PD 407824 from MedChemExpress | Biocompare.com

Be the first to write a review!

Citations:

Supplier Page from
MedChemExpress for
PD 407824

Description

PD 407824 is a checkpoint kinase Chk1 and WEE1 inhibitor with IC₅₀s of 47 and 97 nM, respectively. PD 407824 is a chemical BMP sensitizer and increases the sensitivity of cells to sub-threshold amounts of BMP4

Product Specs
ItemPD 407824
CompanyMedChemExpress
Price $138.00Supplier Page View Company Product Page
Catalog NumberHY-18961
Research AreaInflammation/Immunology; Cancer
FormulaC₂₀H₁₂N₂O₃
Molecular Weight328.32
TypeChemical
Purity99.00%
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Quantity10 mM * 1 mL

Add to Compare List

MedChemExpress

MedChemExpress

1 Deer Park Drive, Suite F

MONMOUTH JUNCTION, NJ 08852

United States

Phone: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910

Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com

Company Profile

Website: medchemexpress.com

(1) Discovery of a Small-Molecule BMP Sensitizer for Human Embryonic Stem Cell DifferentiationCell reportsMay 31, 2016Feng L, Cook B, Tsai SY, Zhou T, LaFlamme B, Evans T, Chen S.

(2) Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinasesEuropean journal of medicinal chemistryJune 1, 2008Smaill JB, Baker EN, Booth RJ, Bridges AJ, Dickson JM, Dobrusin EM, Ivanovic I, Kraker AJ, Lee HH, Lunney EA, et al.

(3) 4-Phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione inhibitors of the checkpoint kinase Wee1. Structure-activity relationships for chromophore modification and phenyl ring substitutionJournal of medicinal chemistryAugust 10, 2006Palmer BD, Thompson AM, Booth RJ, Dobrusin EM, Kraker AJ, Lee HH, Lunney EA, Mitchell LH, Ortwine DF, Smaill JB, et al.

(4) [Approach to prognosis of hepatic schistosomiasis caused by Schistosoma mansoni]La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de ParisJune 8, 1974Le Bras M, Bertrand E.

Be the First to Write a Review!