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Protein Biochemistry
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Ribociclib hydrochloride
Ribociclib hydrochloride from MedChemExpress
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Citations:
(4)
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Ribociclib hydrochloride
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Description
Ribociclib hydrochloride (LEE011 hydrochloride) is a highly specific
CDK4/6
inhibitor with
IC
50
values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Ribociclib hydrochloride
Company
MedChemExpress
Price
$87.00
Supplier Page
View Company Product Page
Catalog Number
HY-15777A
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.95%
Type
Chemical
Molecular Weight
471.00
Molecule Name
Ribociclib hydrochloride
Formula
C23H31ClN8O
Research Area
Cancer
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (4)
(1)
CDK6-mediated endothelial cell cycle acceleration drives arteriovenous malformations in hereditary hemorrhagic telangiectasia
Nature Cardiovascular Research
November 1, 2024
Sajeth Dinakaran, Sima Qutaina, Haitian Zhao, Yuefeng Tang, Zhimin Wang, Santiago Ruiz, Aya Nomura-Kitabayashi, Christine N. Metz, Helen M. Arthur, Stryder M. Meadows,
et al.
mg kg−1,
MedChemExpress
,
HY-A0065
) in saline, ribociclib hydrochloride (100 mg kg−1,
MedChemExpress
,
HY-15777A
) in 10% DMSO, 20%
SBE-β-CD
(
MedChemExpress
,
HY-17031
) in saline, samuraciclib hydrochloride hydrate
(2)
CDK6-mediated endothelial cell cycle acceleration drives arteriovenous malformations in hereditary hemorrhagic telangiectasia
bioRxiv : the preprint server for biology
September 16, 2023
Dinakaran S, Zhao H, Tang Y, Wang Z, Ruiz S, Nomura-Kitabayashi A, Blanc L, Faughnan ME, Marambaud P.
(
MedChemExpress
,
HY-A0065
) in saline (100 mg/kg) or with ribociclib hydrochloride (
MedChemExpress
,
HY-15777A
) in 10% DMSO, 20%
SBE-β-CD
(
MedChemExpress
,
HY-17031
) in saline (100 mg/kg).
Mice
were maintained in
(3)
Molecular Pathways: Targeting the Cyclin D-CDK4/6 Axis for Cancer Treatment
Clinical cancer research : an official journal of the American Association for Cancer Research
July 1, 2015
VanArsdale T, Boshoff C, Arndt KT, Abraham RT.
(4)
Dual CDK4/CDK6 inhibition induces cell-cycle arrest and senescence in neuroblastoma
Clinical cancer research : an official journal of the American Association for Cancer Research
November 15, 2013
Rader J, Russell MR, Hart LS, Nakazawa MS, Belcastro LT, Martinez D, Li Y, Carpenter EL, Attiyeh EF, Diskin SJ,
et al
.
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Ribociclib hydrochloride from MedChemExpress
Supplier Page
View Company Product Page
$87.00
Product Specs
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