DMNQ from MedChemExpress

Product Specs
ItemDMNQ
CompanyMedChemExpress
Price $82.00Supplier Page View Company Product Page
Catalog NumberHY-121026
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.8%
TypeChemical
Molecular Weight218.21
FormulaC₁₂H₁₀O₄
Research AreaCardiovascular Disease

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(1) ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 SignalingAdvanced ScienceMarch 1, 2026Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, et al.tert‐butyl hydroperoxide (tBOOH, MACKLIN, #B802372‐50 mL); 2,3‐dimethoxy‐1,4‐naphthalenedione (DMNQ, MCE, #HY‐121026); MG‐132 (MCE, #HY‐13259); Z‐VAD (MCE, #HY‐16658B); CuCl2 (Macklin, #C804816); Elesclomol (Macklin,

(2) Eburicoic acid inhibits endothelial cell pyroptosis and retards the development of atherosclerosis through the Keap1/Nrf2/HO‑1/ROS pathwayMolecular medicine reportsJuly 1, 2025Ma MQ, Yang C, Jin SY, Yang Y, Pan YY, Lin XH.pyroptosis. Besides, cells were pre-incubated with 10 µM DMNQ (ROS agonist; MedChemExpress; cat. no. HY-121026) for 6 h to increase ROS production. Small interfering RNA (siRNA) transfection siRNA targeting HO-1

(3) Atractylenolide I Inhibits Nicotine-Induced Macrophage Pyroptosis and Alleviates Atherogenesis by Suppressing the TLR4/ROS/TXNIP/NLRP3 PathwayMetabolitesMay 15, 2025Li HH, Liu X, Wang YP, Xu X, Zhu L, Zhang W, Ren K.for synchronization. To increase ROS production, cells were incubated with 10 µM DMNQ (ROS agonist, #HY-121026, MedChemExpress) for 6 h. For the overexpression of TLR4 and TXNIP, macrophages were transfected with

(4) A mitochondrial EglN1-AMPKα axis drives breast cancer progression by enhancing metabolic adaptation to hypoxic stressThe EMBO journalOctober 16, 2023Jiang W, Zhang M, Gao C, Yan C, Gao R, He Z, Wei X, Xiong J, Ruan Z, Yang Q, et al.inhibitor, S7840) were from Selleck. Deferoxamine (DFO, HY‐B0988), 2,3‐Dimethoxy‐1,4‐naphthoquinone (DMNQ, HY‐121026), and PT2399 (HY‐108697) were from MedChemExpress. The above reagents were used at the indicated doses

(5) Autoxidation of extracellular hydroquinones is a causative event for the cytotoxicity of menadione and DMNQ in A549-S cellsArchives of biochemistry and biophysicsMarch 1, 2003Watanabe N, Forman HJ.

(6) Quinone-induced oxidative stress elevates glutathione and induces gamma-glutamylcysteine synthetase activity in rat lung epithelial L2 cellsThe Journal of biological chemistryOctober 21, 1994Shi MM, Kugelman A, Iwamoto T, Tian L, Forman HJ.

(7) The relationship of alpha-L-iduronidase and Hurler corrective factorArchives of biochemistry and biophysicsJanuary 1, 1976Shapiro LJ, Hall CW, Leder IG, Neufeld EF.

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DMNQ from MedChemExpress

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