PHTPP from MedChemExpress

Product Specs
ItemPHTPP
CompanyMedChemExpress
Price $66.00Supplier Page View Company Product Page
Catalog NumberHY-103456
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.70%
TypeChemical
Molecular Weight423.31
FormulaC₂₀H₁₁F₆N₃O
Research AreaCancer

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(1) The synthetic estradiol analog E0703 enhances Akkermansia muciniphila growth for radiation‐induced intestinal damage repairmLifeApril 30, 2026Zhexin Ni, Ziqiao Yan, Mingyang Chang, Yangshuo Li, Zebin Liao, Tiantian Xia, Zhijie Bai, Ningning Wang, Chaoji Huangfu, Dezhi Sun, et al.antagonist 4‐[2‐Phenyl‐5,7‐bis(trifluoromethyl)pyrazolo[1,5‐a]pyrimidin‐3‐yl]phenol (PHTPP) (1 μM, MCE, HY‐103456) in combination with E0703 (60 ng/ml). A fourth group was treated with GlcN‐6‐P (10 μM, G5509; Merck)

(2) Estetrol Enhances Mitochondrial Bioenergetics and Neurite Outgrowth in Cellular Models of Alzheimer's DiseaseCellsMarch 3, 2026Amandine Grimm, Aurélien Riou, Clara Gaillard, Aline Broeglin, Rodrigo Portes Ureshino, Valérie Dion, Céline Gérard, Anne Eckert(PFA, #P6148) were all obtained from Sigma Aldrich (St. Louis, MO, USA). MPP (#HY-103454), PHTPP (#HY-103456), Fulvestrant (#HY-103636) and G-15 (#HY-103449) were obtained from MedChemExpress (Monmouth Junction,

(3) 17-β-Estradiol Protects Chondrocytes From Senescence and Ameliorates Osteoarthritis Progression via ERα-AKT-FOXO4 PathwayJ Cell Mol MedFebruary 12, 2026Yikai Liu, Jiangshan Ai, Zian Zhang, Xinzhe Lu, Chaoqun Yu, Yejun Zha, Haining Zhang[31]. To block ERα, 20 μM TPBM (MCE, HY‐131404) was used for 24 h [32]. To block ERβ, 1 μM PHTPP (MCE, HY‐103456) was used for 24 h. To block GPER, 1 μM G15 (MCE, HY‐103449) was used for 48 h [32, 33, 34, 35]. To

(4) Oroxylin A may promote cell apoptosis and inhibit epithelial-mesenchymal transition in endometrial cancer, associated with the ERβ/PI3K/AKT pathwaySci RepApril 10, 2025Xue Fan, Luming Wu, Tong Cheng, Weilong Lv, Jiao Tian, Jijun Tao, Shiyan Tu, Fangjun Tan, Yiqing Wang284.263, purity ≥ 99%) was sourced from Shanghai Standard Technology Co., Ltd. (Shanghai, China). PHTPP (HY-103456) was sourced from MedChemExpress (Monmouth Junction, NJ). DMEM medium was purchased from Biosharp (Hefei,

(5) Profiling estrogen, progesterone, and androgen receptors in colorectal cancer in relation to gender, menopausal status, clinical stage, and tumour sidednessFrontiers in endocrinologyJanuary 1, 2023Refaat B, Aslam A, Idris S, Almalki AH, Alkhaldi MY, Asiri HA, Almaimani RA, Mujalli A, Minshawi F, Alamri SA, et al.hormones, alongside the specific receptor blockers of ERα (MPP dihydrochloride; #HY-103454), ERβ (PHTPP; #HY-103456), PGR (mifepristone; #HY-13683), and AR (bicalutamide; #HY-14249) were obtained from MedChemExpress

(6) Glutamatergic and GABAergic neurons in the preoptic area of the hypothalamus play key roles in menopausal hot flashesFrontiers in aging neuroscienceJanuary 1, 2022Sun Y, Wang H, Wang W, Lu J, Zhang J, Luo X, Luan L, Wang K, Jia J, Yan J, et al.randomly selected from SHAM group and OVX + E group of ERβ group to inject antagonists of ERβ (PHTPP, HY-103456, MedChemExpress) into POA, and five rats from OVX group were randomly selected to inject agonists of

(7) IGF-1 gene expression is differentially regulated by estrogen receptors α and β in mouse endometrial stromal cells and ovarian granulosa cellsThe Journal of reproduction and developmentJanuary 1, 2014Ogo Y, Taniuchi S, Ojima F, Hayashi S, Murakami I, Saito Y, Takeuchi S, Kudo T, Takahashi S.

(8) Pyrazolo[1,5-a]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activityJournal of medicinal chemistryNovember 18, 2004Compton DR, Sheng S, Carlson KE, Rebacz NA, Lee IY, Katzenellenbogen BS, Katzenellenbogen JA.

(9) A comparative study of the accuracy of Ranawat's and Pierchon's methods to determine the centre of rotation in bilateral coxopathySkeletal radiologyNovember 1, 2000Olmedo-Garcia N, Lopez-Prats F, Agullo A, Ortuño A, Palazon A.

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