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Protein Biochemistry
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Repotrectinib
Repotrectinib from MedChemExpress
Be the first to write a review!
Citations:
(5)
Supplier Page
Supplier Page from
MedChemExpress for
Repotrectinib
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Description
Repotrectinib (TPX-0005) is a potent
ROS1
(
IC
50
=0.07 nM) and
TRK
(
IC
50
=0.83/0.05/0.1 nM for TRKA/B/C) inhibitor. Repotrectinib potently inhibits WT
ALK
(
IC
50
=1.01 nM). Repotrectinib has anti-cancer activity
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Repotrectinib
Company
MedChemExpress
Price
$121.00
Supplier Page
View Company Product Page
Catalog Number
HY-103022
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.93%
Type
Chemical
Molecular Weight
355.37
Formula
C₁₈H₁₈FN₅O₂
Research Area
Cancer
Add to Compare List
MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (5)
(1)
Zidesamtinib Selective Targeting of Diverse ROS1 Drug-Resistant Mutations
Molecular Cancer Therapeutics
July 2, 2025
Anupong Tangpeerachaikul, Scot Mente, Joe Magrino, Franklin Gu, Joshua C. Horan, Henry E. Pelish
taletrectinib (
MedChemExpress
, #
HY-131003
), repotrectinib (Ark Pharm Inc., #AK689211;
MedChemExpress
, #
HY-103022
; SelleckChem, #S8583; DC Chemicals, #DC10463), and N-ethyl-N-nitrosourea (ENU;
Sigma
, #
D2650
). Zidesamtinib
(2)
A novel TRKB-activating internal tandem duplication characterizes a new mechanism of receptor tyrosine kinase activation
NPJ Precis Oncol
May 10, 2025
Lauren M. Brown, Gabor Tax, Pablo Acera Mateos, Antoine de Weck, Steve Foresto, Thomas Robertson, Fatimah Jalud, Pamela Ajuyah, Paulette Barahona, Jie Mao,
et al.
Receptor,
MedChemExpress
,
HY-101977
Entrectinib
,ALK; ROS; Trk Receptor,
MedChemExpress
,
HY-12678
Repotrectinib
,ALK; ROS; Trk Receptor,
MedChemExpress
,
HY-103022
Trametinib
,MEK,
MedChemExpress
,
HY-10999
Pimasertib
,MEK,
MedChemExpress
,
HY-12042
Paxalisib
,mTOR; PI3K,
MedChemExpress
,
HY-19962
Ruxolitinib
,JAK,
MedChemExpress
,
HY-50856
Dasatinib
,Bcr-Abl;
(3)
Ex vivo Drug Sensitivity Imaging-based Platform for Primary Acute Lymphoblastic Leukemia Cells
Bio Protoc
August 5, 2023
Lauren Rowland, Brandon Smart, Anthony Brown, Gino M. Dettorre, Yoshihiro Gocho, Jeremy Hunt, Wenjian Yang, Satoshi Yoshimura, Noemi Reyes, Guoqing Du,
et al.
nM",10 27,
Larotrectinib
,
MedChemExpress
,
HY-12866
,10 mM,-80 °C,DMSO,"0.1–10,000 nM",10 28,
Repotrectinib
,
MedChemExpress
,
HY-103022
,10 mM,-80 °C,DMSO,"0.1–10,000 nM",10 29,
Sorafenib
,
MedChemExpress
,
HY-10201
,10 mM,-80 °C,DMSO,"0.1–10,000
(4)
NVL-520 Is a Selective, TRK-Sparing, and Brain-Penetrant Inhibitor of ROS1 Fusions and Secondary Resistance Mutations
Cancer discovery
March 1, 2023
Drilon A, Horan JC, Tangpeerachaikul A, Besse B, Ou SI, Gadgeel SM, Camidge DR, van der Wekken AJ, Nguyen-Phuong L, Acker A,
et al
.
taletrectinib (
MedChemExpress
, #
HY-131003
), repotrectinib (Ark Pharm Inc., #AK689211;
MedChemExpress
, #
HY-103022
; SelleckChem, #S8583; DC Chemicals, #DC10463), and lorlatinib (Ark Pharm Inc., #AK175603; eNovation
(5)
Common Co-activation of AXL and CDCP1 in EGFR-mutation-positive Non-smallcell Lung Cancer Associated With Poor Prognosis
EBioMedicine
March 1, 2018
Karachaliou N, Chaib I, Cardona AF, Berenguer J, Bracht JWP, Yang J, Cai X, Wang Z, Hu C, Drozdowskyj A,
et al
.
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Repotrectinib from MedChemExpress
Supplier Page
View Company Product Page
$121.00
Product Specs
Company Info
Citations
Reviews
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