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Protein Biochemistry
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MS417
MS417 from MedChemExpress
Be the first to write a review!
Citations:
(3)
Supplier Page
Supplier Page from
MedChemExpress for
MS417
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Description
MS417 is a selective BET-specific
BRD4
inhibitor, binds to BRD4-BD1 and BRD4-BD2 with
IC
50
s of 30, 46 nM and
K
d
s of 36.1, 25.4 nM, respectively, with weak selectivity at CBP BRD (
IC
50
, 32.7 µM)
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
MS417
Company
MedChemExpress
Price
$80.00
Supplier Page
View Company Product Page
Catalog Number
HY-111139
Quantity
5 mg
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.79%
Type
Chemical
Molecular Weight
414.91
Formula
C₂₀H₁₉ClN₄O₂S
Research Area
Inflammation/Immunology; Infection
Add to Compare List
MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (3)
(1)
Distal enhancers regulate mammalian early embryonic lineage differentiation through long-range interactions
Nucleic Acids Research
January 21, 2026
Qianshu Zhu, Shimeng Guo, Juan Xie, Jiadan Qu, Xiaoyu Wan, Sicong Liang, Xiaoyu Liu, Ling Zhu, Jie Wang, Sheng Yang,
et al.
(
MR-121-D
,
Millipore
, Merck, Germany) containing 10 μM A485 (
HY-107455
,
MedChemExpress
) and 4 μM
MS417
(
HY-111139
,
MedChemExpress
), respectively, up to the blastocyst stage. Morula and blastocyst stage embryos were
(2)
Promotion of HIV clearance by sensitization of HIV reservoirs to cell death
Front Immunol
July 14, 2025
Min Li, Baichao Sun, Jing Dong, Jian-Rong Li, Laurie J. Minze, Min Chen, Chao Cheng, Jin Wang
and cell killing, latently infected CD4+ T cells were treated for 48 h with 3 μM
JQ1
or 1 μM
MS417
(
HY-111139
,
MedChemExpress
), respectively, or with 50 nM
ABT-263
and 2 μM
SAR405
. The cells were then incubated
(3)
Down-regulation of NF-κB transcriptional activity in HIV-associated kidney disease by BRD4 inhibition
The Journal of biological chemistry
August 17, 2012
Zhang G, Liu R, Zhong Y, Plotnikov AN, Zhang W, Zeng L, Rusinova E, Gerona-Nevarro G, Moshkina N, Joshua J,
et al
.
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MS417 from MedChemExpress
Supplier Page
View Company Product Page
$80.00
Product Specs
Company Info
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