2009Bouquier N, Vignal E, Charrasse S, Weill M, Schmidt S, Léonetti JP, Blangy A, Fort P.

(3) RFLP at the bovine phosphogluconate dehydrogenase (PGD) locusAnimal geneticsJanuary 1, 1992Beever JE, Lewin HA.

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