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Protein Biochemistry
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DPN
DPN from MedChemExpress
Be the first to write a review!
Citations:
(9)
Supplier Page
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MedChemExpress for
DPN
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Description
DPN (Diarylpropionitrile) is a non-steroidal
estrogen receptor β (ERβ)
selective ligand, with an
EC
50
of 0.85 nM. DPN has neuroprotective effects in a number of neurological diseases
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
DPN
Company
MedChemExpress
Price
$73.00
Supplier Page
View Company Product Page
Catalog Number
HY-12452
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.66%
Type
Chemical
Molecular Weight
239.27
Molecule Name
DPN
Formula
C15H13NO2
Research Area
Neurological Disease
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (9)
(1)
Betulinic Acid Suppresses UBE2T Expression via MAPK/ERK Inhibition to Block FANCI and FANCD2 Monoubiquitination in Glioblastoma
J Cell Mol Med
January 4, 2026
Yifeng Bao, Maode Wang
(
MedChemExpress
, Cat. No.
HY‐P700520
) was used at 100 ng/mL for 6 h [21].
DPN
(
MedChemExpress
, Cat. No.
HY‐12452
) was used at 10 nM for 4 h [22]. Recombinant human IGF‐1 (
MedChemExpress
, Cat. No.
HY‐P70698
) was used
(2)
Reiterated male-to-female violence disrupts hippocampal estrogen receptor β expression, prompting anxiety-like behavior
iScience
September 20, 2024
Agrimi J, Bernardele L, Sbaiti N, Brondi M, D'Angelo D, Canato M, Marchionni I, Oeing CU, Barbara G, Vignoli B,
et al
.
proteins" ,,
BrdU
,
Invitrogen
,"
B23151
, CAS 59-14-3"
PHTPP
,
Santa Cruz Biotechnology
,CAS 805239-56-9
DPN
,
MedChemExpress
,"
HY-12452
, CAS 1428-67-7" ,, Critical commercial
assays
,Critical commercial
assays
,Critical commercial
assays
,,
TUNEL Assay
(3)
Astrocytic YAP prevents the demyelination through promoting expression of cholesterol synthesis genes in experimental autoimmune encephalomyelitis
Cell Death & Disease
October 5, 2021
Jingjing Zhang, Xingxing Xu, Huitao Liu, Lingting Jin, Xiya Shen, Changnan Xie, Weiwei Xiang, Danlu Yang, Wenjin Feng, Jiaojiao Wang,
et al.
intraperitoneally with 1 mg/kg, given every 2 d [41] after EAE induction. For
DPN
(ERβ-ligand) treatment,
DPN
(
HY-12452
,
MedChemExpress
) was first dissolved in 10% DMSO, and then dissolved in 90%
corn
oil, reducing the final
(4)
ERβ promotes Aβ degradation via the modulation of autophagy
Cell death & disease
July 22, 2019
Wei Y, Zhou J, Wu J, Huang J.
cultured in a humidified atmosphere of 5% CO2 at 37 °C incubator. Reagents used in this study were
DPN
(
HY-12452
; an ERβ-selective agonist) and CQ (
HY-17589
; a
lysosome
inhibitor
) from
MedChemExpress
(NJ, USA). All
(5)
Physiological dosages of estradiol and diarylpropionitrile decrease depressive behavior and increase tryptophan hydroxylase expression in the dorsal raphe nucleus of rats subjected to the forced swim test
Neuroreport
January 16, 2019
Yang F, Cheung A, Tao J, Zhao N, Wan W, Sheng J.
(6)
Effects of long-term dietary administration of estrogen receptor-beta agonist diarylpropionitrile on ovariectomized female ICR (CD-1) mice
GeroScience
August 1, 2018
Said SA, Isedowo R, Guerin C, Nar NN, Lillie L, Bukovac S, Simone JJ, Green MR, McCormick CM, Stuart JA.
(7)
Neuroprotective effects of diarylpropionitrile against β-amyloid peptide-induced neurotoxicity in rat cultured cortical neurons
Neuroscience letters
August 22, 2014
Suwanna N, Thangnipon W, Soi-Ampornkul R.
(8)
Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues
Journal of medicinal chemistry
November 22, 2001
Meyers MJ, Sun J, Carlson KE, Marriner GA, Katzenellenbogen BS, Katzenellenbogen JA.
(9)
[Posttraumatic soft tissue ossification of the forearm]
Hefte zur Unfallheilkunde
January 1, 1978
Schöttle H, Jungbluth KH, Schöntag H.
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DPN from MedChemExpress
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$73.00
Product Specs
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