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Protein Biochemistry
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Propofol
Propofol from MedChemExpress
Be the first to write a review!
Citations:
(10)
Supplier Page
Supplier Page from
MedChemExpress for
Propofol
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Description
Propofol potently and directly activates
GABA
A
receptor and inhibits glutamate receptor mediated excitatory synaptic transmission. Propofol has antinociceptive properties and is used for sedation and hypnotic
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Propofol
Company
MedChemExpress
Price
$61.00
Supplier Page
View Company Product Page
Catalog Number
HY-B0649
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.52%
Type
Chemical
Molecular Weight
178.27
Molecule Name
Propofol
Formula
C12H18O
Research Area
Neurological Disease; Cancer
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (10)
(1)
Effects of adjuvant propofol on antitumoral effects of carboplatin in experimental endometrial cancer: possible epigenetic associations
Scientific Reports
May 21, 2026
Çevik Gürel, Gökçe Ceren Kuşçu, Aylin Buhur, Saadet Özen Akarca Dizakar, Hale Güler Kara, Neslihan Pınar Özateş, Nuri Yıldırım, İlkben Günüşen
viability, proliferation, migration, and molecular
assays
. HES+
Propofol
Cells were treated with propofol (
HY-B0649
-100 mg;
MedChemExpress
, New Jersey, USA) at a final working concentration of 4 µg/mL5 in complete culture
(2)
High-Dose Propofol Induces Cytotoxicity by Elevating Intracellular Ca2⁺ via GABAA Receptor and IP3R in HT22 Cells
Drug Des Devel Ther
March 10, 2026
Hao Zhou, Huimin Zhou, Xi Tan, Yadong Jin, Tin Yin Choi, Chaoxuan Dong
(Montclair, California, USA). CCK-8
assay
(K1018/CK04) was purchased from APExBIO (Houston, USA).
Propofol
(
HY-B0649
, purity ≥ 99%) and
Bicuculline
(HY-N021) were purchased from
MCE
(New Jersey, USA).
EGTA
(SA8500) was
(3)
High-Dose Propofol Induces Cytotoxicity by Elevating Intracellular Ca2⁺ via GABAA Receptor and IP3R in HT22 Cells
Drug Des Devel Ther
March 10, 2026
Hao Zhou, Huimin Zhou, Xi Tan, Yadong Jin, Tin Yin Choi, Chaoxuan Dong
(Montclair, California, USA). CCK-8
assay
(K1018/CK04) was purchased from APExBIO (Houston, USA).
Propofol
(
HY-B0649
, purity ≥ 99%) and
Bicuculline
(HY-N021) were purchased from
MCE
(New Jersey, USA).
EGTA
(SA8500) was
(4)
Propofol upregulates MFG‑E8 in BV2 cells to inhibit pyroptosis mediated by the NF‑κB/NLRP3 pathway, thereby ameliorating ischemic‑reperfusion neuronal injury
Int J Mol Med
March 5, 2026
Shewei Guo, Yingwei Zhen, Guosheng Zhou, Zhihua Zhao
OGD/R cell model (29). In addition, for the PPF group, PPF (2, 4, 8, 16, 32, 64 and 128 μM, cat. no.
HY-B0649
,
MedChemExpress
) was added to the culture medium during reoxygenation (30). In subsequent experiments,
(5)
Functional analysis of the effects of propofol on tamoxifen‑resistant breast cancer cells: Insights into transcriptional regulation
Oncology Letters
February 21, 2025
Runyang Yin, Jing Gao, Yang Liu, Chunyan Guo
targets for the treatment of TR
breast cancer
. Materials and methods Materials
Propofol
(cat. no.
HY-B0649
) and TAM (cat. no.
HY-13757A
) were purchased from
MedChemExpress
. For the experiments, propofol and
(6)
Propofol reduces lipopolysaccharide‑induced cardiomyocyte injury in sepsis by activating SIRT1‑mediated autophagy
Experimental and Therapeutic Medicine
March 14, 2023
Junwang Du, Yan Zhou
HY-D1056
;
MedChemExpress
) for 24 h at 37˚C (16). Concentrations of 12.5, 25 and 50 µM propofol (cat. no.
HY-B0649
;
MedChemExpress
) were selected to pretreat H9C2 cells at 37˚C for 24 h prior to LPS treatment (8,17).
(7)
Propofol suppresses adipose-derived stem cell progression via PI3K/AKT-Wnt signaling pathway
BMC anesthesiology
March 9, 2022
Yin G, Wang J, Zhong Y, Wu W.
proliferation [14]. Each group was set up with three parallels.
Propofol
was purchased from
MedChemExpress
(No.
HY-B0649
). The cells were digested and pipetted into a single cell suspension, counted, and inoculated in a 96-well
(8)
Antinociceptive properties of propofol: involvement of spinal cord gamma-aminobutyric acid(A) receptors
The Journal of pharmacology and experimental therapeutics
September 1, 1997
Nadeson R, Goodchild CS.
(9)
[A case of periarteritis nodosa after implantation of disulfiram]
Acta clinica Belgica
January 1, 1975
Telerman-Toppet N, Vanaise A, Six R, Vanherweghem JL, Sternon J, Coers C.
(10)
Propofol Inhibits Microglial Activation via miR-106b/Pi3k/Akt Axis
Frontiers in cellular neuroscience
January 1, 0001
"Liu J, Ai P, Sun Y, Yang X, Li C, Liu Y, Xia X, Zheng JC."
purchased from Sigma (Cat # L2880) and dissolved in PBS.
Propofol
was purchased from
MedChemExpress
(Cat #
HY-B0649
) and dissolved in DMSO. For LPS stimulation, primary
microglia
and BV2 cells were pre-treated with LPS
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Propofol from MedChemExpress
Supplier Page
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$61.00
Product Specs
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