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Protein Biochemistry
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Risdiplam
Risdiplam from MedChemExpress
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Citations:
(4)
Supplier Page
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MedChemExpress for
Risdiplam
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Description
Risdiplam (RG7916) is an orally administered, centrally and peripherally distributed
SMN2
pre-mRNA splicing modifier that increases survival motor neuron (SMN) protein levels
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Risdiplam
Company
MedChemExpress
Price
$165.00
Supplier Page
View Company Product Page
Catalog Number
HY-109101
Quantity
5 mg
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.64%
Type
Chemical
Molecular Weight
401.46
Molecule Name
Risdiplam
Formula
C22H23N7O
Research Area
Neurological Disease
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (4)
(1)
PMS1 as a target for splice modulation to prevent somatic CAG repeat expansion in Huntington's disease
bioRxiv
July 30, 2023
Zachariah L. McLean, Dadi Gao, Kevin Correia, Jennie C. L. Roy, Shota Shibata, Iris N. Farnum, Zoe Valdepenas-Mellor, Manasa Rapuru, Elisabetta Morini, Jayla Ruliera,
et al.
LMI070, NVS-SM1) (
MedChemExpress
,
HY-19620
,) or risdiplam (Synonyms: RG7916; RO7034067) (
MedChemExpress
,
HY-109101
) treatments, a 1 mM stock solution prepared in DMSO was diluted in media to the concentrations indicated
(2)
Splicing activates transcription from weak promoters upstream of alternative exons
Nature Communications
June 10, 2023
Maritere Uriostegui-Arcos, Steven T. Mick, Zhuo Shi, Rufuto Rahman, Ana Fiszbein
puromycin (
Gibco
,
A1113802
) at 1 ug/mL for 2 weeks. Cells were treated with
Risdiplam
(
MedChemExpress
,
HY-109101
, soluble in ethanol) at various concentrations (0.1 μM, 1 μM, and 10 μM) for 24 h. Control cells were
(3)
Moxifloxacin rescues SMA phenotypes in patient-derived cells and animal model
Cellular and molecular life sciences : CMLS
July 22, 2022
Januel C, Menduti G, Mamchaoui K, Martinat C, Artero R, Konieczny P, Boido M.
10 days, the cell viability was quantified.
Moxifloxacin
(Cat. No.:
HY-66011
), risdiplam (Cat. No.:
HY-109101
) were provided by
MedChemExpress
, while kenpaullone (Cat. No.:
1398
) was provided by
Tocris
. Immunostaining After
(4)
Risdiplam distributes and increases SMN protein in both the central nervous system and peripheral organs
Pharmacology research & perspectives
December 1, 2018
Poirier A, Weetall M, Heinig K, Bucheli F, Schoenlein K, Alsenz J, Bassett S, Ullah M, Senn C, Ratni H,
et al
.
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Risdiplam from MedChemExpress
Supplier Page
View Company Product Page
$165.00
Product Specs
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