Troglitazone from MedChemExpress

Product Specs
ItemTroglitazone
CompanyMedChemExpress
Price $123.00Supplier Page View Company Product Page
Catalog NumberHY-50935
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.78%
FormulaC24H27NO5S
Research AreaMetabolic Disease; Cancer
TypeChemical
Molecular Weight441.54
Quantity10 mM * 1 mL
Molecule NameTroglitazone

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(1) BK channel deficiency promotes lipolysis via an AKT-independent activation of the cAMP/PKA/HSL pathwayJournal of Lipid ResearchJune 30, 2026Jin Zhang, Xin Shi, Mengxuan Zhang, Yuying Han, Guang Yang, Ruiyang Li, Feng Zhao, Ping Liu, Xinxin Wen, Wenxuan Wei, et al.(Cat# I5879, Sigma-Aldrich), 1 μM dexamethasone (Cat# D4902, Sigma-Aldrich), 5 μM troglitazone (Cat# HY-50935, MCE), and 10% FBS in DMEM/F12 (1:1 vol/vol). After 48 h, differentiation medium I was replaced with

(2) Optimized Ex Vivo Human Liver Slice Culture Maintains Extended Viability and Function for Hepatotoxicity TestingAdvanced ScienceJune 29, 2026Huiche Feng, Cinzia Esposito, Andrej Benjak, Matthias S. Matter, Miriam Cieri, Camilla De Carlo, Philipp Sedlaczek, Fabian Haak, Mattia Marinucci, Gabriel Fridolin Hess, et al.liver tissue culture medium and were then treated with troglitazone (10–50 µm; MedChemExpress, Cat# HY‐50935) or acetaminophen (APAP, 10–50 mm; MedChemExpress, Cat# HY‐66005) at the indicated concentrations. Stock

(3) Promoting APC function of B cells via reprogramming the fatty acid metabolism enhances anticancer immunity in metastatic ovarian cancerCancer Immunol ImmunotherApril 15, 2026Haoke Zhang, Chunyan Yu, Wei Du, Huiyang Li, Zihe Liu, Xueying Li, Yuhan Yue, Bo Wang, Hongmei Wang, Yuqing Ouyang, et al.MedChemExpress; Cat# HY-16578; 25 μM), and PPARγ agonist (Troglitazone, Trog, MedChemExpress; Cat# HY-50935; 10 μM) for 2h, respectively. Then the cells were washed with PBS twice, inoculated on a 12-well plate,

(4) Distinct Roles of Matrigel Enabled the Production of Expandable Hepatoblast and Polarized Hepatocyte Organoids from Human Embryonic Stem Cells under 3-Dimensional Suspension ConditionsBiomaterials ResearchNovember 7, 2025Haibin Wu, Jue Wang, Shoupei Liu, Yiyu Wang, Jinghe Xie, Xueyan Zhang, Shuai Zhang, Weili Gu, Yongjian Zhou, Yuyou DuanMedChemExpress, HY-N0378), troglitazone (0, 0.1, 1, 5, 10, 50, 100, 500, and 1,000 μM; MedChemExpress, HY-50935), chlorpromazine (0, 0.01, 0.05, 0.1, 1, 10, 50, 100, and 1,000 μM; Selleck, S5749), diclofenac (0,

(5) PPARG-centric transcriptional re-wiring during differentiation of human trophoblast stem cells into extravillous trophoblastsNucleic Acids ResJuly 24, 2025Qingqing Guo, Joonhyuk Choi, Muyoung Lee, Jonghwan Kim(Selleck Chemicals, S2098; 1 μM), CD3254 (Fisher Scientific, 33-025-0; 1 μM), Troglitazone (MedChemExpress, HY-50935; 1 μM), DMOG (Selleck Chemicals, S7483; 500 μM), and SCH772984 (MedChemExpress, HY-50846; 0.5 μM). shRNA

(6) High-intensity interval training induces lactylation of fatty acid synthase to inhibit lipid synthesisBMC BiologySeptember 19, 2023Xuefei Chen, Wenhua Huang, Jingbo Zhang, Yanjun Li, Zheng Xing, Lanlan Guo, Hongfeng Jiang, Jing ZhangDarmstadt, Germany), 1 µM dexamethasone (D1756, Sigma–Aldrich, Darmstadt, Germany), 0.5 mM troglitazone (HY-50935, MCE, NJ, USA), and 0.5 mM IBMX (I7018, Sigma–Aldrich, Darmstadt, Germany) for 2 days. Then, the medium

(7) Application of 3D Hepatic Plate-Like Liver Model for Statin-Induced Hepatotoxicity EvaluationFrontiers in bioengineering and biotechnologyJanuary 1, 2022Xu J, Pan D, Liao W, Jia Z, Pan M, Weng J, Han X, Li S, Li Y, Liang K, et al.used in this experiment included isoniazid (INH, HY-B0329; MedChemExpress (MCE)), troglitazone (TZD, HY-50935; MCE), and amiodarone hydrochloride (AMD, HY-14188; MCE). Metformin hydrochloride (HY-17471A; MCE) is

(8) In vitro and in vivo cytotoxicity of troglitazone in pancreatic cancerJournal of experimental & clinical cancer research : CRJuly 3, 2017Fujita M, Hasegawa A, Yamamori M, Okamura N.

(9) The PPARs: from orphan receptors to drug discoveryJournal of medicinal chemistryFebruary 24, 2000Willson TM, Brown PJ, Sternbach DD, Henke BR.

(10) Conformational populations for antihistamines and antihypertensives in solutionJournal of pharmaceutical sciencesApril 1, 1976Ham NS.

(11) PPARγ activation by troglitazone enhances human lung cancer cells to TRAIL-induced apoptosis via autophagy fluxOncotargetJanuary 1, 0001"Nazim UM, Moon JH, Lee YJ, Seol JW, Park SY."

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Troglitazone from MedChemExpress

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Troglitazone from MedChemExpress

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