Torcetrapib from MedChemExpress | Biocompare.com

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Torcetrapib

Description

Torcetrapib (CP-529414) is a selective, potent cholesteryl ester transfer protein (CETP) inhibitor. A typical inhibition curve for whole human plasma, having a CETP concentration of 37 nM

Product Specs
ItemTorcetrapib
CompanyMedChemExpress
Price $106.00Supplier Page View Company Product Page
Catalog NumberHY-12089
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.88%
TypeChemical
Molecular Weight600.47
Molecule NameTorcetrapib
FormulaC26H25F9N2O4
Research AreaEndocrinology

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(1) Identification of CETP as a molecular target for estrogen positive breast cancer cell death by cholesterol depleting agentsGenes & cancerSeptember 1, 2016Esau L, Sagar S, Bangarusamy D, Kaur M.

(2) Selective CETP inhibition and PPARalpha agonism increase HDL cholesterol and reduce LDL cholesterol in human ApoB100/human CETP transgenic miceJournal of cardiovascular pharmacology and therapeuticsJune 1, 2010Hansen MK, McVey MJ, White RF, Legos JJ, Brusq JM, Grillot DA, Issandou M, Barone FC.

(3) Raising high-density lipoprotein in humans through inhibition of cholesteryl ester transfer protein: an initial multidose study of torcetrapibArteriosclerosis, thrombosis, and vascular biologyMarch 1, 2004Clark RW, Sutfin TA, Ruggeri RB, Willauer AT, Sugarman ED, Magnus-Aryitey G, Cosgrove PG, Sand TM, Wester RT, Williams JA, et al.

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