Triapine from MedChemExpress

Product Specs
ItemTriapine
CompanyMedChemExpress
Price $73.00Supplier Page View Company Product Page
Catalog NumberHY-10082
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.78%
TypeChemical
Molecular Weight195.24
Molecule Name3-AP
FormulaC7H9N5S
Research AreaCancer

Add to Compare List

MedChemExpress

1 Deer Park Drive, Suite F

MONMOUTH JUNCTION, NJ 08852

United States

Phone: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910

Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com

Company Profile

Website: medchemexpress.com

(1) Ribonucleotide Reductase Inhibition Overcomes FLT3 Inhibitor Resistance in Acute Myeloid LeukemiabioRxivJuly 22, 2026Zhen Tian, Xiaoyu Wei, Srinivas Chatla, Yang Liu, Dongwook Kim, Yahui Li, Peng Wang, Yun Liao, Xiaolei Liu, Dan Yang, et al.fludarabine (HY-B0069), gemcitabine (HY-17026), hydroxyurea (HY-B0313), cladribine (HY-13599), triapine (HY-10082), nelarabine (HY-13701), doxycycline (HY-N0565), and D-luciferin potassium (HY-12591B) were purchased

(2) RRM1 inhibition sensitizes lung adenocarcinoma to decitabine treatmentCell Death & DiseaseFebruary 26, 2026Nan Jiang, Jianyong Liu, Ajay Vaghasia, Nicole Anders, Michelle Rudek, William G. Nelson, Srinivasan Yegnasubramanian, Jianya Zhouintervals. Chemicals Decitabine (DAC, 5-Aza-2‘-deoxycytidine, #HY-A0004, CAS No. 2353-33-5), triapine (3-AP, #HY-10082, CAS No. 143621-35-6), clofarabine (CLO, #HY-A0005, CAS No. 123318-82-1), and hydroxyurea (HU, #HY-B0313,

(3) Blockade of de novo dNTP biosynthesis pathway delays HIV-1 early life cycle kinetics and dynamicsmBioAugust 13, 2025Mohammad Anwar Siddique, Michael D. McRaven, Muhammad Shoaib Arif, Edward J. Allen, Charia McKee, Shravya Honne, Tahmina Sultana, Baek Kim, Ann M. Carias, João I. Mamede, et al.2.5 µM. Hydroxyurea/HU (H8627, Sigma-Aldrich), COH29 (HY-19931, MedchemExpress), and triapine/3-AP (HY-10082, MedChemExpress) were used at final concentration depending on the cell types based on respective inhibitor

(4) Inhibition of ribonucleotide reductase subunit M2 enhances the radiosensitivity of metastatic pancreatic neuroendocrine tumorCancer LettersAugust 1, 2024Zeta Chow, Jeremy Johnson, Aman Chauhan, Jong Cheol Jeong, Jennifer T. Castle, Tadahide Izumi, Heidi Weiss, Courtney M. Townsend, Jörg Schrader, Lowell Anthony, et al.previously [21]. Selective RRM2 inhibitor, 3-AP. RRM2 inhibitor, 3-AP (Triapine; PAN-811; OCX191; HY-10082), used for in vitro studies was purchased from MedChemExpress®. Drug was diluted in dimethyl sulfoxide

(5) A dose escalation and pharmacodynamic study of triapine and radiation in patients with locally advanced pancreas cancerInternational journal of radiation oncology, biology, physicsNovember 15, 2012Martin LK, Grecula J, Jia G, Wei L, Yang X, Otterson GA, Wu X, Harper E, Kefauver C, Zhou BS, et al.

(6) The anticancer thiosemicarbazones Dp44mT and triapine lack inhibitory effects as catalytic inhibitors or poisons of DNA topoisomerase IIαBiochemical pharmacologyJuly 1, 2012Yalowich JC, Wu X, Zhang R, Kanagasabai R, Hornbaker M, Hasinoff BB.

(7) A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeuticsProceedings of the National Academy of Sciences of the United States of AmericaOctober 3, 2006Whitnall M, Howard J, Ponka P, Richardson DR.

(8) The milled bar overdenture prosthesisThe Implant Society : [periodical]January 1, 1995Smith JJ.

Be the First to Write a Review!

Triapine from MedChemExpress

Description

MedChemExpress

Citations (8)

Reviews

Triapine from MedChemExpress

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map