Description
Rhodionin, isolated from the root of Rhodiola crenulata, is a specific non-competitive cytochrome P450 2D6 inhibitor with an IC50 of 0.761 µM and a Ki of 0.769 µM. Rhodionin exhibits potent, dose-dependent inhibitory effects on acetylcholinesterase (AChE) with IC50 ranged from 57.50 to 2.43 µg/mL. Rhodionin exhibits potent DPPH free radical scavenging activities, with an IC50 of 19.49 µM