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Protein Biochemistry
Chemicals and Reagents
NSC232003
NSC232003 from MedChemExpress
Be the first to write a review!
Citations:
(4)
Supplier Page
Supplier Page from
MedChemExpress for
NSC232003
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Description
NSC232003 is a highly potent and cell-permeable
UHRF1
inhibitor, which inhibits DNA methylation in vitro and disrupts DNMT1/UHRF1 interactions at a cellular level
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
NSC232003
Company
MedChemExpress
Price
$279.00
Supplier Page
View Company Product Page
Catalog Number
HY-103236
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.94%
Type
Chemical
Molecular Weight
169.14
Formula
C₆H₇N₃O₃
Research Area
Cancer
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (4)
(1)
A Hybrid compound H93 treats prostate cancer by directly binding UHRF1 and promoting protein dimerization
Communications Chemistry
November 18, 2025
Yuxin Fu, Longying Jiang, Guojian Xie, Yuchong Peng, Yongming Fu, Qianling Zhu, Youhong Liu, Guilong Zhao, Xueke Liu, Yongbo Peng,
et al.
Nature Portfolio Reporting Summary linked to this article. Reagents
UHRF1
inhibitor
NSC232003
(Cat#
HY-103236
), PARP inhibitor olaparib (Cat#
HY-10162
) and androgen receptor
inhibitor
enzalutamide (Cat#
HY-70002
)
(2)
NKX2-5/LHX1 and UHRF1 Establishing a Positive Feedback Regulatory Circuitry Drives Esophageal Squamous Cell Carcinoma through Epigenetic Dysregulation
Adv Sci (Weinh)
April 30, 2025
Xukun Li, Dandan Fan, Yong Li, Jian Yuan, Wanyuan Sun, Qinghao Zhu, Ling Qi, Xueling Wu, Jiahui Cai, Tongyang Gong,
et al.
inhibitor
treatment, after the cell confluence reached 60%, the cells were treated with
NSC232003
(
HY‐103236
,
MCE
) or its vehicle control for 24 h. RNA Isolation and
Quantitative Real‐Time PCR
Total RNA was
(3)
Novel role of UHRF1 in the epigenetic repression of the latent HIV-1
eBioMedicine
May 1, 2022
Roxane Verdikt et al.
epigallocatechin-3-gallate (EGCG, E4143) were purchased from
Sigma Aldrich
.
NSC232003
was purchased from
MedChemExpress
(
HY-103236
). Antibodies against CREB (
sc-186
, RRID:AB_2086021), CREM (
sc-440
, RRID:AB_673599), ATF-1 (
sc-28673
,
(4)
Tandem virtual screening targeting the SRA domain of UHRF1 identifies a novel chemical tool modulating DNA methylation
European journal of medicinal chemistry
May 23, 2016
Myrianthopoulos V, Cartron PF, Liutkevičiūtė Z, Klimašauskas S, Matulis D, Bronner C, Martinet N, Mikros E.
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NSC232003 from MedChemExpress
Supplier Page
View Company Product Page
$279.00
Product Specs
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