VAS2870 from MedChemExpress

Product Specs
ItemVAS2870
CompanyMedChemExpress
Price $73.00Supplier Page View Company Product Page
Catalog NumberHY-12804
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity98.79%
TypeChemical
Molecular Weight360.39
FormulaC₁₈H₁₂N₆OS
Research AreaCardiovascular Disease

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(1) Hepatocyte-Derived IL-25 Promotes Macrophage Extracellular Trap Formation and Drives Liver Fibrosis ProgressionInflammationApril 1, 2026Cheng-Jiang Cao, Ming Yang, Chang-Lin Du, Xue Fang, He-Hang Song, Wen-Jing Wang, Miao-Miao Wang, Wen-Mei Zhang, Zhen-Long Liu, Cheng Huang, et al.(3,6-Dithia-1,8-octanediol) (CAS: 5244–34-8, Santa Cruz Biotechnology, USA), 25 μM VAS2870 (Cat. No. HY-12804; MedChemExpress, NJ, USA), 1U/ml DNase I (Cat. No. EN0521; Thermo Scientific, USA). Mouse Models of

(2) Pre-eclampsia-related TLR2/4 signaling activates NOX2/4 to induce oxidative stress and ferroptosis in trophoblastsEuropean Journal of Medical ResearchDecember 15, 2025Yan Zhang, Yunmei Ke, Baosheng Zhu, Zhuo Chen, Li Ren, Jinman Zhang, Jie Wuand 95% air for 24 h re-oxygenation. Robinin (TLR2/4 inhibitor, HY-N1346) and VAS2870 (NOX inhibitor, HY-12804) were purchased from MedChemExpress (Shanghai, China). The concentration used for Robinin (10 μM) was

(3) Cancer Cell‐Derived Large Extracellular Vesicles Promote Venous Thromboembolism by Activating NETosis Through Delivering CYBAAdvanced ScienceJuly 21, 2025Xiangji Li, Yingjiao Ju, Chenjie Xu, Shixiang Ma, Lan Sun, Qingdong Guo, Mingyuan Liu, Yibin Xie, Li Minparticle/kg), MC38‐KO cyba ‐lEVs (1.6 × 1011 particle/kg), and MC38‐lEVs plus ROS inhibitor (VAS2870, HY‐12804, MCE, USA) (1.6×1011 particle/kg plus 2.5 mg kg−1). All mice were injected lEVs suspension or ROS inhibitor

(4) Endoplasmic Reticulum Stress and Unfolded Protein Response Sensor ERN1 Regulates Organic Dust Induction of Lung InflammationFASEB bioAdvancesJuly 1, 2025Kusampudi S, Meganathan V, Boggaram V.epithelial cell inflammatory response. 2 Materials and Methods 2.1 Chemicals and Reagents VAS2870 (HY12804, MedChemExpress, NJ, USA) was used as a pan‐NOX inhibitor. Toll‐like receptor 2 (TLR2) inhibitor CU CPT 22

(5) Inhibition of the NADPH Oxidase Pathway Reduces Ferroptosis during Septic Renal Injury in Diabetic MiceOxidative Medicine and Cellular LongevityFebruary 27, 2022Weifeng Yao, Haofeng Liao, Mengya Pang, Lijie Pan, Yu Guan, Xiaolei Huang, Ziqing Hei, Chenfang Luo, Mian GeMedChemExpress, USA) or vehicle 1 h before LPS administration. For NADPH oxidase inhibition, Vas2870 (10 mg/kg, HY-12804, MedChemExpress, USA) or vehicle was injected intraperitoneally 3 h before LPS administration. Twenty-four

(6) D-4F Ameliorates Contrast Media-Induced Oxidative Injuries in Endothelial Cells via the AMPK/PKC PathwayFrontiers in pharmacologyJanuary 1, 2020Guo Y, Li W, Qian M, Jiang T, Guo P, Du Q, Lin N, Xie X, Wu Z, Lin D, et al.and HRP-goat antimouse IgG (MBL 330, MBL). Compound C (S7306, Selleck Chemicals, TX, USA), VAS2870 (HY-12804, MedChemExpress, NJ, USA), L-NAME (HY-18729A, MedChemExpress), D-4F (purity 95%, China Peptide Company,

(7) The NADPH oxidase inhibitor VAS2870 impairs cell growth and enhances TGF-β-induced apoptosis of liver tumor cellsBiochemical pharmacologyApril 1, 2011Sancho P, Fabregat I.

(8) Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferationCardiovascular researchJuly 15, 2006ten Freyhaus H, Huntgeburth M, Wingler K, Schnitker J, Bäumer AT, Vantler M, Bekhite MM, Wartenberg M, Sauer H, Rosenkranz S.

(9) Electrical properties of commercial concentric EMG electrodesMuscle & nerveJanuary 1, 1985Dorfman LJ, McGill KC, Cummins KL.

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VAS2870 from MedChemExpress

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VAS2870 from MedChemExpress

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